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    Systems and methods for analyzing a physiological sensor signal
    1.
    发明授权
    Systems and methods for analyzing a physiological sensor signal 有权

    公开(公告)号：US09770210B2

    公开(公告)日：2017-09-26

    申请号：US13243619

    申请日：2011-09-23

    申请人： Paul S. Addison ,  James Watson

    发明人： Paul S. Addison ,  James Watson

    IPC分类号： A61B5/00 ,  A61B5/1455

    CPC分类号： A61B5/7221 ,  A61B5/14551

    摘要： The present disclosure relates generally to patient monitoring systems and, more particularly, to signal analysis for patient monitoring systems. In one embodiment, a method of analyzing a detector signal of a physiological patient sensor includes obtaining the detector signal from the physiological patient sensor, wherein the detector signal crosses a horizontal boundary more than once. The method also includes determining the relative time and the slope of the detector signal at each boundary crossing. The method further includes estimating the amplitude of the detector signal based, at least in part, on the determined relative time and slope of the detector signal at each boundary crossing. The method also includes determining a physiological parameter of a patient based, at least in part, on the estimate of the amplitude of the detector signal.

    Pulse Rate Determination Using Gaussian Kernel Smoothing of Multiple Inter-Fiducial Pulse Periods
    2.
    发明申请
    Pulse Rate Determination Using Gaussian Kernel Smoothing of Multiple Inter-Fiducial Pulse Periods 有权
    使用高斯核平滑多个基准脉冲周期的脉冲速率确定

    公开(公告)号：US20130137945A1

    公开(公告)日：2013-05-30

    申请号：US13307453

    申请日：2011-11-30

    申请人： Paul S. Addison ,  James Watson

    发明人： Paul S. Addison ,  James Watson

    IPC分类号： A61B5/1455 ,  A61B5/00

    CPC分类号： A61B5/02416 ,  A61B5/024 ,  A61B5/725

    摘要： Systems and methods are provided for determining the pulse rate of a patient from multiple fiducial points using Gaussian kernel smoothing. Based on acquired pleth signals, each recorded fiducial pulse period is converted to a Gaussian kernel function. The Gaussian kernel functions for all recorded fiducial points are summed to generate a Gaussian kernel smoothed curve. The pulse rate of a patient may be determined from the Gaussian kernel smoothed curve. All acquired fiducial pulse periods contribute to generate the Gaussian kernel smoothing curve. The number of fiducial points utilized may change to improve pulse rate determination or provide additional functionality to the system.

    摘要翻译： 提供了系统和方法，用于使用高斯核平滑从多个基准点确定患者的脉搏率。 基于获取的信号，将每个记录的基准脉冲周期转换为高斯核函数。 将所有记录的基准点的高斯核函数相加，生成高斯核平滑曲线。 可以从高斯核平滑曲线确定患者的脉率。 所有获得的基准脉冲周期有助于生成高斯核平滑曲线。 所使用的基准点的数量可以改变以改善脉搏率确定或者为系统提供额外的功能。

    SYSTEMS AND METHODS FOR ANALYZING A PHYSIOLOGICAL SENSOR SIGNAL
    3.
    发明申请
    SYSTEMS AND METHODS FOR ANALYZING A PHYSIOLOGICAL SENSOR SIGNAL 有权
    用于分析生理传感器信号的系统和方法

    公开(公告)号：US20130079601A1

    公开(公告)日：2013-03-28

    申请号：US13243619

    申请日：2011-09-23

    申请人： Paul S. Addison ,  James Watson

    发明人： Paul S. Addison ,  James Watson

    IPC分类号： A61B5/00 ,  G06F19/00

    CPC分类号： A61B5/7221 ,  A61B5/14551

    摘要： The present disclosure relates generally to patient monitoring systems and, more particularly, to signal analysis for patient monitoring systems. In one embodiment, a method of analyzing a detector signal of a physiological patient sensor includes obtaining the detector signal from the physiological patient sensor, wherein the detector signal crosses a horizontal boundary more than once. The method also includes determining the relative time and the slope of the detector signal at each boundary crossing. The method further includes estimating the amplitude of the detector signal based, at least in part, on the determined relative time and slope of the detector signal at each boundary crossing. The method also includes determining a physiological parameter of a patient based, at least in part, on the estimate of the amplitude of the detector signal.

    摘要翻译： 本公开一般涉及患者监视系统，更具体地，涉及用于患者监视系统的信号分析。 在一个实施例中，分析生理学患者传感器的检测器信号的方法包括从生理患者传感器获得检测器信号，其中检测器信号多次跨越水平边界。 该方法还包括确定每个边界处的检测器信号的相对时间和斜率。 该方法还包括至少部分地基于所确定的每个边界处的检测器信号的相对时间和斜率来估计检测器信号的幅度。 该方法还包括至少部分地基于检测器信号的幅度的估计来确定患者的生理参数。

    VENOUS OXYGEN SATURATION SYSTEMS AND METHODS
    4.
    发明申请
    VENOUS OXYGEN SATURATION SYSTEMS AND METHODS 有权

    公开(公告)号：US20130066174A1

    公开(公告)日：2013-03-14

    申请号：US13229458

    申请日：2011-09-09

    申请人： Paul S. Addison ,  James Watson ,  James Ochs ,  Scott McGonigle

    发明人： Paul S. Addison ,  James Watson ,  James Ochs ,  Scott McGonigle

    IPC分类号： A61B5/1455

    CPC分类号： A61B5/14551 ,  A61B5/7207 ,  A61B5/7239 ,  A61B5/726

    摘要： Methods and systems are discussed for determining venous oxygen saturation by calculating a ratio of ratios from respiration-induced baseline modulations. A calculated venous ratio of ratios may be compared with a look-up table value to estimate venous oxygen saturation. A calculated venous ratio of ratios is compared with an arterial ratio of ratios to determine whether baseline modulations are the result of a subject's respiration or movement. Such a determination is also made by deriving a venous ratio of ratios using a transform technique, such as a continuous wavelet transform. Derived venous and arterial saturation values are used to non-invasively determine a cardiac output of the subject.

    SYSTEMS AND METHODS FOR DETERMINING PHYSIOLOGICAL INFORMATION USING AUTOCORRELATION WITH GAPS
    6.
    发明申请
    SYSTEMS AND METHODS FOR DETERMINING PHYSIOLOGICAL INFORMATION USING AUTOCORRELATION WITH GAPS 审中-公开
    用GAPS自动识别生理信息的系统和方法

    公开(公告)号：US20130172686A1

    公开(公告)日：2013-07-04

    申请号：US13343421

    申请日：2012-01-04

    申请人： Paul S. Addison ,  James Dripps ,  James Ochs ,  James Watson

    发明人： Paul S. Addison ,  James Dripps ,  James Ochs ,  James Watson

    IPC分类号： A61B5/00

    CPC分类号： A61B5/7246 ,  A61B5/08 ,  A61B5/14551 ,  A61B5/7278

    摘要： A patient monitoring system may receive a physiological signal having gap portions in the received data. The gap portions may be identified and a plurality of morphology metric signals may be modified based on the identified gap portions. The morphology metric signals may be modified based on the identified gaps, and a combined autocorrelation sequence may be generated based on the modified morphology metric signals. The combined autocorrelation sequence may be used to determine physiological information.

    摘要翻译： 患者监视系统可以接收在所接收的数据中具有间隙部分的生理信号。 可以识别间隙部分，并且可以基于所识别的间隙部分来修改多个形态度量信号。 可以基于所识别的间隙修改形态度量信号，并且可以基于修改的形态度量信号来生成组合的自相关序列。 组合的自相关序列可用于确定生理信息。

    SYSTEMS AND METHODS FOR DETERMINING RESPIRATION INFORMATION FROM A PHOTOPLETHYSMOGRAPH
    8.
    发明申请
    SYSTEMS AND METHODS FOR DETERMINING RESPIRATION INFORMATION FROM A PHOTOPLETHYSMOGRAPH 有权
    用于从光电子能谱测定呼吸信息的系统和方法

    公开(公告)号：US20130080489A1

    公开(公告)日：2013-03-28

    申请号：US13243951

    申请日：2011-09-23

    申请人： James Ochs ,  Paul S. Addison ,  James Watson

    发明人： James Ochs ,  Paul S. Addison ,  James Watson

    IPC分类号： G06F17/15

    CPC分类号： A61B5/08 ,  A61B5/0205 ,  A61B5/02416 ,  A61B5/0816 ,  A61B5/7203

    摘要： A patient monitoring system may receive a photoplethysmograph (PPG) signal including samples of a pulse waveform. A plurality of morphology metric signals may be generated from the PPG signal. The system may generate an autocorrelation sequence for each of the morphology metric signals. An autocorrelation metric may be generated from each of the autocorrelation sequences and may represent the regularity or periodicity of the morphology metric signal. The autocorrelation sequences may be combined to generate a combined autocorrelation sequence, with the weighting of the autocorrelation sequences based on the autocorrelation metric. The combined autocorrelation sequence may be used to determine physiological information.

    摘要翻译： 患者监测系统可以接收包括脉搏波形样本的光电容积描记器（PPG）信号。 可以从PPG信号产生多个形态度量信号。 系统可以为每个形态度量信号产生自相关序列。 可以从每个自相关序列生成自相关度量，并且可以表示形态度量信号的规律性或周期性。 可以将自相关序列组合以产生组合自相关序列，其中基于自相关度量的自相关序列的加权。 组合的自相关序列可用于确定生理信息。

    SYSTEMS AND METHODS FOR DETERMINING RESPIRATION INFORMATION FROM A PHOTOPLETHYSMOGRAPH
    10.
    发明申请
    SYSTEMS AND METHODS FOR DETERMINING RESPIRATION INFORMATION FROM A PHOTOPLETHYSMOGRAPH 有权
    用于从光电子能谱测定呼吸信息的系统和方法

    公开(公告)号：US20130079606A1

    公开(公告)日：2013-03-28

    申请号：US13243853

    申请日：2011-09-23

    申请人： Scott McGonigle ,  Paul S. Addison ,  James Ochs ,  James Watson

    发明人： Scott McGonigle ,  Paul S. Addison ,  James Ochs ,  James Watson

    IPC分类号： A61B5/1455 ,  A61B5/08

    CPC分类号： A61B5/0816 ,  A61B5/14551 ,  A61B5/7232 ,  A61B5/7239

    摘要： A patient monitoring system may receive a photoplethysmograph (PPG) signal including samples of a pulse waveform. The PPG signal may demonstrate morphology changes based on respiration. The system may calculate morphology metrics from the PPG signal, the first derivative of the PPG signal, the second derivative of the PPG signal, or any combination thereof. The morphology metrics may demonstrate amplitude modulation, baseline modulation, and frequency modulation of the PPG signal that is related to respiration. Morphology metric signals generated from the morphology metrics may be used to determine respiration information such as respiration rate.

    摘要翻译： 患者监测系统可以接收包括脉搏波形样本的光电容积描记器（PPG）信号。 PPG信号可以显示基于呼吸的形态学变化。 该系统可以计算来自PPG信号，PPG信号的一阶导数，PPG信号的二阶导数或其任何组合的形态度量。 形态学指标可以显示与呼吸相关的PPG信号的幅度调制，基线调制和频率调制。 从形态学指标产生的形态学度量信号可用于确定呼吸信息，例如呼吸速率。