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1.发明申请Role of PI3K P110 Delta Signaling in Retroviral Infection and Replication 审中-公开PI3K P110 Delta信号在逆转录病毒感染和复制中的作用公开(公告)号：US20130116267A1
公开(公告)日：2013-05-09
申请号：US13809713
申请日：2011-07-13
IPC分类号： A61K31/52 , A61K31/506 , A61K31/519
CPC分类号： A61K38/45 , A01K67/0276 , A01K2217/075 , A01K2227/105 , A01K2267/0337 , C12N9/1205 , C12N15/8509 , C12N2760/16111
摘要： The invention includes compositions and methods for regulating PI3K p110 delta as an anti-retroviral therapy. The invention includes a method of inhibiting p110 delta, a component of PI3K p110 delta signaling pathway, or any combination thereof in a cell as an anti-retroviral therapeutic approach for treating a retroviral infection, for example HTV. The invention includes a method of modulating PI3K p110 delta in a cell infected with a retrovirus by contacting the cell with an effective amount of a composition comprising an inhibitor of PI3K P110 delta.
摘要翻译： 本发明包括用于调节PI3Kp110δ作为抗逆转录病毒疗法的组合物和方法。 本发明包括在细胞中抑制p110δ，PI3Kp110δ信号通路的成分或其任何组合的方法，作为用于治疗逆转录病毒感染的抗逆转录病毒治疗方法，例如HTV。 本发明包括通过使细胞与有效量的包含PI3KP110δ的抑制剂的组合物接触来调节感染逆转录病毒的细胞中的PI3Kp110δ的方法。
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2.发明申请Compositions and Methods for Preventing or Treating Influenza Virus Infection 审中-公开用于预防或治疗流感病毒感染的组合物和方法公开(公告)号：US20120184519A1
公开(公告)日：2012-07-19
申请号：US13418045
申请日：2012-03-12
IPC分类号： A61K31/58 , A61K31/52 , A61K31/506 , C12N5/071 , A61K31/55 , A61P31/16 , A61P37/02 , A61P29/00 , A61K31/522 , A61K31/5377
CPC分类号： A61K38/45 , A01K67/0276 , A01K2217/075 , A01K2227/105 , A01K2267/0337 , C12N9/1205 , C12N15/8509 , C12N2760/16111
摘要： The invention includes compositions and methods for regulating PI3K p110 delta as an anti-retroviral therapy. The invention includes inhibiting p110 delta, a component of PI3K p110 delta signaling pathway, or any combination thereof in a cell as an anti-retroviral therapeutic approach for treating a retroviral infection, for example HIV. The invention includes a method of modulating PI3K p110 delta in a cell infected with a retrovirus by contacting the cell with an effective amount of a composition comprising an inhibitor of PI3K p110 delta.
摘要翻译： 本发明包括用于调节PI3Kp110δ作为抗逆转录病毒疗法的组合物和方法。 本发明包括在细胞中抑制p110δ，PI3Kp110δ信号通路的组分或其任何组合，作为用于治疗逆转录病毒感染的抗逆转录病毒治疗方法，例如HIV。 本发明包括通过使细胞与有效量的包含PI3Kp110δ的抑制剂的组合物接触来调节感染逆转录病毒的细胞中的PI3Kp110δ的方法。
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3.发明申请Role of PI3K p110 delta Signaling in Retroviral Infection and Replication 审中-公开PI3K p110三角信号在逆转录病毒感染和复制中的作用公开(公告)号：US20110135655A1
公开(公告)日：2011-06-09
申请号：US12835474
申请日：2010-07-13
CPC分类号： A61K38/45 , A01K67/0276 , A01K2217/075 , A01K2227/105 , A01K2267/0337 , C12N9/1205 , C12N15/8509 , C12N2760/16111
摘要： The invention includes compositions and methods for regulating PI3K p110 delta as an anti-retroviral therapy. The invention includes inhibiting p110 delta, a component of PI3K p110 delta signaling pathway, or any combination thereof in a cell as an anti-retroviral therapeutic approach for treating a retroviral infection, for example HIV. The invention includes a method of modulating PI3K p110 delta in a cell infected with a retrovirus by contacting the cell with an effective amount of a composition comprising an inhibitor of PI3K p110 delta.
摘要翻译： 本发明包括用于调节PI3Kp110δ作为抗逆转录病毒疗法的组合物和方法。 本发明包括在细胞中抑制p110δ，PI3Kp110δ信号通路的组分或其任何组合，作为用于治疗逆转录病毒感染的抗逆转录病毒治疗方法，例如HIV。 本发明包括通过使细胞与有效量的包含PI3Kp110δ的抑制剂的组合物接触来调节感染逆转录病毒的细胞中的PI3Kp110δ的方法。
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4.发明申请The Role of p110 delta Signaling in Morbidity and Lung Pathology Induced by Influenza Virus Infection 审中-公开p110三角洲信号在流感病毒感染发病和肺部病理学中的作用公开(公告)号：US20120039905A1
公开(公告)日：2012-02-16
申请号：US13144267
申请日：2010-01-12
IPC分类号： A61K39/395 , C07H21/00 , C07K2/00 , C12N5/071 , C07K16/40 , A61P31/16 , A61K48/00 , A61K31/7088 , C07H21/02 , C12N15/63
CPC分类号： A01K67/0276 , A01K2217/075 , A01K2227/105 , A01K2267/0337 , A61K38/45 , C12N9/1205 , C12N15/8509 , C12N2760/16111
摘要： The invention includes compositions and methods for regulating p110 delta as an anti-influenza virus therapy. The invention includes inhibiting p110 delta, a component of p110 delta signaling pathway, or any combination thereof in a cell as an anti-influenza viral therapeutic approach for treating influenza virus infection. The invention includes a method of modulating p110 delta in a cell by contacting the cell with an effective amount of a composition comprising an inhibitor of p110 delta.
摘要翻译： 本发明包括将p110δ调节为抗流感病毒治疗的组合物和方法。 本发明包括在细胞中抑制p110δ，p110δ信号通路的组分或其任何组合，作为用于治疗流感病毒感染的抗流感病毒治疗方法。 本发明包括通过使细胞与有效量的包含p110δ的抑制剂的组合物接触来调节细胞中p110δ的方法。
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