Mammalian diabetes-mediating proteins
    1.
    发明申请
    Mammalian diabetes-mediating proteins 失效
    哺乳动物糖尿病介导蛋白

    公开(公告)号:US20060008881A1

    公开(公告)日:2006-01-12

    申请号:US10960652

    申请日:2004-10-07

    摘要: Provided are mammalian secreted and non-secreted diabetes mediating proteins, including protective and deleterious diabetes-mediating proteins, as well as polynucleotides encoding same, drug screening methods for identifying a test compound capable of altering the expression of a diabetes-mediating protein, and methods of preventing or ameliorating diabetes by administering a compound capable of the expression of a diabetes-mediating protein.

    摘要翻译: 提供哺乳动物分泌和非分泌的糖尿病介导蛋白质,包括保护性和有害的糖尿病介导蛋白质,以及编码它们的多核苷酸,用于鉴定能够改变糖尿病介导蛋白质的表达的测试化合物的药物筛选方法,以及方法 通过施用能够表达糖尿病介导蛋白质的化合物来预防或改善糖尿病。

    Proteins in diabetes proteome anlysis
    2.
    发明申请
    Proteins in diabetes proteome anlysis 审中-公开
    蛋白质组蛋白质分解蛋白质

    公开(公告)号:US20050118151A1

    公开(公告)日:2005-06-02

    申请号:US10982218

    申请日:2004-11-05

    摘要: Provided are mammalian secreted and non-secreted diabetes mediating proteins, including protective and deleterious diabetes-mediating proteins, as well as polynucleotides encoding same, drug screening methods for identifying a test compound capable of altering the expression of a diabetes-mediating protein, and methods of preventing or ameliorating diabetes by administering a compound capable of altering the expression of a diabetes-mediating protein.

    摘要翻译: 提供哺乳动物分泌和非分泌的糖尿病介导蛋白质,包括保护性和有害的糖尿病介导蛋白质,以及编码它们的多核苷酸,用于鉴定能够改变糖尿病介导蛋白质的表达的测试化合物的药物筛选方法,以及方法 通过施用能够改变糖尿病介导蛋白的表达的化合物来预防或改善糖尿病。

    Human diabetes-mediating proteins
    4.
    发明申请
    Human diabetes-mediating proteins 失效
    人类糖尿病介导蛋白

    公开(公告)号:US20060073134A1

    公开(公告)日:2006-04-06

    申请号:US10508255

    申请日:2003-03-20

    摘要: Provided are human secreted and non-secreted diabetes mediating proteins, including protective and deleterious diabetes-mediating proteins, as well as polynucleotides encoding same, drug screening methods for identifying a test compound capable of altering the expression of a diabetes-mediating proteins, and methods of preventing or ameliorating diabetes by administering a compound capable of altering the expression of a diabetes-mediating protein.

    摘要翻译: 提供的是人分泌和非分泌的糖尿病介导蛋白质,包括保护性和有害的糖尿病介导蛋白质,以及编码它们的多核苷酸,用于鉴定能够改变糖尿病介导蛋白质的表达的测试化合物的药物筛选方法和方法 通过施用能够改变糖尿病介导蛋白的表达的化合物来预防或改善糖尿病。

    Method of separating biocomponents contained in a liquid, a separating system and a separating unit
    6.
    发明申请
    Method of separating biocomponents contained in a liquid, a separating system and a separating unit 审中-公开
    分离液体,分离系统和分离单元中包含的生物组分的方法

    公开(公告)号:US20050150769A1

    公开(公告)日:2005-07-14

    申请号:US11004974

    申请日:2004-12-07

    摘要: The invention relates to a method of separating at least two biocomponents contained in a liquid including having different pI values. The method comprising the steps of: i. providing a first separating path with at least one separating layer comprising one or more pH active components with pH active groups, ii. applying the liquid with the biocomponents to the separating coating, iii: applying a voltage over the separating path, iv. allowing at least some of the biocomponents to travel towards one of the electrodes to one or more collection stations, v. collecting the once separated biocomponents from at least one collection station. The invention also relates to a separating system for use in the method. The separation system comprises a set of separating paths, the separating system comprising 2 or more separating paths that differ from each other with respect to the pH value of the separating coating.

    摘要翻译: 本发明涉及一种分离包含在液体中的至少两种生物组分的方法,包括具有不同pI值。 该方法包括以下步骤:i。 提供具有至少一个包含一个或多个具有pH活性基团的pH活性组分的分离层的第一分离路径,ii。 将液体与生物组分一起施加到分离涂层,iii:在分离路径上施加电压,iv。 允许至少一些生物组分行进到一个或多个收集站的电极之一,v。从至少一个收集站收集一次分离的生物组分。 本发明还涉及一种用于该方法的分离系统。 分离系统包括一组分离路径,分离系统包含相对于分离涂层的pH值彼此不同的2个或更多个分离路径。