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公开(公告)号:US20130123230A1
公开(公告)日:2013-05-16
申请号:US13670852
申请日:2012-11-07
申请人: Philip A. Carpino , Edward L. Conn , Robert L. Dow , Matthew S. Dowling , David Hepworth , Daniel Wei-Shung Kung , Suvi Orr , Benjamin N. Rocke , Roger B. Ruggeri , Matthew F. Sammons , Joseph S. Warmus , Yan Zhang
发明人: Philip A. Carpino , Edward L. Conn , Robert L. Dow , Matthew S. Dowling , David Hepworth , Daniel Wei-Shung Kung , Suvi Orr , Benjamin N. Rocke , Roger B. Ruggeri , Matthew F. Sammons , Joseph S. Warmus , Yan Zhang
IPC分类号: C07D239/56 , C07D401/04 , C07D405/10 , C07D403/10 , C07D487/04 , C07D409/10 , C07D417/10 , C07D401/06 , C07D403/06 , C07D413/06 , A61K31/5377 , C07D405/04 , C07D403/04 , C07D409/04 , C07D401/10 , C07D403/12 , A61K31/352 , A61K45/06 , A61K31/513
CPC分类号: C07D239/56 , A61K31/352 , A61K31/37 , A61K31/513 , A61K31/5377 , A61K45/06 , C07D401/04 , C07D401/06 , C07D401/10 , C07D403/04 , C07D403/06 , C07D403/10 , C07D403/12 , C07D405/04 , C07D405/06 , C07D405/10 , C07D409/04 , C07D409/10 , C07D413/06 , C07D417/04 , C07D417/10 , C07D471/04 , C07D487/04 , A61K2300/00
摘要: Myeloperoxidase inhibitors, pharmaceutical compositions containing such inhibitors and the use of such inhibitors to treat, for example, cardiovascular conditions.
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公开(公告)号:US08288405B2
公开(公告)日:2012-10-16
申请号:US12941133
申请日:2010-11-08
IPC分类号: A61K31/438 , C07D401/14 , C07D401/04
CPC分类号: C07D471/10 , C07D519/00
摘要: The invention provides a compound of Formula (I) or a pharmaceutically acceptable salt of the compound, wherein R1, R2, R3 and R4 are as described herein; pharmaceutical compositions thereof; and the use thereof in treating diseases, conditions or disorders modulated by the inhibition of an acetyl-CoA carboxylase enzyme(s) in an animal.
摘要翻译: 本发明提供式(I)化合物或其药学上可接受的盐,其中R 1,R 2,R 3和R 4如本文所述; 其药物组合物; 以及其用于治疗通过抑制动物体内的乙酰辅酶A羧化酶调节的疾病,病症或病症的用途。
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3.
公开(公告)号:US20120225900A1
公开(公告)日:2012-09-06
申请号:US13508744
申请日:2010-10-28
IPC分类号: A61K31/438 , A61P3/04 , A61P3/06 , C07D471/10 , A61P3/10
CPC分类号: C07D471/10 , A61K31/416 , A61K45/06 , A61K2300/00
摘要: The invention provides a compound of Formula (I) or a pharmaceutically acceptable salt of said compound, wherein R1, R2, R3 and R4 are as described herein; pharmaceutical compositions thereof; and the use thereof in treating diseases, conditions or disorders modulated by the inhibition of an acetyl-CoA carboxylase enzyme(s) in an animal.
摘要翻译: 本发明提供式(I)化合物或所述化合物的药学上可接受的盐,其中R 1,R 2,R 3和R 4如本文所述; 其药物组合物; 以及其用于治疗通过抑制动物体内的乙酰辅酶A羧化酶调节的疾病,病症或病症的用途。
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