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公开(公告)号:US07497686B2
公开(公告)日:2009-03-03
申请号:US11171965
申请日:2005-06-30
IPC分类号: A61C5/00
CPC分类号: A61L27/3804 , A61K35/12 , A61L27/3604 , A61L27/3865 , A61L27/3895 , A61L2430/02 , C12N5/0606 , C12N5/0623 , C12N5/0663
摘要: The present invention is based on the discovery that when a tooth primordium is inserted into a mammalian jaw and tooth formation follows, new alveolar bone around the new tooth forms. The present invention is based on the idea of stimulating new tooth formation via the implantation of tooth primordia at selected places in the jaw (e.g. at four points in the molar regions) to result in the formation of bony protuberances which could facilitate denture retention. The teeth may then be removed from the jaw of the patient to leave the new alveolar bone.
摘要翻译: 本发明基于以下发现:当牙根原基插入到哺乳动物颌部并且牙齿形成时,新牙齿周围的新牙槽骨形成。 本发明基于通过在钳口中的选定位置(例如,在摩擦区域中的四个点)植入牙齿原基来刺激新牙齿形成的想法,以导致形成可以促进义齿保留的骨突起物。 然后可以从患者的颌骨上移除牙齿以离开新的牙槽骨。
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2.
公开(公告)号:US5739237A
公开(公告)日:1998-04-14
申请号:US682536
申请日:1996-07-29
IPC分类号: A61L27/00 , A61L27/34 , A61L33/00 , A61L33/06 , C07F9/54 , C08F20/02 , C08F20/34 , C08F20/60 , C08F30/02 , C07F9/06 , C07F9/22 , C07F9/28 , C08F20/58
CPC分类号: C07F9/5407 , A61L27/34 , A61L33/0082 , A61L33/0088 , A61L33/064
摘要: New materials having improved biocompatibility have novel zwitterionic groups at the surface. The zwitterion is characterized by having at least one monovalent substituent at the atom carrying the cationic charge which is an aryl group. Preferably the atom carries at least two, and preferably three such aryl, usually phenyl, groups. The cationic group is preferably a triphenylphosphonium. Treatment of surfaces to provide pendant zwitterionic groups of the specified type have reduced platelet activation, whilst they do not appear to reduce platelet adhesion. The invention has utility in the field of blood contacting device, especially devices for implantation, such as vascular grafts.
摘要翻译: PCT No.PCT / GB95 / 00161 Sec。 371日期:1996年7月29日 102(e)日期1996年7月29日PCT 1995年1月27日PCT PCT。 WO95 / 20407 PCT出版物 日期1995年8月3日具有改善的生物相容性的新材料在表面具有新的两性离子基团。 两性离子的特征在于在携带作为芳基的阳离子电荷的原子上具有至少一个一价取代基。 优选地,原子携带至少两个,优选三个这样的芳基,通常为苯基。 阳离子基团优选为三苯基鏻。 处理表面以提供指定类型的侧基两性离子基团具有降低的血小板活化,而它们似乎不降低血小板粘附。 本发明在血液接触装置领域具有实用性,尤其是用于植入的装置,例如血管移植物。
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