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公开(公告)号:US20050261332A1
公开(公告)日:2005-11-24
申请号:US11098315
申请日:2005-04-04
申请人: Peter Distefano , Andrew Napper , Rory Curtis , Jay Luly , Jean-Francois Pons , Russell Thomas , Manuel Navia , Thomas Coulter , Jeffrey Saunders , Bard Geesaman
发明人: Peter Distefano , Andrew Napper , Rory Curtis , Jay Luly , Jean-Francois Pons , Russell Thomas , Manuel Navia , Thomas Coulter , Jeffrey Saunders , Bard Geesaman
IPC分类号: A61K31/422 , A61K31/4245 , A61K31/454 , A61K31/4745 , C07C311/32 , C07D413/02 , C07D471/02 , C07D471/10 , C07D43/02
CPC分类号: C07D471/10 , C07C311/32 , C07D401/12
摘要: Compounds of formulas (I), (II), (III), and (IV) and methods of treating disorders by administering a compound of formula (I), (II), (III), or (IV) are described herein. Examples of disorders include neoplastic disorders, fat-cell related disorders, neurodegenerative disorders, and metabolic disorders.
摘要翻译: 本文描述式(I),(II),(III)和(IV)的化合物和通过施用式(I),(II),(III)或(IV)的化合物来治疗病症的方法。 病症的实例包括肿瘤性疾病,脂肪细胞相关疾病,神经变性疾病和代谢紊乱。
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公开(公告)号:US20050187237A1
公开(公告)日:2005-08-25
申请号:US10982997
申请日:2004-11-04
申请人: Peter Distefano , Andrew Napper , Rory Curtis , Jay Luly , Manuel Navia , Russell Thomas , Jean-Francois Pons , Jeffrey Saunders
发明人: Peter Distefano , Andrew Napper , Rory Curtis , Jay Luly , Manuel Navia , Russell Thomas , Jean-Francois Pons , Jeffrey Saunders
IPC分类号: A61K31/438 , A61K31/4747 , A61K31/5377 , C07D413/14 , C07D471/10
CPC分类号: C07D471/10 , C07D221/20 , C07D401/12
摘要: Compounds of formula (I) are described herein The compounds can be used, for example, to modulate growth hormone secretagogue receptor (GHS-R). In some instances, the compounds can be used to treat obesity.
摘要翻译: 式(I)化合物在本文中描述。该化合物可用于例如调节生长激素促分泌素受体(GHS-R)。 在一些情况下,化合物可用于治疗肥胖症。
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公开(公告)号:US07897765B2
公开(公告)日:2011-03-01
申请号:US12367585
申请日:2009-02-09
申请人: Peter Distefano , Andrew Napper , Rory Curtis , Jay Luly , Manuel A. Navia , Russell J. Thomas , Jean-Francois Pons , Jeffrey O. Saunders
发明人: Peter Distefano , Andrew Napper , Rory Curtis , Jay Luly , Manuel A. Navia , Russell J. Thomas , Jean-Francois Pons , Jeffrey O. Saunders
IPC分类号: C07D401/00
CPC分类号: C07D471/10 , C07D221/20 , C07D401/12
摘要: Compounds of formula (I) are described herein The compounds can be used, for example, to modulate growth hormone secretagogue receptor (GHS-R). In some instances, the compounds can be used to treat obesity.
摘要翻译: 式(I)化合物在本文中描述。该化合物可用于例如调节生长激素促分泌素受体(GHS-R)。 在一些情况下,化合物可用于治疗肥胖症。
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公开(公告)号:US07504506B2
公开(公告)日:2009-03-17
申请号:US10982997
申请日:2004-11-04
申请人: Peter Distefano , Andrew Napper , Rory Curtis , Jay Luly , Manuel A. Navia , Russell J. Thomas , Jean-Francois Pons , Jeffrey O. Saunders
发明人: Peter Distefano , Andrew Napper , Rory Curtis , Jay Luly , Manuel A. Navia , Russell J. Thomas , Jean-Francois Pons , Jeffrey O. Saunders
IPC分类号: C07D215/00 , C07D209/00 , C07D491/00
CPC分类号: C07D471/10 , C07D221/20 , C07D401/12
摘要: Compounds of formula (I) are described herein The compounds can be used, for example, to modulate growth hormone secretagogue receptor (GHS-R). In some instances, the compounds can be used to treat obesity.
摘要翻译: 式(I)化合物在本文中描述。该化合物可用于例如调节生长激素促分泌素受体(GHS-R)。 在一些情况下,化合物可用于治疗肥胖症。
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公开(公告)号:US20090264410A1
公开(公告)日:2009-10-22
申请号:US12367585
申请日:2009-02-09
申请人: Peter Distefano , Andrew Napper , Rory Curtis , Jay Luly , Manuel A. Navia , Russell J. Thomas , Jean-Francois Pons , Jeffrey O. Saunders
发明人: Peter Distefano , Andrew Napper , Rory Curtis , Jay Luly , Manuel A. Navia , Russell J. Thomas , Jean-Francois Pons , Jeffrey O. Saunders
IPC分类号: A61K31/55 , A61K31/4747
CPC分类号: C07D471/10 , C07D221/20 , C07D401/12
摘要: Compounds of formula (I) are described herein The compounds can be used, for example, to modulate growth hormone secretagogue receptor (GHS-R). In some instances, the compounds can be used to treat obesity.
摘要翻译: 式(I)化合物在本文中描述。该化合物可用于例如调节生长激素促分泌素受体(GHS-R)。 在一些情况下,化合物可用于治疗肥胖症。
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公开(公告)号:US20050209300A1
公开(公告)日:2005-09-22
申请号:US10940269
申请日:2004-09-13
申请人: Andrew Napper , Peter Distefano , Rory Curtis , Jeffrey Hixon , Thomas McDonagh , L. Huber , Jonathan Solomon , Russell Thomas , Jean-Francois Pons
发明人: Andrew Napper , Peter Distefano , Rory Curtis , Jeffrey Hixon , Thomas McDonagh , L. Huber , Jonathan Solomon , Russell Thomas , Jean-Francois Pons
IPC分类号: A61K31/35 , A61K31/38 , A61K31/40 , A61K31/403 , A61K31/445 , C07D20060101
CPC分类号: A61K31/445 , A61K31/35 , A61K31/38 , A61K31/40 , A61K31/403 , C07D209/88
摘要: Compound of formula (I) and methods of treating disorders by administering a compound of formula (I) are described herein. Examples of disorders include neoplastic disorders, fat-cell related disorders, neurodegenerative disorders, and metabolic disorders.
摘要翻译: 本文描述式(I)化合物和通过施用式(I)化合物治疗病症的方法。 病症的实例包括肿瘤性疾病,脂肪细胞相关疾病,神经变性疾病和代谢紊乱。
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公开(公告)号:US20060074124A1
公开(公告)日:2006-04-06
申请号:US11077664
申请日:2005-03-11
申请人: Andrew Napper , Peter Distefano , Rory Curtis , Jeffrey Hixon , Thomas McDonagh , L. Huber , Jonathan Solomon , Russell Thomas , Jean-Francois Pons
发明人: Andrew Napper , Peter Distefano , Rory Curtis , Jeffrey Hixon , Thomas McDonagh , L. Huber , Jonathan Solomon , Russell Thomas , Jean-Francois Pons
IPC分类号: A61K31/403 , C07D209/82
CPC分类号: A61K31/403 , A61K31/404 , A61K31/437 , A61K31/4439 , A61K31/497 , A61K31/5377 , C07D209/18 , C07D209/88 , C07D209/94 , C07D471/04
摘要: Compound of formula (I) and methods of treating disorders by administering a compound of formula (I) are described herein. Examples of disorders include neoplastic disorders, fat-cell related disorders, neurodegenerative disorders, and metabolic disorders.
摘要翻译: 本文描述式(I)化合物和通过施用式(I)化合物治疗病症的方法。 病症的实例包括肿瘤性疾病,脂肪细胞相关疾病,神经变性疾病和代谢紊乱。
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公开(公告)号:US20050256181A1
公开(公告)日:2005-11-17
申请号:US11047757
申请日:2005-01-31
申请人: Peter Distefano , Alan Watson , Rory Curtis , Bard Geesaman , L. Cannon , Manuel Navia
发明人: Peter Distefano , Alan Watson , Rory Curtis , Bard Geesaman , L. Cannon , Manuel Navia
IPC分类号: A61K31/403
CPC分类号: A61K31/403
摘要: Heterocyclic compounds of formula (I) and methods of treating or preventing an HIV-mediated disorder by administering a compound of formula (I) are described herein.
摘要翻译: 本文描述式(I)的杂环化合物和通过施用式(I)化合物来治疗或预防HIV介导的病症的方法。
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公开(公告)号:US20060019952A1
公开(公告)日:2006-01-26
申请号:US11048490
申请日:2005-01-31
申请人: Peter Distefano , Alan Watson , Rory Curtis , Bard Geesaman , L. Cannon , Manuel Navia
发明人: Peter Distefano , Alan Watson , Rory Curtis , Bard Geesaman , L. Cannon , Manuel Navia
IPC分类号: A61K31/5377 , A61K31/519 , A61K31/381 , A61K31/40
CPC分类号: A61K31/00 , A61K31/381 , A61K31/40 , A61K31/519 , A61K31/5377
摘要: Heterocyclic compounds of formula (I), (II), (III), and (IV) and methods of treating or preventing an HIV-mediated disorder by administering a compound of formula (I), (II), (III), or (IV) are described herein.
摘要翻译: 式(I),(II),(III)和(IV)的杂环化合物以及通过给予式(I),(II),(III)或 (IV)。
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公开(公告)号:US20050250794A1
公开(公告)日:2005-11-10
申请号:US11018018
申请日:2004-12-20
申请人: Andrew Napper , Peter Distefano , Rory Curtis , Jeffrey Hixon , Thomas McDonagh
发明人: Andrew Napper , Peter Distefano , Rory Curtis , Jeffrey Hixon , Thomas McDonagh
IPC分类号: A61K31/40 , A61K31/4245 , A61K31/433 , A61K31/4741 , A61K31/519
CPC分类号: A61K31/40 , A61K31/4245 , A61K31/433 , A61K31/4741 , A61K31/519
摘要: Heterocyclic compounds of formula (I), (II), (III), and (IV) and methods of treating disorders by administering a compound of formula (I) (II), (III), or (IV) are described herein. Examples of disorders include neoplastic disorders, fat-cell related disorders, neurodegenerative disorders, and metabolic disorders.
摘要翻译: 本文描述式(I),(II),(III)和(IV)的杂环化合物和通过施用式(I)(II),(III)或(IV)的化合物来治疗病症的方法。 病症的实例包括肿瘤性疾病,脂肪细胞相关疾病,神经变性疾病和代谢紊乱。
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