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    Blood pressure monitoring in noisy environments
    1.
    发明授权
    Blood pressure monitoring in noisy environments 失效
    嘈杂环境中的血压监测

    公开(公告)号：US5392781A

    公开(公告)日：1995-02-28

    申请号：US686420

    申请日：1991-04-16

    申请人： Patrick G. Phillipps ,  Paul Epstein ,  David G. Tweed

    发明人： Patrick G. Phillipps ,  Paul Epstein ,  David G. Tweed

    IPC分类号： A61B5/022 ,  A61B5/02 ,  A61B5/0225

    CPC分类号： A61B5/02208 ,  A61B5/02

    摘要： Several techniques are provided for aiding in the discrimination of detected biological signals indicative of blood pressure from detected signals not indicative of blood pressure (e.g., noise). A threshold, based predominantly on a level of noise, is developed and used in the discrimination. A second threshold, based predominantly on levels of previously detected biological signals, is developed and additionally used to help discriminate the biological signals from noise. The biological signals are detected during a selected portion of a cardiac cycle, and additional signals detected outside of the selected portion of the cycle are applied to the detected signals. Another threshold may be developed based predominantly on a level of signals sensed by a transducer positioned to preferentially sense noise; the transducer is positioned so that the noise that it detects is related to noise that is detected during the detection of the biological signals. Blood pressure is measured during periodically scheduled measurement cycles, and a measurement cycle is suspended if noise exceeds a predetermined level. The times at which the detected signals (i.e., the signals indicative of blood pressure and the signals not indicative of blood pressure) are processed during a given cardiac cycle are selected based at least in part on the pressure of the cuff. The biological signals indicative of blood pressure that are detected during a current measurement cycle are used to at least in part determine the times at which the detected signals will be processed during a succeeding measurement cycle.

    摘要翻译： 提供了几种技术来帮助鉴别从未指示血压（例如，噪声）的检测信号指示血压的检测到的生物信号。 基于噪音水平的阈值主要用于歧视。 开发了主要基于先前检测到的生物信号的水平的第二阈值，并且另外用于帮助区分生物信号与噪声。 在心脏周期的选定部分期间检测生物信号，并且在周期的选定部分之外检测到的附加信号被应用于检测到的信号。 可以主要基于被定位成优先感测噪声的换能器感测的信号的水平来开发另一个阈值; 换能器被定位成使得其检测到的噪声与在生物信号的检测期间检测到的噪声相关。 在周期性调度的测量循环期间测量血压，并且如果噪声超过预定水平，则测量循环被暂停。 至少部分地基于袖带的压力选择在给定的心动周期期间处理检测到的信号（即，指示血压的信号和不指示血压的信号）的时间。 指示在当前测量周期期间检测到的血压的生物信号用于至少部分地确定在随后的测量周期期间检测到的信号将被处理的时间。

    Remotely programmable infusion system
    2.
    再颁专利
    Remotely programmable infusion system 失效

    公开(公告)号：USRE36871E

    公开(公告)日：2000-09-12

    申请号：US401339

    申请日：1995-03-09

    申请人： Paul Epstein ,  Harry Petschek ,  Eric LaWhite ,  Clair Strohl ,  Henry Coyne ,  Edward Kaleskas ,  George Adaniya

    发明人： Paul Epstein ,  Harry Petschek ,  Eric LaWhite ,  Clair Strohl ,  Henry Coyne ,  Edward Kaleskas ,  George Adaniya

    IPC分类号： A61M5/00 ,  A61M5/142 ,  A61M5/168 ,  A61M5/172 ,  A61M31/00

    CPC分类号： A61M5/14224 ,  A61M5/172 ,  A61M2005/14208 ,  A61M5/16827 ,  Y10S128/13

    摘要： An infusion system for administering multiple infusates at individually programmable rates, volumes, and sequences in any order from any one or more of plural fluid input ports through a patient output port and into the circulatory system of a patient. Infusates may be either continuously or time sequentially administered, and infusates may be either intermittently administered at selectively regular intervals or in time overlap to administer a dilution. Various error conditions are automatically detected and alarms generated in the event of conflicts between infusates, to identify times of no infusions, and to identify system malfunctions. The system is selectively operable, among others, in a priming mode, a maintenance mode, a normal-on mode, and a manual override mode. The system is operative to adapt actual to desired flow rates in normal operation. All fluids flow through a unitary disposable cassette without making any other system contact. Air bubbles in the fluid line are automatically detected and disposed of. Fluid pressures are monitored and system operation adjusted as a function of such pressures. Infusates may be administered from syringes as well as from standard bag or bottle containers. Infusate from a selected input port may be controllably pumped into a syringe for unsticking the syringe plunger. The system is selectively operable to adjust total fluid volume and rate to below preselected values for patients whose total fluid intake must be restricted. The system is operable to maintain an accurate record of total infusion history. The system may be controlled by a terminal or a computer located remotely from the patient location. The system may include auxiliary pumps in addition to a primary pump, all controlled by a single computer.

    Infusion system having plural fluid input ports and at least one patient output port
    7.
    发明授权
    Infusion system having plural fluid input ports and at least one patient output port 失效
    具有多个流体输入端口和至少一个患者输出端口的输液系统

    公开(公告)号：US5464392A

    公开(公告)日：1995-11-07

    申请号：US207281

    申请日：1994-03-07

    申请人： Paul Epstein ,  Harry Petschek ,  Eric LaWhite ,  Clair Strohl ,  Henry Coyne ,  Edward Kaleskas ,  George Adaniva

    发明人： Paul Epstein ,  Harry Petschek ,  Eric LaWhite ,  Clair Strohl ,  Henry Coyne ,  Edward Kaleskas ,  George Adaniva

    IPC分类号： A61M5/142 ,  A61M5/168 ,  A61M5/172 ,  A61M31/00

    CPC分类号： A61M5/172 ,  A61M5/14224 ,  A61M2005/1402 ,  A61M2005/14208 ,  A61M5/16827 ,  Y10S128/12 ,  Y10S128/13

    摘要： An infusion system for administering multiple infusates at individually programmable rates, volumes, and sequences in any order from any one or more of plural fluid input ports through a patient output port and into the circulatory system of a patient. Infusates may be either continuously or time sequentially administered, and infusates may be either intermittently administered at selectively regular intervals or in time overlap to administer a dilution. Various error conditions are automatically detected and alarms generated in the event of conflicts between infusates, to identify times of no infusions, and to identify system malfunctions. The system is selectively operable, among others, in a priming mode, a maintenance mode, a normal-on mode, and a manual override mode, The system is operative to adapt actual to desired flow rates in normal operation. All fluids flow through a unitary disposable cassette without making any other system contact. Air bubbles in the fluid line are automatically detected and disposed of. Fluid pressures are monitored and system operation adjusted as a function of such pressures. Infusates may be administered from syringes as well as from standard bag or bottle containers. Infusate from a selected input port may be controllably pumped into a syringe for unsticking the syringe plunger. The system is selectively operable to adjust total fluid volume and rate to below preselected values for patients whose total fluid intake must be restricted. The system is operable to maintain an accurate record of total infusion history.

    摘要翻译： 一种输注系统，用于以多个流体输入端口中的任何一个或多个通过患者输出端口并进入患者的循环系统，以单独可编程的速率，体积和顺序管理多个输注物。 输注物可以是连续的或时间依次施用的，并且输注物可以间歇地以选择性的定期间隔或时间重叠施用以施用稀释。 自动检测各种错误条件，并在发生冲突时产生警报，识别不输注的时间，并识别系统故障。 系统可以选择性地操作，其中包括启动模式，维护模式，正常模式和手动超控模式。该系统可操作以在正常操作中使实际与期望流量相适应。 所有的流体都流经整体的一次性盒式磁带，而不会使任何其他系统接触。 流体管路中的气泡被自动检测并处理。 监测流体压力并根据这种压力调整系统运行。 注射器可以从注射器以及标准袋或瓶容器中进行施用。 从选择的输入端口输注可以可控地泵送到注射器中用于取消对注射器柱塞的取出。 该系统可选择性地可操作地调整总体积体积并且对于总流体摄取必须被限制的患者的速率低于预选值。 该系统可操作以保持总输液历史的准确记录。

    Pressure responsive multiple input infusion system
    8.
    发明授权
    Pressure responsive multiple input infusion system 失效
    压力响应多输入输液系统

    公开(公告)号：US5108367A

    公开(公告)日：1992-04-28

    申请号：US682871

    申请日：1991-04-08

    申请人： Paul Epstein ,  Harry Petschek ,  Eric LaWhite ,  Clair Strohl ,  Henry Coyne ,  Edward Kaleskas ,  George Adaniva

    发明人： Paul Epstein ,  Harry Petschek ,  Eric LaWhite ,  Clair Strohl ,  Henry Coyne ,  Edward Kaleskas ,  George Adaniva

    IPC分类号： A61M5/142 ,  A61M5/168 ,  A61M5/172

    CPC分类号： A61M5/14224 ,  A61M5/172 ,  A61M2005/1402 ,  A61M2005/14208 ,  A61M5/16827 ,  Y10S128/12

    摘要： An infusion system for administering multiple infusates at individually programmable rates, volumes, and sequences in any order from any one or more of plural fluid input ports through a patient output port and into the circulatory system of a patient. Infusates may be either continuously or time sequentially administered, and infusates may be either intermittently administered at selectively regular intervals or in time overlap to administer a dilution. Various error conditions are automatically detected and alarms generated in the event of conflicts between infusates, to identify times of no infusions, and to identify system malfunctions. The system is selectively operable, among others, in a priming mode, a maintenance mode, a normal-on mode, and a manual override mode. The system is operative to adapt actual to desired flow rates in normal operation. All fluids flow through a unitary disposable cassette without making any other system contact. Air bubbles in the fluid line are automatically detected and disposed of. Fluid pressures are monitored and system operation adjusted as a function of such pressures. Infusates may be administered from syringes as well as from standard bag or bottle containers. Infusate from a selected input port may be controllably pumped into a syringe for unsticking the syringe plunger. The system is selectively operable to adjust total fluid volume and rate to below preselected values for patients whose total intake must be restricted. The system is operable to maintain an accurate record of total infusion history.

    摘要翻译： 一种输注系统，用于以多个流体输入端口中的任何一个或多个通过患者输出端口并进入患者的循环系统，以单独可编程的速率，体积和顺序管理多个输注物。 输注物可以是连续的或时间依次施用的，并且输注物可以间歇地以选择性的定期间隔或时间重叠施用以施用稀释。 自动检测各种错误条件，并在发生冲突时产生警报，识别不输注的时间，并识别系统故障。 该系统可以选择性地可操作地在启动模式，维护模式，正常模式和手动超控模式中。 该系统可操作以在正常操作中使实际适应期望的流速。 所有的流体都流经整体的一次性盒式磁带，而不会使任何其他系统接触。 流体管路中的气泡被自动检测并处理。 监测流体压力并根据这种压力调整系统运行。 注射器可以从注射器以及标准袋或瓶容器中进行施用。 从选择的输入端口输注可以可控地泵送到注射器中用于取消对注射器柱塞的取出。 该系统可选择性地可操作地调整总体积体积并且对总入血量必须限制的患者的速率低于预选值。 该系统可操作以保持总输液历史的准确记录。

    Electronically augmented stethoscope with timing sound
    9.
    发明授权
    Electronically augmented stethoscope with timing sound 失效
    电子增强听诊器与定时声音

    公开(公告)号：US5003605A

    公开(公告)日：1991-03-26

    申请号：US393781

    申请日：1989-08-14

    申请人： Patrick G. Phillipps ,  Paul Epstein ,  David G. Tweed

    发明人： Patrick G. Phillipps ,  Paul Epstein ,  David G. Tweed

    IPC分类号： A61B5/022 ,  A61B5/025 ,  A61B5/0408 ,  A61B5/0456 ,  A61B7/02 ,  A61B7/04

    CPC分类号： A61B7/02 ,  A61B5/04085 ,  A61B5/0456

    摘要： A stethoscope, operable in an acoustic or electronically augmented mode, is disclosed. In one electronically augmented mode of operation, the stethoscope simultaneously provides the listener with combined unmodified, familiar audible sounds and sounds which have been electronically augmented to bring them within the human auditory range. Additionally, a timing sound may be provided along with the unmodified, familiar audible sounds and electronically augmented sounds to assist the listener in determining when sounds occur in the heart cycle. The timing sound may be enabled in the acoustic mode of stethoscope operation so that the listener can place familiar audible sounds within the heart cycle.

    摘要翻译： 公开了一种以声学或电子增强模式操作的听诊器。 在一种电子增强操作模式中，听诊器同时向聆听者提供组合的未修改的，熟悉的可听见的声音和声音，这些声音和声音已被电子增强以将它们带入人的听觉范围。 此外，可以提供定时声音以及未修改的熟悉的可听见的声音和电子增强的声音，以帮助听众确定在心脏周期中何时出现声音。 在听诊器操作的声学模式中，定时声音可以被使能，从而听众可以在心脏周期内放置熟悉的声音。