摘要:
Compounds of the formula ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, R.sup.7, X and Y have the signficance given in the description, are useful in the control or prevention of inflammatory, immunological, bronchopulmonary or cardiovascular disorders.
摘要:
Compounds of the formula ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, R.sup.7, X and Y have the signficance given in the description, are useful in the control or prevention of inflammatory, immunological, bronchopulmonary or cardiovascular disorders.
摘要:
Compounds of the formula ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, R.sup.7, X, m, n, p, and q are as set forth in the specification, as well as pharmaceutically acceptable salts of acidic compounds of formula I with bases and of basic compounds of formula I with acids, which are useful in the control or prevention of inflammatory, immunological, oncological, bronchopulmonary, dermatological or cardiovascular disorders or for the treatment of asthma, AIDS or diabetic complications or for the stimulation of hair growth are described.
摘要:
Vascular damaging agents composed of substituted 5(6)-substituted benzimidazole-2-carbamates are provided. These agents are useful in the preparation of medicaments for the treatment of diseases involving neovascularisation, particularly for the treatment of solid tumors, macular degeneration, diabetic retinopathy, rheumatoid arthritis, psoriasis, and atherosclerosis. Embodiments include a 5(6)-substituted benzimidazole-2-carbamate of formula I wherein A represents a multi-substituted alkyl group or aromatic ring.
摘要:
A wheel assembly for a small-scale machine includes a pair of opposing, individually-driven wheels, associated motors and possibly one or more gear assemblies. The motors receive separate drive signals from a control electronics subsystem of the wheel assembly. The motors can be connected to the wheels via the gear assemblies. Because the wheels are separately driven, driving the two wheel assemblies at similar or different speeds drives the wheel assembly over straight or curved paths. An orientation assembly allows the orientation of the wheels to the machine to be controllably altered. A height adjusting assembly allows the distance between the wheels and a point on the machine where the wheel assembly is attached to be adjusted. The rotational axis that the wheel assembly rotates about when re-oriented need not pass through either wheel of the wheel assembly. The wheels can be driven by control signals generated by on-board control electronics.