Substituted pyrroles
    3.
    发明授权
    Substituted pyrroles 失效
    取代吡咯

    公开(公告)号:US5292747A

    公开(公告)日:1994-03-08

    申请号:US949185

    申请日:1992-09-21

    摘要: Compounds of the formula ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, R.sup.7, X, m, n, p, and q are as set forth in the specification, as well as pharmaceutically acceptable salts of acidic compounds of formula I with bases and of basic compounds of formula I with acids, which are useful in the control or prevention of inflammatory, immunological, oncological, bronchopulmonary, dermatological or cardiovascular disorders or for the treatment of asthma, AIDS or diabetic complications or for the stimulation of hair growth are described.

    摘要翻译: 其中R 1,R 2,R 3,R 4,R 5,R 6,R 7,X,m,n,p和q如说明书中所述,以及其酸性化合物的药学上可接受的盐 具有碱和式I的碱式化合物的酸与酸反应,其可用于控制或预防炎症,免疫学,肿瘤学,支气管肺,皮肤病学或心血管疾病或用于治疗哮喘,AIDS或糖尿病并发症或用于 描述了毛发生长的刺激。

    Benzimidazole vascular damaging agents
    4.
    发明授权
    Benzimidazole vascular damaging agents 失效
    苯并咪唑血管损伤剂

    公开(公告)号:US07875727B2

    公开(公告)日:2011-01-25

    申请号:US11483639

    申请日:2006-07-11

    申请人: Peter D. Davis

    发明人: Peter D. Davis

    IPC分类号: C07D235/28 A61K31/4184

    摘要: Vascular damaging agents composed of substituted 5(6)-substituted benzimidazole-2-carbamates are provided. These agents are useful in the preparation of medicaments for the treatment of diseases involving neovascularisation, particularly for the treatment of solid tumors, macular degeneration, diabetic retinopathy, rheumatoid arthritis, psoriasis, and atherosclerosis. Embodiments include a 5(6)-substituted benzimidazole-2-carbamate of formula I wherein A represents a multi-substituted alkyl group or aromatic ring.

    摘要翻译: 提供由取代的5(6) - 取代的苯并咪唑-2-氨基甲酸酯组成的血管损伤剂。 这些试剂可用于制备用于治疗涉及新血管形成的疾病的药物,特别是用于治疗实体瘤,黄斑变性,糖尿病性视网膜病,类风湿性关节炎,牛皮癣和动脉粥样硬化。 实施方案包括式I的5(6) - 取代的苯并咪唑-2-氨基甲酸酯,其中A表示多取代的烷基或芳环。

    Modular dual wheel drive assembly, wheeled devices that include modular dual wheel drive assemblies and methods for moving and/or maneuvering wheeled devices using modular dual wheel drive assemblies
    5.
    发明授权
    Modular dual wheel drive assembly, wheeled devices that include modular dual wheel drive assemblies and methods for moving and/or maneuvering wheeled devices using modular dual wheel drive assemblies 有权
    模块化双轮驱动组件,包括模块化双轮驱动组件的轮式装置和使用模块化双轮驱动组件移动和/或操纵轮式装置的方法

    公开(公告)号:US07789175B2

    公开(公告)日:2010-09-07

    申请号:US11247652

    申请日:2005-10-11

    IPC分类号: B60K1/00

    摘要: A wheel assembly for a small-scale machine includes a pair of opposing, individually-driven wheels, associated motors and possibly one or more gear assemblies. The motors receive separate drive signals from a control electronics subsystem of the wheel assembly. The motors can be connected to the wheels via the gear assemblies. Because the wheels are separately driven, driving the two wheel assemblies at similar or different speeds drives the wheel assembly over straight or curved paths. An orientation assembly allows the orientation of the wheels to the machine to be controllably altered. A height adjusting assembly allows the distance between the wheels and a point on the machine where the wheel assembly is attached to be adjusted. The rotational axis that the wheel assembly rotates about when re-oriented need not pass through either wheel of the wheel assembly. The wheels can be driven by control signals generated by on-board control electronics.

    摘要翻译: 用于小型机器的车轮组件包括一对相对的单独驱动的车轮,相关联的电动机以及可能的一个或多个齿轮组件。 电机从车轮组件的控制电子系统子系统接收单独的驱动信号。 电机可以通过齿轮组件连接到车轮。 由于车轮是单独驱动的,以相似或不同的速度驱动两个车轮组件可以将车轮组件驱动在直线或弯曲的路径上。 定向组件允许可控地改变车轮对机器的定向。 高度调节组件允许车轮与车轮组件附接的机器上的点之间的距离被调节。 轮组件在重新定向时绕其旋转的旋转轴线不需要通过轮组件的任一轮。 车轮可以由车载控制电子产生的控制信号驱动。