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公开(公告)号：US09752170B2
公开(公告)日：2017-09-05
申请号：US14655034
申请日：2013-04-17
发明人： Saravanakumar Iyappan , Samir Kumar Roy , Saju Varghese , Aparna Devi Addala , Venkata Narayanan Karthikeyan , Kanumuru Rahul Raju , Banibrata Pandey
CPC分类号： C12P19/24 , C12N9/90 , C12P19/02 , C12Y501/03 , C12Y503/01014
摘要： The present invention is directed towards genetic modification of native gene encoding for D-tagatose 3-epimerase and rhamnose isomerase to substantially increase the expression level of these enzymes and use of the enzymes in a process to produce rare monosaccharides such as psicose and allose. Also disclosed in the present invention is expression constructs comprising the modified genes and a host cells to express the same.
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公开(公告)号：US09885030B2
公开(公告)日：2018-02-06
申请号：US15605816
申请日：2017-05-25
发明人： Samir Kumar Roy , Saravanakumar Iyappan , Saju Varghese , Aparna Devi Addala , Milky Agarwal , Kanumuru Rahul Raju , Banibrata Pandey
CPC分类号： C12N9/90 , C12P19/12 , C12P19/24 , C12Y504/99011
摘要： The present invention is directed towards genetic modification of native gene encoding for sucrose isomerase and isomaltulose synthase to substantially increase the expression level of these enzymes and use of said enzymes in a process to produce rare disaccharides such as isomaltulose and trehalulose. Also disclosed in the present invention is expression constructs comprising the modified genes and a host cells to express the same.
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公开(公告)号：US20170267989A1
公开(公告)日：2017-09-21
申请号：US15605816
申请日：2017-05-25
发明人： Samir Kumar Roy , Saravanakumar Iyappan , Saju Varghese , Aparna Devi Addala , Milky Agarwal , Kanumuru Rahul Raju , Banibrata Pandey
CPC分类号： C12N9/90 , C12P19/12 , C12P19/24 , C12Y504/99011
摘要： The present invention is directed towards genetic modification of native gene encoding for sucrose isomerase and isomaltulose synthase to substantially increase the expression level of these enzymes and use of said enzymes in a process to produce rare disaccharides such as isomaltulose and trehalulose. Also disclosed in the present invention is expression constructs comprising the modified genes and a host cells to express the same.
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公开(公告)号：US09695411B2
公开(公告)日：2017-07-04
申请号：US14655035
申请日：2013-04-17
发明人： Samir Kumar Roy , Saravanakumar Iyappan , Saju Varghese , Aparna Devi Addala , Milky Agarwal , Kanumuru Rahul Raju , Banibrata Pandey
CPC分类号： C12N9/90 , C12P19/12 , C12P19/24 , C12Y504/99011
摘要： The present invention is directed towards genetic modification of native gene encoding for sucrose isomerase and isomaltulose synthase to substantially increase the expression level of these enzymes and use of said enzymes in a process to produce rare disaccharides such as isomaltulose and trehalulose. Also disclosed in the present invention is expression constructs comprising the modified genes and a host cells to express the same.
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