专利检索 ap:("Pfizer Limited") AND inv:"Karl Richard Gibson" 第 1 页

1.

发明授权
Pyrrolo[3,2-c]pyridine tropomyosin-related kinase inhibitors 有权
标题翻译：吡咯并[3,2-c]吡啶原肌球蛋白相关激酶抑制剂

公开(公告)号：US09163021B2

公开(公告)日：2015-10-20

申请号：US14430286

申请日：2013-09-26

申请人： Pfizer Limited

发明人： Mark David Andrews , Sharanjeet Kaur Bagal , David Graham Brown , Karl Richard Gibson , Wolfgang Klute , Inaki Morao , Kiyoyuki Omoto , Thomas Ryckmans , Yogesh Sabnis , Sarah Elizabeth Skerratt , Paul Anthony Stupple

IPC分类号： C07D401/02 , C07D401/10 , A61K31/437 , A61K31/4353 , C07D471/04

CPC分类号： C07D471/04

摘要： The present invention relates to compounds of Formula (I) and their pharmaceutically acceptable salts, wherein the substituents are as described herein, and their use in medicine, in particular as Trk antagonists.

摘要翻译： 本发明涉及式（I）化合物及其药学上可接受的盐，其中取代基如本文所述，及其在药物中的用途，特别是作为Trk拮抗剂。

2.

发明申请
PYRROLO[2,3-d]PYRIMIDINE TROPOMYSIN-RELATED KINASE INHIBITORS 审中-公开
标题翻译：吡咯并[2,3-d]吡咯烷TROPOMYSIN相关激酶抑制剂

公开(公告)号：US20140364415A1

公开(公告)日：2014-12-11

申请号：US14468614

申请日：2014-08-26

申请人： PFIZER LIMITED

发明人： Mark David Andrews , Sharanjeet Kaur Bagal , Karl Richard Gibson , Kiyoyuki Omoto , Thomas Ryckmans , Sarah Elizabeth Skerratt , Paul Anthony Stupple

IPC分类号： C07D487/04 , C07D513/04

CPC分类号： C07D487/04 , A61K31/519 , C07D513/04

摘要： The present invention relates to compounds of Formula (I) and their pharmaceutically acceptable salts, wherein the substituents are as described herein, and their use in medicine, in particular as Trk antagonists.

摘要翻译： 本发明涉及式（I）化合物及其药学上可接受的盐，其中取代基如本文所述，及其在药物中的用途，特别是作为Trk拮抗剂。

3.

发明申请
Pyrrolo[3,2-C]Pyridine Tropomyosin-Related Kinase Inhibitors 审中-公开
标题翻译：吡咯并[3,2-C]吡啶基原肌球蛋白相关激酶抑制剂

公开(公告)号：US20150246912A1

公开(公告)日：2015-09-03

申请号：US14430286

申请日：2013-09-26

申请人： Pfizer Limited

发明人： Mark David Andrews , Sharanjeet Kaur Bagal , David Graham Brown , Karl Richard Gibson , Wolfgang Klute , Inaki Morao , Kiyoyuki Omoto , Thomas Ryckmans , Yogesh Sabnis , Sarah Elizabeth Skerratt , Paul Anthony Stupple

IPC分类号： C07D471/04

CPC分类号： C07D471/04

摘要： The present invention relates to compounds of Formula (I) and their pharmaceutically acceptable salts, wherein the substituents are as described herein, and their use in medicine, in particular as Trk antagonists.

摘要翻译： 本发明涉及式（I）化合物及其药学上可接受的盐，其中取代基如本文所述，及其在药物中的用途，特别是作为Trk拮抗剂。

4.

发明申请
Pyrrolo[2,3-D]Pyrimidine Tropomyosin-Related Kinase Inhibitors 审中-公开
标题翻译：吡咯并[2,3-D]嘧啶原肌球蛋白相关激酶抑制剂

公开(公告)号：US20150218172A1

公开(公告)日：2015-08-06

申请号：US14428997

申请日：2013-09-26

申请人： PFIZER LIMITED

发明人： Mark David Andrews , Sharanjeet Kaur Bagal , David Graham Brown , Karl Richard Gibson , Kiyoyuki Omoto , Thomas Ryckmans , Yogesh Sabnis , Sarah Elizabeth Skerratt , Paul Anthony Stupple

IPC分类号： C07D487/04 , A61K31/519

CPC分类号： C07D487/04 , A61K31/519

摘要： The present invention relates to compounds of Formula (I) and their pharmaceutically acceptable salts, wherein the substituents are as described herein, and their use in medicine, in particular as Trk antagonists.

摘要翻译： 本发明涉及式（I）化合物及其药学上可接受的盐，其中取代基如本文所述，及其在药物中的用途，特别是作为Trk拮抗剂。