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公开(公告)号:US07776521B1
公开(公告)日:2010-08-17
申请号:US11748359
申请日:2007-05-14
申请人: Paul A. Rota , Larry J. Anderson , William J. Bellini , Michael D. Bowen , Cara Carthel Burns , Raymond Campagnoli , Qi Chen , James A. Comer , Byron T. Cook , Shannon L. Emery , Dean D. Erdman , Cynthia S. Goldsmith , Jeanette Guarner , Charles D. Humphrey , Joseph P. Icenogle , Thomas G. Ksiazek , Richard F. Meyer , Stephan S. Monroe , William Allan Nix , M. Steven Oberste , Christopher D. Paddock , Teresa C. T. Peret , Pierre E. Rollin , Mark A. Pallansch , Anthony Sanchez , Wun-Ju Shieh , Suxiang Tong , Sherif R. Zaki
发明人: Paul A. Rota , Larry J. Anderson , William J. Bellini , Michael D. Bowen , Cara Carthel Burns , Raymond Campagnoli , Qi Chen , James A. Comer , Byron T. Cook , Shannon L. Emery , Dean D. Erdman , Cynthia S. Goldsmith , Jeanette Guarner , Charles D. Humphrey , Joseph P. Icenogle , Thomas G. Ksiazek , Richard F. Meyer , Stephan S. Monroe , William Allan Nix , M. Steven Oberste , Christopher D. Paddock , Teresa C. T. Peret , Pierre E. Rollin , Mark A. Pallansch , Anthony Sanchez , Wun-Ju Shieh , Suxiang Tong , Sherif R. Zaki
CPC分类号: C07K14/005 , A61K39/12 , A61K39/215 , C12N7/00 , C12N2770/20021 , C12N2770/20022 , C12N2770/20034
摘要: Disclosed herein is a newly isolated human coronavirus (SARS-CoV), the causative agent of severe acute respiratory syndrome (SARS). Also provided are the nucleic acid sequence of the SARS-CoV genome and the amino acid sequences of the SARS-CoV open reading frames, as well as methods of using these molecules to detect a SARS-CoV and detect infections therewith. Immune stimulatory compositions are also provided, along with methods of their use.
摘要翻译: 本文公开了新分离的人冠状病毒(SARS-CoV),严重急性呼吸综合征(SARS)的致病因子。 还提供了SARS-CoV基因组的核酸序列和SARS-CoV开放阅读框的氨基酸序列,以及使用这些分子检测SARS-CoV并检测其感染的方法。 还提供免疫刺激组合物及其使用方法。