公开(公告)号：US20120135032A1

公开(公告)日：2012-05-31

申请号：US13389411

申请日：2010-10-06

申请人： Paul Chaplin ,  Richard Nichols

发明人： Paul Chaplin ,  Richard Nichols

IPC分类号： A61K39/21 ,  A61P31/18

CPC分类号： A61K39/12 ,  A61K39/21 ,  A61K2039/5256 ,  A61K2039/545 ,  A61K2039/57 ,  C12N15/86 ,  C12N2710/24143 ,  C12N2710/24171 ,  C12N2740/16134 ,  C12N2740/16234 ,  C12N2740/16334

摘要： The present invention relates to a recombinant Modified Vaccinia virus Ankara (MVA) comprising in the viral genome one or more expression cassettes for the expression of HIV proteins selected from Gag, Pol, Tat, Vif, Vpu, Vpr, Rev and Nef or a part or a derivative thereof or selected from Gag, Pol, Vpu, Vpr, Rev and Nef or a part or a derivative thereof for use as medicament or vaccine and its use for the treatment and/or prevention of HIV infections and AIDS.

摘要翻译： 本发明涉及在病毒基因组中包含用于表达选自Gag，Pol，Tat，Vif，Vpu，Vpr，Rev和Nef的HIV蛋白质的一个或多个表达盒的重组修饰的痘苗病毒安卡拉（MVA） 或其衍生物或选自Gag，Pol，Vpu，Vpr，Rev和Nef或其部分或衍生物，用作药物或疫苗及其用于治疗和/或预防HIV感染和AIDS的用途。

公开(公告)号：US20070151260A1

公开(公告)日：2007-07-05

申请号：US11325304

申请日：2006-01-05

申请人： Richard Nichols ,  Sarah Hutcherson ,  Keith Belsom ,  Thomas Amond ,  Natesh Chandrashekar ,  Alberto Negroni

发明人： Richard Nichols ,  Sarah Hutcherson ,  Keith Belsom ,  Thomas Amond ,  Natesh Chandrashekar ,  Alberto Negroni

IPC分类号： F23R3/42

CPC分类号： F23R3/48

摘要： A crossfire tube for attachment between casing bosses of combustors includes a bellows assembly having a bellows with opposite cylindrical ends welded to annular flanges. The annular flanges include a bolt circle for securing the flanges to the combustor bosses. The flanges bear against a gasket for sealing against inserts welded to the casing bosses for retrofit in the sealing assembly to combustors or to seats where the inserts and bosses are formed integrally during original equipment manufacture. A telescoping cylindrical sleeve surrounds the bellows to protect from falling foreign object damage.

摘要翻译： 用于在燃烧器的壳体凸起之间附接的交叉火管包括具有波纹管的波纹管组件，其具有焊接到环形凸缘的相对的圆柱形端部。 环形凸缘包括用于将凸缘固定到燃烧器凸台的螺栓圆圈。 凸缘抵靠垫圈，用于密封焊接到套管凸台上的插入件，用于将密封组件改装为燃烧器或座椅，其中插入件和凸台在原始设备制造期间一体形成。 伸缩的圆柱形套筒围绕波纹管，以防止异物损坏。

公开(公告)号：US20140357319A1

公开(公告)日：2014-12-04

申请号：US14126516

申请日：2012-12-21

申请人： Alexander Maltsev ,  Ali Sadri ,  Richard Nichols ,  Vadim Sergeyev ,  Andrey Pudeyev ,  Alexei Davydov

发明人： Alexander Maltsev ,  Ali Sadri ,  Richard Nichols ,  Vadim Sergeyev ,  Andrey Pudeyev ,  Alexei Davydov

IPC分类号： H04B7/06 ,  H04B7/01

CPC分类号： H04B7/0667 ,  G01S3/38 ,  H01Q3/26 ,  H04B7/01

摘要： Generally, this disclosure provides systems and methods for modular antenna array beamforming with controllable antenna module delay for improved beam steering accuracy. A system may include a plurality of antenna modules, each of the antenna modules comprising an array of antenna elements coupled to an RF beamforming circuit, the RF beamforming circuit to adjust phase shifts associated with the antenna elements to generate an antenna beam associated with the antenna module; a delay circuit coupled to each of the antenna modules; and a central beamforming module coupled to each of the delay circuits, the central beamforming module to control the antenna beam associated with each of the antenna modules and further to adjust signal delays associated with the delay circuits, wherein the arrays of antenna elements of the antenna modules combine to operate as a composite antenna beamforming array.

摘要翻译： 通常，本公开提供了用于模块化天线阵列波束成形的系统和方法，其具有可控天线模块延迟以改善波束转向精度。 系统可以包括多个天线模块，每个天线模块包括耦合到RF波束成形电路的天线元件的阵列，RF波束形成电路来调整与天线元件相关联的相移以产生与天线相关联的天线波束 模块 耦合到每个天线模块的延迟电路; 以及耦合到每个延迟电路的中央波束成形模块，所述中央波束成形模块用于控制与每个天线模块相关联的天线波束，并且还调整与延迟电路相关联的信号延迟，其中天线的天线元件阵列 模块组合起来用作复合天线波束成形阵列。

公开(公告)号：US20070019686A1

公开(公告)日：2007-01-25

申请号：US11530618

申请日：2006-09-11

申请人： Jonathan Belk ,  Richard Nichols

发明人： Jonathan Belk ,  Richard Nichols

IPC分类号： H04J3/06

CPC分类号： H04J3/0632

摘要： A method for controlling a local clock in a node coupled to a packet network is disclosed. The method involves generating a first control signal based on RTS values received during a first period of time and generating at least one additional control signal based on RTS values received during at least one additional period of time. The method further involves selecting one of the first and at least one additional control signals to control the frequency of a local clock.

摘要翻译： 公开了一种用于控制耦合到分组网络的节点中的本地时钟的方法。 该方法包括基于在第一时间段期间接收的RTS值产生第一控制信号，并且基于在至少一个附加时间段期间接收的RTS值产生至少一个附加控制信号。 该方法还包括选择第一和至少一个附加控制信号之一来控制本地时钟的频率。

公开(公告)号：US20070039757A1

公开(公告)日：2007-02-22

申请号：US11423495

申请日：2006-06-12

申请人： Richard Nichols ,  Bruce Taylor ,  Roger Pierce

发明人： Richard Nichols ,  Bruce Taylor ,  Roger Pierce

IPC分类号： E21B17/00 ,  E21B7/00

CPC分类号： E21B17/00 ,  E21B7/28 ,  E21B17/02 ,  E21B17/16

摘要： The present invention provides drilling assembles and methods that are especially useful for a bottom hole drilling assembly for drilling/reaming/or other operations related to drilling a borehole through an earth formation. In one embodiment, the drilling assembly utilizes standard drill collars which are modified to accept force transfer sections. In another embodiment, the drilling assembly comprises a tension inducing sub which creates a force that may be used to place the bottom hole assembly or portions thereof in tension. In another embodiment, a reaming assembly is held in tension to provide a stiffer reaming assembly.

摘要翻译： 本发明提供了一种钻孔组件和方法，其特别适用于钻孔/铰孔的钻孔组件，或与通过地层钻探钻孔相关的其他操作。 在一个实施例中，钻井组件使用经修改以接受力传递部分的标准钻铤。 在另一个实施例中，钻孔组件包括张力引导子，其产生可用于将底部孔组件或其部分张紧的力。 在另一个实施例中，延伸组件保持张力以提供更硬的铰孔组件。