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公开(公告)号：US07220277B2
公开(公告)日：2007-05-22
申请号：US10393448
申请日：2003-03-20
IPC分类号： A61F2/24
CPC分类号： A61F2/2448 , A61F2250/0018
摘要： A prosthesis for annuloplasty comprising a laminar or tubular element having a plurality of apertures along at least one portion. Preferably, the shape, dimensions, and arrangements of the apertures in this prosthesis are chosen in such a way as to give the prosthesis a differentiated flexibility in dependence on the location and direction of application of an external stress.
摘要翻译： 用于瓣膜成形术的假体包括沿着至少一个部分具有多个孔的层状或管状元件。 优选地，这种假体中的孔的形状，尺寸和布置以这样的方式选择，以便根据施加外部应力的位置和方向给予假体差异的灵活性。
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公开(公告)号：US20070191940A1
公开(公告)日：2007-08-16
申请号：US11737474
申请日：2007-04-19
IPC分类号： A61F2/24
CPC分类号： A61F2/2448 , A61F2250/0018
摘要： A prosthesis for annuloplasty comprising a laminar or tubular element having a plurality of apertures along at least one portion. Preferably, the shape, dimensions, and arrangements of the apertures in this prosthesis are chosen in such a way as to give the prosthesis a differentiated flexibility in dependence on the location and direction of application of an external stress.
摘要翻译： 用于瓣膜成形术的假体包括沿着至少一个部分具有多个孔的层状或管状元件。 优选地，这种假体中的孔的形状，尺寸和布置以这样的方式选择，以便根据施加外部应力的位置和方向给予假体差异的灵活性。
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公开(公告)号：US08539662B2
公开(公告)日：2013-09-24
申请号：US12139686
申请日：2008-06-16
CPC分类号： A61F2/2418 , A61F2/2436 , A61F2/2469 , A61F2/848 , A61F2210/0014 , A61F2220/0008 , A61F2220/0075 , A61F2230/0054 , A61F2250/001 , Y10T29/49833
摘要： A cardiac-valve prosthesis which can be used, for example, as a valve for percutaneous implantation. The prosthesis includes an armature for anchorage of the valve prosthesis in the implantation site. The armature defines a lumen for passage of the blood flow and supports a set of prosthetic valve leaflets, which, under the action of the blood flow, are able to move into a radially divaricated condition to enable the flow of the blood through the lumen in a first direction and a radially contracted condition, in which the valve leaflets co-operate with one another and block the flow of the blood through the prosthesis in the opposite direction. The armature includes, in one embodiment, two annular elements connected by anchor members having the capacity of projecting radially with respect to the prosthesis, and support members for the set of leaflets, the support members being carried by at least one of the annular elements so as to leave substantially disengaged the aforesaid lumen for passage of the blood.
摘要翻译： 可用于例如用于经皮植入的瓣膜的心脏瓣膜假体。 假体包括用于在植入部位中锚定瓣膜假体的衔铁。 电枢限定一个用于血流通过的腔，并且支撑一组假性瓣叶，其在血液流动的作用下能够移动到径向分离的状态，以使血液能够通过内腔 第一方向和径向收缩状态，其中瓣叶彼此协作并阻止血液通过假体沿相反方向流动。 在一个实施例中，电枢包括通过相对于假体径向突出的能力的锚固构件连接的两个环形元件，以及用于该组叶片的支撑构件，支撑构件由至少一个环形元件承载 以使上述内腔基本脱离血液通过。
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公开(公告)号：US08109996B2
公开(公告)日：2012-02-07
申请号：US11066346
申请日：2005-02-25
IPC分类号： A61F2/24
CPC分类号： A61F2/2412 , A61F2/2418 , A61F2/2427 , A61F2250/0039
摘要： A cardiac-valve prosthesis is adapted for percutaneous implantation. The prosthesis includes an armature adapted for deployment in a radially expanded implantation position, the armature including a support portion and an anchor portion, which are substantially axially coextensive with respect to one another. A set of leaflets is coupled to the support portion. The leaflets can be deployed with the armature in the implantation position. The leaflets define, in the implantation position, a flow duct that is selectably obstructable. The anchor portion can be deployed to enable anchorage of the cardiac-valve prosthesis at an implantation site.
摘要翻译： 心脏瓣膜假体适用于经皮植入。 假体包括适于展开在径向扩张的植入位置的电枢，所述电枢包括支撑部分和锚定部分，所述支撑部分和锚定部分彼此基本轴向共延伸。 一组传单联接到支撑部分。 传单可以在植入位置上与衔铁一起展开。 在植入位置中，传单限定了可选择地阻塞的流动管道。 锚固部分可以被部署以使得能够在植入部位处锚定心脏瓣膜假体。
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公开(公告)号：US08540768B2
公开(公告)日：2013-09-24
申请号：US13341336
申请日：2011-12-30
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/2436 , A61F2/2469 , A61F2/848 , A61F2210/0014 , A61F2220/0008 , A61F2220/0075 , A61F2230/0054 , A61F2250/001 , Y10T29/49833
摘要： A cardiac valve prosthesis includes a frame and a set of prosthetic valve leaflets supported by the frame. The frame defines a principal axis of the cardiac valve prosthesis and includes first and second annular elements expandable from a radially contracted state to a radially expanded state, a plurality of valve supports supporting the leaflets, and a plurality of connecting members. The valve supports are angularly spaced from one another about the principal axis of the cardiac valve prosthesis, and the connecting members extend between and connect the first and second annular elements. When the annular elements are in the radially expanded state each of the connecting members arches radially outward with respect to the annular elements and is configured to project into one of the Valsalva sinuses when implanted. The connecting members are angularly spaced from the valve supports about the principal axis.
摘要翻译： 心脏瓣膜假体包括框架和由框架支撑的一组假体瓣膜小叶。 所述框架限定所述心脏瓣膜假体的主轴线并且包括从径向收缩状态向径向展开状态可扩张的第一和第二环形元件，支撑所述传单的多个瓣膜支撑件以及多个连接构件。 阀支撑件围绕心脏瓣膜假体的主轴线彼此成角度地间隔开，并且连接构件在第一和第二环形元件之间延伸并连接。 当环形元件处于径向膨胀状态时，每个连接构件相对于环形元件径向向外弯曲并且被配置为在植入时突入Valsalva鼻窦中的一个。 连接构件与阀支架围绕主轴线成角度地间隔开。
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公开(公告)号：US08535373B2
公开(公告)日：2013-09-17
申请号：US12139683
申请日：2008-06-16
IPC分类号： A61F2/24
CPC分类号： A61F2/2412 , A61F2/2418 , A61F2/2427 , A61F2250/0039
摘要： A cardiac-valve prosthesis is adapted for percutaneous implantation. The prosthesis includes an armature adapted for deployment in a radially expanded implantation position, the armature including a support portion and an anchor portion, which are substantially axially coextensive with respect to one another. A set of leaflets is coupled to the support portion. The leaflets can be deployed with the armature in the implantation position. The leaflets define, in the implantation position, a flow duct that is selectably obstructable. The anchor portion can be deployed to enable anchorage of the cardiac-valve prosthesis at an implantation site.
摘要翻译： 心脏瓣膜假体适用于经皮植入。 假体包括适于展开在径向扩张的植入位置的电枢，所述电枢包括支撑部分和锚定部分，所述支撑部分和锚定部分彼此基本轴向共延伸。 一组传单联接到支撑部分。 传单可以在植入位置上与衔铁一起展开。 在植入位置中，传单限定了可选择地阻塞的流动管道。 锚固部分可以被部署以使得能够在植入部位处锚定心脏瓣膜假体。
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公开(公告)号：US20120172982A1
公开(公告)日：2012-07-05
申请号：US13341336
申请日：2011-12-30
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/2436 , A61F2/2469 , A61F2/848 , A61F2210/0014 , A61F2220/0008 , A61F2220/0075 , A61F2230/0054 , A61F2250/001 , Y10T29/49833
摘要： A cardiac valve prosthesis includes a frame and a set of prosthetic valve leaflets supported by the frame. The frame defines a principal axis of the cardiac valve prosthesis and includes first and second annular elements expandable from a radially contracted state to a radially expanded state, a plurality of valve supports supporting the leaflets, and a plurality of connecting members. The valve supports are angularly spaced from one another about the principal axis of the cardiac valve prosthesis, and the connecting members extend between and connect the first and second annular elements. When the annular elements are in the radially expanded state each of the connecting members arches radially outward with respect to the annular elements and is configured to project into one of the Valsalva sinuses when implanted. The connecting members are angularly spaced from the valve supports about the principal axis.
摘要翻译： 心脏瓣膜假体包括框架和由框架支撑的一组假体瓣膜小叶。 所述框架限定所述心脏瓣膜假体的主轴线并且包括从径向收缩状态向径向展开状态可扩张的第一和第二环形元件，支撑所述传单的多个瓣膜支撑件以及多个连接构件。 阀支撑件围绕心脏瓣膜假体的主轴线彼此成角度地间隔开，并且连接构件在第一和第二环形元件之间延伸并连接。 当环形元件处于径向膨胀状态时，每个连接构件相对于环形元件径向向外弯曲并且被配置为在植入时突入Valsalva鼻窦中的一个。 连接构件与阀支架围绕主轴线成角度地间隔开。
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公开(公告)号：US07857845B2
公开(公告)日：2010-12-28
申请号：US11352021
申请日：2006-02-10
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/2436 , A61F2/2469 , A61F2/848 , A61F2210/0014 , A61F2220/0008 , A61F2220/0075 , A61F2230/0054 , A61F2250/001 , Y10T29/49833
摘要： A cardiac-valve prosthesis which can be used, for example, as a valve for percutaneous implantation. The prosthesis includes an armature for anchorage of the valve prosthesis in the implantation site. The armature defines a lumen for passage of the blood flow and supports a set of prosthetic valve leaflets, which, under the action of the blood flow, are able to move into a radially divaricated condition to enable the flow of the blood through the lumen in a first direction and a radially contracted condition, in which the valve leaflets co-operate with one another and block the flow of the blood through the prosthesis in the opposite direction. The armature includes, in one embodiment, two annular elements connected by anchor members having the capacity of projecting radially with respect to the prosthesis, and support members for the set of leaflets, the support members being carried by at least one of the annular elements so as to leave substantially disengaged the aforesaid lumen for passage of the blood.
摘要翻译： 可用于例如用于经皮植入的瓣膜的心脏瓣膜假体。 假体包括用于在植入部位中锚定瓣膜假体的衔铁。 电枢限定一个用于血流通过的腔，并且支撑一组假性瓣叶，其在血液流动的作用下能够移动到径向分离的状态，以使血液能够通过内腔 第一方向和径向收缩状态，其中瓣叶彼此协作并阻止血液通过假体沿相反方向流动。 在一个实施例中，电枢包括通过相对于假体径向突出的能力的锚固构件连接的两个环形元件，以及用于该组叶片的支撑构件，支撑构件由至少一个环形元件承载 以使上述内腔基本脱离血液通过。
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公开(公告)号：US20050197695A1
公开(公告)日：2005-09-08
申请号：US11066346
申请日：2005-02-25
IPC分类号： A61F2/24
CPC分类号： A61F2/2412 , A61F2/2418 , A61F2/2427 , A61F2250/0039
摘要： A cardiac-valve prosthesis is adapted for percutaneous implantation. The prosthesis includes an armature adapted for deployment in a radially expanded implantation position, the armature including a support portion and an anchor portion, which are substantially axially coextensive with respect to one another. A set of leaflets is coupled to the support portion. The leaflets can be deployed with the armature in the implantation position. The leaflets define, in the implantation position, a flow duct that is selectably obstructable. The anchor portion can be deployed to enable anchorage of the cardiac-valve prosthesis at an implantation site.
摘要翻译： 心脏瓣膜假体适用于经皮植入。 假体包括适于展开在径向扩张的植入位置的电枢，所述电枢包括支撑部分和锚定部分，所述支撑部分和锚定部分彼此基本轴向共延伸。 一组传单联接到支撑部分。 传单可以在植入位置上与衔铁一起展开。 在植入位置中，传单限定了可选择地阻塞的流动管道。 锚固部分可以被部署以使得能够在植入部位处锚定心脏瓣膜假体。
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公开(公告)号：US20080255662A1
公开(公告)日：2008-10-16
申请号：US12139683
申请日：2008-06-16
IPC分类号： A61F2/24
CPC分类号： A61F2/2412 , A61F2/2418 , A61F2/2427 , A61F2250/0039
摘要： A cardiac-valve prosthesis is adapted for percutaneous implantation. The prosthesis includes an armature adapted for deployment in a radially expanded implantation position, the armature including a support portion and an anchor portion, which are substantially axially coextensive with respect to one another. A set of leaflets is coupled to the support portion. The leaflets can be deployed with the armature in the implantation position. The leaflets define, in the implantation position, a flow duct that is selectably obstructable. The anchor portion can be deployed to enable anchorage of the cardiac-valve prosthesis at an implantation site.
摘要翻译： 心脏瓣膜假体适用于经皮植入。 假体包括适于展开在径向扩张的植入位置的电枢，所述电枢包括支撑部分和锚定部分，所述支撑部分和锚定部分彼此基本轴向共延伸。 一组传单联接到支撑部分。 传单可以在植入位置上与衔铁一起展开。 在植入位置中，传单限定了可选择地阻塞的流动管道。 锚固部分可以被部署以使得能够在植入部位处锚定心脏瓣膜假体。
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