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公开(公告)号:US20060008881A1
公开(公告)日:2006-01-12
申请号:US10960652
申请日:2004-10-07
申请人: Peter Larsen , Stephen Fey , Allan Karlsen , Thomas Sparre , Jorn Nerup
发明人: Peter Larsen , Stephen Fey , Allan Karlsen , Thomas Sparre , Jorn Nerup
IPC分类号: C07K14/575 , C07H21/04 , A61K38/24
CPC分类号: C07K14/47 , A61K38/00 , G01N2800/042
摘要: Provided are mammalian secreted and non-secreted diabetes mediating proteins, including protective and deleterious diabetes-mediating proteins, as well as polynucleotides encoding same, drug screening methods for identifying a test compound capable of altering the expression of a diabetes-mediating protein, and methods of preventing or ameliorating diabetes by administering a compound capable of the expression of a diabetes-mediating protein.
摘要翻译: 提供哺乳动物分泌和非分泌的糖尿病介导蛋白质,包括保护性和有害的糖尿病介导蛋白质,以及编码它们的多核苷酸,用于鉴定能够改变糖尿病介导蛋白质的表达的测试化合物的药物筛选方法,以及方法 通过施用能够表达糖尿病介导蛋白质的化合物来预防或改善糖尿病。
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公开(公告)号:US07279274B2
公开(公告)日:2007-10-09
申请号:US10960652
申请日:2004-10-07
CPC分类号: C07K14/47 , A61K38/00 , G01N2800/042
摘要: Provided are mammalian secreted and non-secreted diabetes mediating proteins, including protective and deleterious diabetes-mediating proteins, as well as polynucleotides encoding same, drug screening methods for identifying a test compound capable of altering the expression of a diabetes-mediating protein, and methods of preventing or ameliorating diabetes by administering a compound capable of the expression of a diabetes-mediating protein.
摘要翻译: 提供哺乳动物分泌和非分泌的糖尿病介导蛋白质,包括保护性和有害的糖尿病介导蛋白质,以及编码它们的多核苷酸,用于鉴定能够改变糖尿病介导蛋白质的表达的测试化合物的药物筛选方法,以及方法 通过施用能够表达糖尿病介导蛋白质的化合物来预防或改善糖尿病。
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公开(公告)号:US20080145868A1
公开(公告)日:2008-06-19
申请号:US11869546
申请日:2007-10-09
IPC分类号: G01N33/53
CPC分类号: C07K14/47 , A61K38/00 , G01N2800/042
摘要: Provided are mammalian secreted and non-secreted diabetes mediating proteins, including protective and deleterious diabetes-mediating proteins, as well as polynucleotides encoding same, drug screening methods for identifying a test compound capable of altering the expression of a diabetes-mediating protein, and methods of preventing or ameliorating diabetes by administering a compound capable of the expression of a diabetes-mediating protein.
摘要翻译: 提供哺乳动物分泌和非分泌的糖尿病介导蛋白质,包括保护性和有害的糖尿病介导蛋白质,以及编码它们的多核苷酸,用于鉴定能够改变糖尿病介导蛋白质的表达的测试化合物的药物筛选方法,以及方法 通过施用能够表达糖尿病介导蛋白质的化合物来预防或改善糖尿病。
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