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1.发明申请CONTAINER TRACKING AND LOCATING SYSTEMS, METHODS, AND COMPUTER PROGRAM PRODUCTS 审中-公开集装箱跟踪和定位系统，方法和计算机程序产品公开(公告)号：US20110017693A1
公开(公告)日：2011-01-27
申请号：US12840983
申请日：2010-07-21
CPC分类号： B66C13/44 , B66C13/16 , B66C19/002 , G06Q10/08 , H04Q2213/13095
摘要： Provided are systems, methods, and computer-program products for tracking and locating shipping containers in rail car unloading operations in a railway switchyard using a rail mounted gantry crane. The systems, methods, and computer program products configured to establish the position of shipping containers loaded on rail cars within a rail yard. The position of the shipping containers can be conveyed in terms of relative or absolute coordinates. The systems, methods, and computer program products can use a variety of inputs, rules, and calculations to establish the final resting places of containers mounted on rail cars. The position information may be used to provide various functionality, including creating a log or record of the location of containers or to guide rail mounted gantry (RMG) cranes to unload and work the train(s) of interest.
摘要翻译： 提供了一种系统，方法和计算机程序产品，用于跟踪和定位使用轨道式龙门起重机的铁路车库卸货作业中的集装箱。 系统，方法和计算机程序产品被配置为建立装载在铁路车厢内的运输集装箱的位置。 运输集装箱的位置可以根据相对坐标或绝对坐标进行传送。 系统，方法和计算机程序产品可以使用各种输入，规则和计算来建立安装在轨道车上的集装箱的最终休息位置。 位置信息可以用于提供各种功能，包括创建容器的位置的日志或记录，或者引导轨道安装的龙门架（RMG）起重机来卸载和操作感兴趣的列车。
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公开(公告)号：US07879885B2
公开(公告)日：2011-02-01
申请号：US10593911
申请日：2005-03-23
申请人： Steven A. Boyd , Kevin R. Condroski , Allen Thomas , Stephen S. Gonzales , Indrani W. Gunawardana , Yvan Le Huerou , Todd T. Romoff , Francis X. Sullivan
发明人： Steven A. Boyd , Kevin R. Condroski , Allen Thomas , Stephen S. Gonzales , Indrani W. Gunawardana , Yvan Le Huerou , Todd T. Romoff , Francis X. Sullivan
IPC分类号： A61K31/44
CPC分类号： C07D213/73 , C07D405/12 , C07D411/12
摘要： The present invention provides thioalkeneamides of formula (I) which are useful as transketolase inhibitors: wherein R1, R2, R3, R4, R5, R6, Ra-Rd, n and ring A are as defined herein. The present invention also provides pharmaceutical compositions comprising the compounds of formula (I). The invention provides methods for inhibiting transketolase activity, reducing cellular ribose-5-phosphate levels, inhibiting nucleic acid synthesis, inhibiting cell proliferation and tumor cell growth in vitro and in vivo, stimulating apoptosis in tumor cells and treating cancer by administering a compound of formula (I) or a pharmaceutical composition thereof.
摘要翻译： 本发明提供了可用作转酮酶抑制剂的式（I）的硫代链烯酰胺：其中R1，R2，R3，R4，R5，R6，Ra-Rd，n和环A如本文所定义。 本发明还提供包含式（I）化合物的药物组合物。 本发明提供了抑制转酮醇酶活性，减少细胞核糖-5-磷酸水平，抑制核酸合成，抑制体外和体内细胞增殖和肿瘤细胞生长，刺激肿瘤细胞凋亡和通过给予式 （I）化合物或其药物组合物。
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公开(公告)号：US20050003751A1
公开(公告)日：2005-01-06
申请号：US10858884
申请日：2004-06-02
申请人： Allen Thomas
发明人： Allen Thomas
IPC分类号： B60H1/26 , B60J20060101
CPC分类号： B60H1/262 , B60H1/00364
摘要： A collapsible air vent closure is disclosed comprising a frame having a frame aperture. A closure is mounted to the frame for pivoting between a closed position and an open position. A movable vent wall having a vent orifice is interposed between the frame and the closure. The vent orifice provides an air flow path to the frame aperture when the closure is in the open position. The closure inhibits the air flow path to the frame aperture when the closure is in the closed position.
摘要翻译： 公开了一种可折叠的通气口，其包括具有框架孔的框架。 闭合件安装到框架上用于在关闭位置和打开位置之间枢转。 具有通气孔的可移动排气壁插入在框架和封闭件之间。 当封闭件处于打开位置时，排气孔提供到框架孔的空气流动路径。 当封闭件处于关闭位置时，封闭件阻止到框架孔的空气流动路径。
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公开(公告)号：US20070019499A1
公开(公告)日：2007-01-25
申请号：US11186168
申请日：2005-07-21
申请人： Brett Shumaker , Allen Thomas , Craig Beal , Matthew Keiser , Robert Decker , Steven Shooter
发明人： Brett Shumaker , Allen Thomas , Craig Beal , Matthew Keiser , Robert Decker , Steven Shooter
IPC分类号： B28C5/42
CPC分类号： B28C5/4248 , B28C5/4255 , B28C5/4258
摘要： A concrete mixer truck includes a truck chassis having a cab mounted at the front of the chassis. A mixing drum adapted to receive, mix and dispense concrete is mounted at a rear end of the chassis. The drum has a discharge end which faces the cab. A collector is located above the cab roof and is spaced apart from the mixing drum. A conveyor device mounted on a support frame is located generally between the cab and the drum and is utilized to transport concrete from the discharge end of said mixing drum up an inclined slope to the collector. A placement chute system directs a gravity flow of concrete from said collector to a desired location. The mixer truck utilizes the chassis, drum and other components of a standard rear discharge mixer truck to create a new type of front discharge mixer which has many of the advantages of existing front discharge mixer trucks at a reduced cost.
摘要翻译： 混凝土搅拌车包括具有安装在底盘前部的驾驶室的卡车底盘。 适用于接收，混合和分配混凝土的混合鼓安装在底盘的后端。 滚筒具有面向驾驶室的排出端。 收集器位于驾驶室车顶顶部并与混合鼓间隔开。 安装在支撑框架上的传送装置通常位于驾驶室和滚筒之间，并且用于将混凝土从所述混合鼓的排出端向倾斜的斜坡运送到收集器。 放置滑槽系统将混凝土的重力流从所述收集器引导到期望的位置。 搅拌车采用标准后排式混合动力车的底盘，鼓轮和其他部件，创造出一种新型的前排气混合器，具有现有的前排式混合动力卡车的许多优点，降低了成本。
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公开(公告)号：US20070238726A1
公开(公告)日：2007-10-11
申请号：US11714342
申请日：2007-03-06
申请人： James Blake , Steven Boyd , Jason De Meese , Kin Fong , John Gaudino , Tomas Kaplan , Allison Marlow , Jeongbeob Seo , Allen Thomas , Hongqi Tian , Frederick Cohen , Wendy Young
发明人： James Blake , Steven Boyd , Jason De Meese , Kin Fong , John Gaudino , Tomas Kaplan , Allison Marlow , Jeongbeob Seo , Allen Thomas , Hongqi Tian , Frederick Cohen , Wendy Young
IPC分类号： A61K31/541 , A61K31/5377 , A61K31/496 , A61K31/4745 , C07D471/02
CPC分类号： C07D471/04
摘要： Compounds of Formulas Ia and Ib, and stereoisomers, geometric isomers, tautomers, solvates, metabolites and pharmaceutically acceptable salts thereof, are useful for inhibiting receptor tyrosine kinases and for treating disorders mediated thereby. Methods of using compounds of Formula Ia and Ib, and stereoisomers, geometric isomers, tautomers, solvates and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed.
摘要翻译： 式Ia和Ib的化合物及其立体异构体，几何异构体，互变异构体，溶剂合物，代谢物和药学上可接受的盐可用于抑制受体酪氨酸激酶和用于治疗由此介导的病症。 使用式Ia和Ib化合物及其立体异构体，几何异构体，互变异构体，溶剂化物及其药学上可接受的盐的方法用于体外，原位和体内诊断，预防或治疗哺乳动物细胞中的这种病症或相关病理学 条件被公开。
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公开(公告)号：US20090209554A1
公开(公告)日：2009-08-20
申请号：US10593910
申请日：2005-03-23
申请人： Steven A. Boyd , Kevin R. Condroski , Jason De Meese , Stephen S. Gonzales , Indrani W. Gunawardana , Tomas Kaplan , Yvan Le Huerou , Joseph Lyssikatos , Todd T. Romoff , Francis X. Sullivan , Allen Thomas
发明人： Steven A. Boyd , Kevin R. Condroski , Jason De Meese , Stephen S. Gonzales , Indrani W. Gunawardana , Tomas Kaplan , Yvan Le Huerou , Joseph Lyssikatos , Todd T. Romoff , Francis X. Sullivan , Allen Thomas
IPC分类号： A61K31/497 , C12N9/99 , C12N5/06 , A61K31/4439 , A61P35/00 , C07D417/06
CPC分类号： C07D417/06 , C07D417/14
摘要： The present invention provides N-3′-pyridyl-methyl or N-2′-pyrazinylmethyl thiazolium derivatives of formula (I) which are useful as transketolase inhibitors wherein R1, R2, R3, Y, R5-R9, Ra-Rd, n and X− are as defined herein. The present invention also provides pharmaceutical compositions comprising the compounds of formula (I). The invention provides methods for inhibiting transketolase activity, reducing cellular ribose-5-phosphate levels, inhibiting nucleic acid synthesis, inhibiting cell proliferation and tumor cell growth in vitro and in vivo, stimulating apoptosis in tumor cells and treating cancer by administering a compound of formula (I) or a pharmaceutical composition thereof.
摘要翻译： 本发明提供了可用作转酮酶抑制剂的式（I）的N-3'-吡啶基 - 甲基或N-2'-吡嗪基甲基噻唑鎓衍生物，其中R1，R2，R3，Y，R5-R9，Ra-Rd，n 和X-如本文所定义。 本发明还提供包含式（I）化合物的药物组合物。 本发明提供了抑制转酮醇酶活性，减少细胞核糖-5-磷酸水平，抑制核酸合成，抑制体外和体内细胞增殖和肿瘤细胞生长，刺激肿瘤细胞凋亡和通过给予式 （I）化合物或其药物组合物。
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公开(公告)号：US20080066928A1
公开(公告)日：2008-03-20
申请号：US11943641
申请日：2007-11-21
申请人： Allen Thomas , Jim Wiens , Michael Hayes
发明人： Allen Thomas , Jim Wiens , Michael Hayes
摘要： A method and apparatus for remotely performing a pipe handling operation is provided. In one aspect, the method and apparatus includes a false rotary table capable of supporting one or more tubulars during the pipe handling operation which is moveable between a position for landing one or more tubulars to a position for running one or more tubulars into a wellbore. In another aspect, the present invention provides a method and apparatus for remotely connecting elevator links alternatingly between interchangeable elevators which are capable of axially engaging one or more tubulars above the wellbore.
摘要翻译： 提供一种用于远程执行管道处理操作的方法和装置。 在一个方面，该方法和装置包括一个假旋转台，其能够在管道处理操作期间支撑一个或多个管状体，其可在用于将一个或多个管子着陆到用于将一个或多个管子运送到井眼中的位置之间移动。 在另一方面，本发明提供了一种用于在可互换电梯之间交替地远程连接电梯链路的方法和装置，其能够轴向地接合在井眼上方的一个或多个管。
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公开(公告)号：US20070293501A1
公开(公告)日：2007-12-20
申请号：US10593911
申请日：2005-03-23
申请人： Steven Boyd , Kevin Condroski , Allen Thomas , Stephen Gonzales , Indrani Gunawardana , Yvan Huerou , Todd Romoff , Francis Sullivan
发明人： Steven Boyd , Kevin Condroski , Allen Thomas , Stephen Gonzales , Indrani Gunawardana , Yvan Huerou , Todd Romoff , Francis Sullivan
IPC分类号： A61K31/44 , A61K31/444 , A61K31/4965 , A61K31/497 , A61P35/00 , C07D213/70 , C07D401/12 , C07D403/12
CPC分类号： C07D213/73 , C07D405/12 , C07D411/12
摘要： The present invention provides thioalkeneamides of formula (I) which are useful as transketolase inhibitors: wherein R1, R2, R3, R4, R5, R6, Ra-Rd, n and ring A are as defined herein. The present invention also provides pharmaceutical compositions comprising the compounds of formula (I). The invention provides methods for inhibiting transketolase activity, reducing cellular ribose-5-phosphate levels, inhibiting nucleic acid synthesis, inhibiting cell proliferation and tumor cell growth in vitro and in vivo, stimulating apoptosis in tumor cells and treating cancer by administering a compound of formula (I) or a pharmaceutical composition thereof.
摘要翻译： 本发明提供了可用作转酮酶抑制剂的式（I）的硫代链烯酰胺：其中R 1，R 2，R 3，R 3， R 4，R 5，R 6，R 9，R 11， 环A如本文所定义。 本发明还提供包含式（I）化合物的药物组合物。 本发明提供了抑制转酮醇酶活性，减少细胞核糖-5-磷酸水平，抑制核酸合成，抑制体外和体内细胞增殖和肿瘤细胞生长，刺激肿瘤细胞凋亡和通过给予式 （I）化合物或其药物组合物。
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公开(公告)号：US20070197537A1
公开(公告)日：2007-08-23
申请号：US11699830
申请日：2007-01-30
申请人： James Blake , Steven Boyd , Jason De Meese , John Gaudino , Allison Marlow , Jeongbeob Seo , Allen Thomas , Hongqi Tian
发明人： James Blake , Steven Boyd , Jason De Meese , John Gaudino , Allison Marlow , Jeongbeob Seo , Allen Thomas , Hongqi Tian
IPC分类号： A61K31/503 , A61K31/519 , A61K31/4743 , C07D498/02
CPC分类号： C07D495/04 , C07D519/00
摘要： Compounds of Formula I and pharmaceutically acceptable salts thereof, are useful for inhibiting receptor tyrosine kinases and for treating disorders mediated thereby. Methods of using compounds of Formula I and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed.
摘要翻译： 式I化合物及其药学上可接受的盐可用于抑制受体酪氨酸激酶和用于治疗由此介导的病症。 公开了使用式I化合物及其药学上可接受的盐在体外，原位和体内诊断，预防或治疗哺乳动物细胞或相关病理状况中的这种病症的方法。
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公开(公告)号：US20060027375A1
公开(公告)日：2006-02-09
申请号：US10945544
申请日：2004-09-20
申请人： Allen Thomas , Jim Wiens , Michael Hayes
发明人： Allen Thomas , Jim Wiens , Michael Hayes
摘要： A method and apparatus for remotely performing a pipe handling operation is provided. In one aspect, the method and apparatus includes a false rotary table capable of supporting one or more tubulars during the pipe handling operation which is moveable between a position for landing one or more tubulars to a position for running one or more tubulars into a wellbore. In another aspect, the present invention provides a method and apparatus for remotely connecting elevator links alternatingly between interchangeable elevators which are capable of axially engaging one or more tubulars above the wellbore.
摘要翻译： 提供一种用于远程执行管道处理操作的方法和装置。 在一个方面，该方法和装置包括一个假旋转台，其能够在管道处理操作期间支撑一个或多个管状体，其可在用于将一个或多个管子着陆到用于将一个或多个管子运送到井眼中的位置之间移动。 在另一方面，本发明提供了一种用于在可互换电梯之间交替地远程连接电梯链路的方法和装置，其能够轴向地接合在井眼上方的一个或多个管。
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