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公开(公告)号：US08239039B2
公开(公告)日：2012-08-07
申请号：US11215786
申请日：2005-08-30
IPC分类号： A61N1/05
CPC分类号： A61N1/057 , A61N2001/0578 , A61N2001/0585
摘要： This document discusses, among other things, a lead body extending longitudinally along a lead axis, a driver axially displaceable relative to the lead body, and a driven member coupled to the lead body and displaceable away from the lead axis. The driven member at least partially defines an expandable passage having at least one internal dimension. The driver is displaceable into the expandable passage and has at least one outer dimension that is larger than the at least one internal dimension of the expandable passage. An example method includes disposing a first member having a first cross-section in a lead assembly having a lead axis, an expandable passage, and a displaceable member proximate the expandable passage. The method further includes urging the first member into the expandable passage in the lead assembly, and urging the displaceable member away from the lead axis to expand the expandable passage.
摘要翻译： 本文件尤其讨论了沿着引线轴线纵向延伸的引线本体，相对于引线主体轴向移位的驱动器以及耦合到引线主体并且可远离引导轴线移位的从动元件。 从动构件至少部分地限定具有至少一个内部尺寸的可扩张通道。 驾驶员可移动到可扩张通道中并且具有比可扩张通道的至少一个内部尺寸大的至少一个外部尺寸。 示例性方法包括将具有第一横截面的第一构件布置在具有引导轴线的引导组件中，可扩展通道和靠近可扩展通道的可移位构件。 所述方法还包括将所述第一构件推入所述引导组件中的所述可膨胀通道中，并且将所述可移位构件推离所述引导轴线以使所述可扩张通道膨胀。
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公开(公告)号：US20110137383A1
公开(公告)日：2011-06-09
申请号：US13027849
申请日：2011-02-15
CPC分类号： A61N1/056 , A61N1/08 , A61N2001/083
摘要： An implantable lead assembly includes a lead body extending from a proximal end to a distal end having an intermediate portion therebetween, where the lead body includes an insulating layer. A conductor is disposed within the insulating layer and the insulating layer surrounds the conductor. An electrode is coupled to the lead body, and the electrode is in electrical communication with the conductor. At least one conductive sleeve is disposed within the insulating layer. The at least one conductive sleeve surrounds the conductor and is electrically isolated from the electrode. The at least one conductive sleeve has a first impedance value in a first condition.
摘要翻译： 可植入引线组件包括从近端延伸到远端的引线主体，其中之间具有中间部分，其中引线主体包括绝缘层。 导体设置在绝缘层内，绝缘层包围导体。 电极耦合到引线体，并且电极与导体电连通。 至少一个导电套管设置在绝缘层内。 所述至少一个导电套管围绕所述导体并且与所述电极电隔离。 所述至少一个导电套筒在第一状态下具有第一阻抗值。
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公开(公告)号：US07904174B2
公开(公告)日：2011-03-08
申请号：US10698843
申请日：2003-10-31
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61N1/08 , A61N2001/083
摘要： An implantable lead assembly includes a lead body extending from a proximal end to a distal end having an intermediate portion therebetween, where the lead body includes an insulating layer. A conductor is disposed within the insulating layer and the insulating layer surrounds the conductor. An electrode is coupled to the lead body, and the electrode is in electrical communication with the conductor. At least one conductive sleeve is disposed within the insulating layer. The at least one conductive sleeve surrounds the conductor and is electrically isolated from the electrode. The at least one conductive sleeve has a first impedance value in a first condition.
摘要翻译： 可植入引线组件包括引线本体，该引线体从近端延伸至具有中间部分的远端，其中引线主体包括绝缘层。 导体设置在绝缘层内，绝缘层包围导体。 电极耦合到引线体，并且电极与导体电连通。 至少一个导电套管设置在绝缘层内。 所述至少一个导电套管围绕所述导体并且与所述电极电隔离。 所述至少一个导电套筒在第一状态下具有第一阻抗值。
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公开(公告)号：US08221323B2
公开(公告)日：2012-07-17
申请号：US11833502
申请日：2007-08-03
申请人： Yunlong Zhang , Yongxing Zhang , Paul E. Zarembo
发明人： Yunlong Zhang , Yongxing Zhang , Paul E. Zarembo
IPC分类号： A61B8/00
CPC分类号： A61B8/12 , A61B5/0031 , A61B5/08 , A61B5/4878 , A61B8/4472
摘要： Systems and methods for monitoring lung edema fluid status, such as monitoring the presence or absence of pulmonary edema, in a subject using information about responsive acoustic energy echoes from a lung are described. The system comprises, among other things, an implantable device including an acoustic transducer configured to emit acoustic energy to a lung and to receive one or more responsive acoustic energy echoes from a lung. In an example, the implantable device includes a cardiac function management device having an acoustic window in a body thereof. In another example, the implantable device includes one or more subcutaneous leads. An implantable or external processor circuit is configured to receive information about the acoustic energy echoes to compute and provide a lung edema fluid status indication; such information may include an increased number or special pattern of acoustic energy echoes received or a decreased time between successively received echoes.
摘要翻译： 描述了使用关于来自肺的响应性声能回波的信息来监测受试者肺水肿液体状态的系统和方法，例如监测受试者是否存在肺水肿。 除其他之外，该系统包括可植入装置，其包括被配置为向肺发出声能并且接收来自肺的一个或多个响应声能回波的声学换能器。 在一个示例中，可植入装置包括其身体中具有声窗口的心脏功能管理装置。 在另一示例中，可植入装置包括一个或多个皮下引线。 植入式或外部处理器电路被配置为接收关于声能回波的信息，以计算并提供肺水肿状态指示; 这样的信息可以包括接收的声能回波的增加的数量或特殊模式或连续接收的回波之间的减少的时间。
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公开(公告)号：US20080262586A1
公开(公告)日：2008-10-23
申请号：US12144247
申请日：2008-06-23
IPC分类号： A61N1/05
CPC分类号： A61N1/057 , A61N1/056 , A61N2001/0585
摘要： A pacing lead having a lead body configured into a pre-formed J-shape. The lead includes a pacing electrode coupled to an intermediate portion of the lead body and located distally from a bottom of the pre-formed J-shape. The lead is adapted to be placed within a heart in a J-shaped configuration with the electrode positioned proximate a ventricular septum or a right ventricular outflow tract such that at least a portion of the distal end of the lead body is located within a pulmonary artery. In one embodiment, the distal end of the lead is configured to be passively fixated within the pulmonary artery. Another aspect includes a lead body wherein a section of the intermediate portion of the lead body is less stiff than adjacent sections of the lead body. The lead includes a pacing electrode coupled to the intermediate portion of the lead body and located distally from the less stiff section. The lead is adapted to be placed within a heart in a J-shaped configuration with the less stiff section near a bottom of the J-shape such that the electrode is positioned proximate a ventricular septum or a right ventricular outflow tract and at least a portion of the distal end of the lead body is fixated within a pulmonary artery.
摘要翻译： 具有构造成预成形的J形的引线主体的起搏引线。 引线包括连接到引线主体的中间部分并且位于远离预成形的J形的底部的起搏电极。 引线适于放置在J形构型的心脏内，其中电极位于心室隔膜或右心室流出道附近，使得引线体的远端的至少一部分位于肺动脉内 。 在一个实施例中，引线的远端构造成被动地固定在肺动脉内。 另一方面包括引线体，其中引线主体的中间部分的部分比引线本体的相邻部分刚性差。 引线包括连接到引线主体的中间部分并位于较不硬的部分的远侧的起搏电极。 引线适于放置在心脏内的J形构型中，具有靠近J形底部的较硬的部分，使得电极位于靠近心室隔膜或右心室流出道和至少一部分 引导体的远端固定在肺动脉内。
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6.发明授权Implantable lead for septal placement of electrode with fixation mechanism in the pulmonary artery 失效在肺动脉中具有固定机制的电极间隔放置的植入性铅公开(公告)号：US07890188B2
公开(公告)日：2011-02-15
申请号：US10325658
申请日：2002-12-19
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61N1/057 , A61N2001/0585
摘要： A lead body includes an electrode coupled to an intermediate portion of the lead body. A distal end of the lead includes a pre-formed, biased shape adapted to passively fixate the distal end of the lead within a pulmonary artery with the electrode positioned in the right ventricle or ventricular outflow tract. The lead body can include a preformed J-shape, with the electrode coupled to the intermediate portion of the lead body and located distally from a bottom of the pre-formed J-shape. The lead body can include a section of the intermediate portion of the lead body being less stiff than adjacent sections of the lead body with the electrode coupled to the intermediate portion of the lead body and located distally from the less stiff section.
摘要翻译： 引线体包括连接到引线主体的中间部分的电极。 引线的远端包括预先形成的偏压形状，其适于被动地固定在肺动脉内的引线的远端，其中电极定位在右心室或心室流出道中。 引线体可以包括预成型的J形，电极耦合到引线本体的中间部分并且位于远离预成形的J形的底部。 引线主体可以包括引线主体的中间部分的一部分比引线主体的相邻部分刚性差，其中电极耦合到引线主体的中间部分并且位于较硬的部分的远侧。
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公开(公告)号：US08204606B2
公开(公告)日：2012-06-19
申请号：US12144247
申请日：2008-06-23
IPC分类号： A61N1/05
CPC分类号： A61N1/057 , A61N1/056 , A61N2001/0585
摘要： A pacing lead having a lead body configured into a pre-formed J-shape. The lead includes a pacing electrode coupled to an intermediate portion of the lead body and located distally from a bottom of the pre-formed J-shape. The lead is adapted to be placed within a heart in a J-shaped configuration with the electrode positioned proximate a ventricular septum or a right ventricular outflow tract such that at least a portion of the distal end of the lead body is located within a pulmonary artery. In one embodiment, the distal end of the lead is configured to be passively fixated within the pulmonary artery. Another aspect includes a lead body wherein a section of the intermediate portion of the lead body is less stiff than adjacent sections of the lead body. The lead includes a pacing electrode coupled to the intermediate portion of the lead body and located distally from the less stiff section. The lead is adapted to be placed within a heart in a J-shaped configuration with the less stiff section near a bottom of the J-shape such that the electrode is positioned proximate a ventricular septum or a right ventricular outflow tract and at least a portion of the distal end of the lead body is fixated within a pulmonary artery.
摘要翻译： 具有构造成预成形的J形的引线主体的起搏引线。 引线包括连接到引线主体的中间部分并且位于远离预成形的J形的底部的起搏电极。 引线适于放置在J形构型的心脏内，其中电极位于心室隔膜或右心室流出道附近，使得引线体的远端的至少一部分位于肺动脉内 。 在一个实施例中，引线的远端构造成被动地固定在肺动脉内。 另一方面包括引线体，其中引线主体的中间部分的部分比引线本体的相邻部分刚性差。 引线包括连接到引线主体的中间部分并位于较不硬的部分的远侧的起搏电极。 引线适于放置在心脏内的J形构型中，具有靠近J形底部的较硬的部分，使得电极位于靠近心室隔膜或右心室流出道和至少一部分 引导体的远端固定在肺动脉内。
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公开(公告)号：US07072703B2
公开(公告)日：2006-07-04
申请号：US10429180
申请日：2003-04-30
CPC分类号： A61B90/06 , A61B2090/064 , A61N1/08
摘要： A medical device for use with an implantable lead includes a force monitoring system coupled with the device. The force monitoring system monitors force placed on the medical device and/or the lead. Optionally the system compares the force with a preset limit, and notifies a user once the preset limit has been reached.
摘要翻译： 用于可植入引线的医疗装置包括与该装置耦合的力监测系统。 力监测系统监测放在医疗设备和/或引线上的力。 可选地，系统将力与预设限制进行比较，一旦达到预设限制，就通知用户。
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公开(公告)号：US20090036777A1
公开(公告)日：2009-02-05
申请号：US11833502
申请日：2007-08-03
申请人： Yunlong Zhang , Yongxing Zhang , Paul E. Zarembo
发明人： Yunlong Zhang , Yongxing Zhang , Paul E. Zarembo
IPC分类号： A61B8/00
CPC分类号： A61B8/12 , A61B5/0031 , A61B5/08 , A61B5/4878 , A61B8/4472
摘要： Systems and methods for monitoring lung edema fluid status, such as monitoring the presence or absence of pulmonary edema, in a subject using information about responsive acoustic energy echoes from a lung are described. The system comprises, among other things, an implantable device including an acoustic transducer configured to emit acoustic energy to a lung and to receive one or more responsive acoustic energy echoes from a lung. In an example, the implantable device includes a cardiac function management device having an acoustic window in a body thereof. In another example, the implantable device includes one or more subcutaneous leads. An implantable or external processor circuit is configured to receive information about the acoustic energy echoes to compute and provide a lung edema fluid status indication; such information may include an increased number or special pattern of acoustic energy echoes received or a decreased time between successively received echoes.
摘要翻译： 描述了使用关于来自肺的响应性声能回波的信息来监测受试者肺水肿液体状态的系统和方法，例如监测受试者是否存在肺水肿。 除其他之外，该系统包括可植入装置，其包括被配置为向肺发出声能并且接收来自肺的一个或多个响应声能回波的声学换能器。 在一个示例中，可植入装置包括其身体中具有声窗口的心脏功能管理装置。 在另一示例中，可植入装置包括一个或多个皮下引线。 植入式或外部处理器电路被配置为接收关于声能回波的信息，以计算并提供肺水肿状态指示; 这样的信息可以包括接收的声能回波的增加的数量或特殊模式或连续接收的回波之间的减少的时间。
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公开(公告)号：US07392094B2
公开(公告)日：2008-06-24
申请号：US10325433
申请日：2002-12-19
IPC分类号： A61N1/05
CPC分类号： A61N1/057 , A61N1/056 , A61N2001/0585
摘要： A pacing lead having a lead body configured into a pre-formed J-shape. The lead includes a pacing electrode coupled to an intermediate portion of the lead body and located distally from a bottom of the pre-formed J-shape. The lead is adapted to be placed within a heart in a J-shaped configuration with the electrode positioned proximate a ventricular septum or a right ventricular outflow tract such that at least a portion of the distal end of the lead body is located within a pulmonary artery. In one embodiment, the distal end of the lead is configured to be passively fixated within the pulmonary artery. Another aspect includes a lead body wherein a section of the intermediate portion of the lead body is less stiff than adjacent sections of the lead body. The lead includes a pacing electrode coupled to the intermediate portion of the lead body and located distally from the less stiff section. The lead is adapted to be placed within a heart in a J-shaped configuration with the less stiff section near a bottom of the J-shape such that the electrode is positioned proximate a ventricular septum or a right ventricular outflow tract and at least a portion of the distal end of the lead body is fixated within a pulmonary artery.
摘要翻译： 具有构造成预成形的J形的引线主体的起搏引线。 引线包括连接到引线主体的中间部分并且位于远离预成形的J形的底部的起搏电极。 引线适于放置在J形构型的心脏内，其中电极位于心室隔膜或右心室流出道附近，使得引线体的远端的至少一部分位于肺动脉内 。 在一个实施例中，引线的远端构造成被动地固定在肺动脉内。 另一方面包括引线体，其中引线主体的中间部分的部分比引线本体的相邻部分刚性差。 引线包括连接到引线主体的中间部分并位于较不硬的部分的远侧的起搏电极。 引线适于放置在心脏内的J形构型中，具有靠近J形底部的较硬的部分，使得电极位于靠近心室隔膜或右心室流出道和至少一部分 引导体的远端固定在肺动脉内。
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