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公开(公告)号：US08084417B2
公开(公告)日：2011-12-27
申请号：US12214554
申请日：2008-06-19
申请人： Daniel Marquess , Martin S. Linsell , S. Derek Turner , Sean G. Trapp , Daniel D. Long , Paul R. Fatheree
发明人： Daniel Marquess , Martin S. Linsell , S. Derek Turner , Sean G. Trapp , Daniel D. Long , Paul R. Fatheree
IPC分类号： A61K38/14
CPC分类号： C07K9/008 , A61K38/00 , Y02A50/473
摘要： This invention provides cross-linked glycopeptide-cephalosporin compounds and pharmaceutically acceptable salts thereof which are useful as antibiotics. This invention also provides pharmaceutical compositions containing such compounds; methods for treating bacterial infections in a mammal using such compounds; and processes and intermediates useful for preparing such compounds.
摘要翻译： 本发明提供可用作抗生素的交联糖肽 - 头孢菌素化合物及其药学上可接受的盐。 本发明还提供含有这些化合物的药物组合物; 使用这些化合物治疗哺乳动物细菌感染的方法; 以及可用于制备这些化合物的方法和中间体。
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公开(公告)号：US07612037B2
公开(公告)日：2009-11-03
申请号：US11977604
申请日：2007-10-25
申请人： Paul R. Fatheree , Martin S. Linsell , Daniel D. Long , Daniel Marquess , Edmund J. Moran , Matthew B. Nodwell , S. Derek Turner , James Aggen
发明人： Paul R. Fatheree , Martin S. Linsell , Daniel D. Long , Daniel Marquess , Edmund J. Moran , Matthew B. Nodwell , S. Derek Turner , James Aggen
CPC分类号： A61K31/545 , A61K38/00 , C07D277/40 , C07D277/42 , C07D407/12 , C07D407/14 , C07D501/00 , C07D501/46 , C07K9/008
摘要： This invention provides cross-linked glycopeptide-cephalosporin compounds and pharmaceutically acceptable salts thereof which are useful as antibiotics. This invention also provides pharmaceutical compositions containing such compounds; methods for treating bacterial infections in a mammal using such compounds; and processes and intermediates useful for preparing such compounds.
摘要翻译： 本发明提供可用作抗生素的交联糖肽 - 头孢菌素化合物及其药学上可接受的盐。 本发明还提供含有这些化合物的药物组合物; 使用这些化合物治疗哺乳动物细菌感染的方法; 以及可用于制备这些化合物的方法和中间体。
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公开(公告)号：US07553962B2
公开(公告)日：2009-06-30
申请号：US11895369
申请日：2007-08-24
IPC分类号： C07D501/56 , C07D501/24 , C07D277/40 , C07D277/42 , C07D277/46 , C07K9/00 , A61K38/14 , A61P31/04
CPC分类号： A61K31/545 , A61K38/00 , C07D277/40 , C07D277/42 , C07D407/12 , C07D407/14 , C07D501/00 , C07D501/46 , C07K9/008
摘要： This invention provides cross-linked glycopeptide-cephalosporin compounds and pharmaceutically acceptable salts thereof which are useful as antibiotics. This invention also provides pharmaceutical compositions containing such compounds; methods for treating bacterial infections in a mammal using such compounds; and processes and intermediates useful for preparing such compounds.
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公开(公告)号：US07728127B2
公开(公告)日：2010-06-01
申请号：US11895534
申请日：2007-08-24
IPC分类号： C07D501/00 , A61K38/66 , A61K31/545 , A61K38/00 , C12Q1/12 , C12P35/06 , G01N33/06
CPC分类号： A61K31/545 , A61K38/00 , C07D277/40 , C07D277/42 , C07D407/12 , C07D407/14 , C07D501/00 , C07D501/46 , C07K9/008
摘要： This invention provides cross-linked glycopeptide-cephalosporin compounds and pharmaceutically acceptable salts thereof which are useful as antibiotics. This invention also provides pharmaceutical compositions containing such compounds; methods for treating bacterial infections in a mammal using such compounds; and processes and intermediates useful for preparing such compounds.
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公开(公告)号：US20080194464A1
公开(公告)日：2008-08-14
申请号：US11895531
申请日：2007-08-24
申请人： Paul R. Fatheree , Martin S. Linsell , Daniel D. Long , Daniel Marquess , Edmund J. Moran , Matthew B. Nodwell , S. Derek Turner , James Aggen
发明人： Paul R. Fatheree , Martin S. Linsell , Daniel D. Long , Daniel Marquess , Edmund J. Moran , Matthew B. Nodwell , S. Derek Turner , James Aggen
CPC分类号： A61K31/545 , A61K38/00 , C07D277/40 , C07D277/42 , C07D407/12 , C07D407/14 , C07D501/00 , C07D501/46 , C07K9/008
摘要： This invention provides cross-linked glycopeptide-cephalosporin compounds and pharmaceutically acceptable salts thereof which are useful as antibiotics. This invention also provides pharmaceutical compositions containing such compounds; methods for treating bacterial infections in a mammal using such compounds; and processes and intermediates useful for preparing such compounds.
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公开(公告)号：US07341993B2
公开(公告)日：2008-03-11
申请号：US11172303
申请日：2005-06-30
申请人： Paul R. Fatheree , Martin S. Linsell , Daniel D. Long , Daniel Marquess , Edmund J. Moran , Matthew B. Nodwell , S. Derek Turner , James Aggen
发明人： Paul R. Fatheree , Martin S. Linsell , Daniel D. Long , Daniel Marquess , Edmund J. Moran , Matthew B. Nodwell , S. Derek Turner , James Aggen
CPC分类号： A61K31/545 , A61K38/00 , C07D277/40 , C07D277/42 , C07D407/12 , C07D407/14 , C07D501/00 , C07D501/46 , C07K9/008
摘要： This invention provides cross-linked glycopeptide-cephalosporin compounds and pharmaceutically acceptable salts thereof which are useful as antibiotics. This invention also provides pharmaceutical compositions containing such compounds; methods for treating bacterial infections in a mammal using such compounds; and processes and intermediates useful for preparing such compounds.
摘要翻译： 本发明提供可用作抗生素的交联糖肽 - 头孢菌素化合物及其药学上可接受的盐。 本发明还提供含有这些化合物的药物组合物; 使用这些化合物治疗哺乳动物细菌感染的方法; 以及可用于制备这些化合物的方法和中间体。
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公开(公告)号：US06878686B2
公开(公告)日：2005-04-12
申请号：US10444847
申请日：2003-05-23
申请人： Daniel Marquess , Martin S. Linsell , S. Derek Turner , Sean G. Trapp , Daniel D. Long , Paul R. Fatheree
发明人： Daniel Marquess , Martin S. Linsell , S. Derek Turner , Sean G. Trapp , Daniel D. Long , Paul R. Fatheree
CPC分类号： C07K9/008 , A61K38/00 , Y02A50/473
摘要： This invention provides cross-linked glycopeptide-cephalosporin compounds and pharmaceutically acceptable salts thereof which are useful as antibiotics. This invention also provides pharmaceutical compositions containing such compounds; methods for treating bacterial infections in a mammal using such compounds; and processes and intermediates useful for preparing such compounds.
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公开(公告)号：US20100197569A1
公开(公告)日：2010-08-05
申请号：US12759073
申请日：2010-04-13
申请人： Paul R. Fatheree , Martin S. Linsell , Daniel D. Long , Daniel Marquess , Edmund J. Moran , Matthew B. Nodwell , S. Derek Turner , James Aggen
发明人： Paul R. Fatheree , Martin S. Linsell , Daniel D. Long , Daniel Marquess , Edmund J. Moran , Matthew B. Nodwell , S. Derek Turner , James Aggen
IPC分类号： A61K38/14 , C07K9/00 , C07D501/16 , C07D277/38 , A61P31/04 , A01N37/18 , C07K1/113
CPC分类号： A61K31/545 , A61K38/00 , C07D277/40 , C07D277/42 , C07D407/12 , C07D407/14 , C07D501/00 , C07D501/46 , C07K9/008
摘要： This invention provides cross-linked glycopeptide—cephalosporin compounds and pharmaceutically acceptable salts thereof which are useful as antibiotics. This invention also provides pharmaceutical compositions containing such compounds; methods for treating bacterial infections in a mammal using such compounds; and processes and intermediates useful for preparing such compounds.
摘要翻译： 本发明提供可用作抗生素的交联糖肽 - 头孢菌素化合物及其药学上可接受的盐。 本发明还提供含有这些化合物的药物组合物; 使用这种化合物治疗哺乳动物细菌感染的方法; 以及可用于制备这些化合物的方法和中间体。
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公开(公告)号：US07713931B2
公开(公告)日：2010-05-11
申请号：US11895533
申请日：2007-08-24
CPC分类号： A61K31/545 , A61K38/00 , C07D277/40 , C07D277/42 , C07D407/12 , C07D407/14 , C07D501/00 , C07D501/46 , C07K9/008
摘要： This invention provides cross-linked glycopeptide-cephalosporin compounds and pharmaceutically acceptable salts thereof which are useful as antibiotics. This invention also provides pharmaceutical compositions containing such compounds; methods for treating bacterial infections in a mammal using such compounds; and processes and intermediates useful for preparing such compounds.
摘要翻译： 本发明提供可用作抗生素的交联糖肽 - 头孢菌素化合物及其药学上可接受的盐。 本发明还提供含有这些化合物的药物组合物; 使用这些化合物治疗哺乳动物细菌感染的方法; 以及可用于制备这些化合物的方法和中间体。
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公开(公告)号：US07655621B2
公开(公告)日：2010-02-02
申请号：US11895555
申请日：2007-08-24
CPC分类号： A61K31/545 , A61K38/00 , C07D277/40 , C07D277/42 , C07D407/12 , C07D407/14 , C07D501/00 , C07D501/46 , C07K9/008
摘要： This invention provides cross-linked glycopeptide-cephalosporin compounds and pharmaceutically acceptable salts thereof which are useful as antibiotics. This invention also provides pharmaceutical compositions containing such compounds; methods for treating bacterial infections in a mammal using such compounds; and processes and intermediates useful for preparing such compounds.
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