METHOD AND APPARATUS FOR FABRICATING NANOPARTICLES
    1.
    发明申请
    METHOD AND APPARATUS FOR FABRICATING NANOPARTICLES 审中-公开
    制备纳米颗粒的方法和装置

    公开(公告)号:US20100025873A1

    公开(公告)日:2010-02-04

    申请号:US12260975

    申请日:2008-10-29

    IPC分类号: B29B9/12

    摘要: An apparatus and method for forming nanoparticles employs an inkjet dispenser and a nanoparticle formation device. The inkjet dispenser includes at least one orifice. A liquid solution with a substance to be transformed into nanoscale is received in the inkjet dispenser, and is dispensed from the at least one orifice to generate a plurality of microdroplets. The nanoparticle formation device is disposed to receive the microdroplets dispensed by the inkjet dispenser and form the nanoparticles therein.

    摘要翻译: 用于形成纳米颗粒的装置和方法采用喷墨分配器和纳米颗粒形成装置。 喷墨分配器包括至少一个孔口。 将具有待转化成纳米尺度的物质的液体溶液接收在喷墨分配器中,并从至少一个孔口分配以产生多个微滴。 纳米颗粒形成装置设置成接收由喷墨分配器分配的微滴并在其中形成纳米颗粒。

    Method and apparatus for fabricating nanoparticles
    2.
    发明申请
    Method and apparatus for fabricating nanoparticles 审中-公开
    制造纳米颗粒的方法和装置

    公开(公告)号:US20070059370A1

    公开(公告)日:2007-03-15

    申请号:US11229129

    申请日:2005-09-15

    IPC分类号: A61K9/14 B29B9/00

    摘要: An apparatus and method for forming nanoparticles employs an inkjet dispenser and a nanoparticle formation device. The inkjet dispenser includes at least one orifice. A liquid solution with a substance to be transformed into nanoscale is received in the inkjet dispenser, and is dispensed from the at least one orifice to generate a plurality of microdroplets. The nanoparticle formation device is disposed to receive the microdroplets dispensed by the inkjet dispenser and form the nanoparticles therein.

    摘要翻译: 用于形成纳米颗粒的装置和方法采用喷墨分配器和纳米颗粒形成装置。 喷墨分配器包括至少一个孔口。 将具有待转化成纳米尺度的物质的液体溶液接收在喷墨分配器中,并从至少一个孔口分配以产生多个微滴。 纳米颗粒形成装置设置成接收由喷墨分配器分配的微滴并在其中形成纳米颗粒。

    Methods for mapping genetic mutations
    4.
    发明授权
    Methods for mapping genetic mutations 失效
    绘制遗传突变的方法

    公开(公告)号:US5459039A

    公开(公告)日:1995-10-17

    申请号:US334612

    申请日:1994-03-18

    IPC分类号: C12N15/00 C12N15/10 C12Q1/68

    摘要: The present invention relates to a method for detecting base sequence differences within homologous regions of two DNA molecules comprising the steps of contacting at least one strand of the first DNA molecule with the complementary strand of the second DNA molecule under conditions such that base pairing occurs, contacting the resulting DNA duplexes with a protein that recognizes substantially all base pair mismatches under conditions such that the protein forms specific complexes with its cognate mispairs, and detecting the resulting DNA:protein complexes by a suitable analytical method. Also disclosed are protein components of DNA mismatch correction systems and the use of these components in methods for genetic mapping.

    摘要翻译: 本发明涉及一种用于检测两个DNA分子的同源区域内的碱基序列差异的方法,包括以下步骤:在发生碱基配对的条件下使第一DNA分子的至少一条链与第二DNA分子的互补链接触, 使得到的DNA双链体与蛋白质接触,所述蛋白质在条件下识别基本上所有的碱基对错配,使得蛋白质与其同源的错配形成特异性复合物,并通过合适的分析方法检测所得的DNA:蛋白质复合物。 还公开了DNA错配校正系统的蛋白质组分以及这些组分在遗传作图方法中的应用。

    Method of analysis and manipulation of DNA utilizing mismatch repair
systems
    5.
    发明授权
    Method of analysis and manipulation of DNA utilizing mismatch repair systems 失效
    使用错配修复系统分析和操纵DNA的方法

    公开(公告)号:US6008031A

    公开(公告)日:1999-12-28

    申请号:US896518

    申请日:1997-06-17

    IPC分类号: C12N9/24 C12Q1/68

    摘要: A diagnostic method for detecting a base pair mismatch in a DNA duplex, comprising the steps of contacting at least one strand of a first DNA molecule with the complementary strand of a second DNA molecule under conditions such that base pairing occurs contacting a DNA duplex potentially containing a base pair mismatch with a mispair recognition protein under conditions suitable for the protein to form a specific complex only with the DNA duplex having a base pair mismatch, and not with a DNA duplex lacking a base pair mismatch, and detecting any complex as a measure of the presence of a base pair mismatch in the DNA duplex.

    摘要翻译: 一种用于检测DNA双链体中碱基对失配的诊断方法,包括以下步骤:使第一DNA分子的至少一条链与第二DNA分子的互补链接触,使得碱基配对发生接触可能含有 在适合蛋白质形成特异性复合物的条件下,与不匹配的DNA双链体不匹配的碱基对与错配识别蛋白质不匹配,而不与缺乏碱基对失配的DNA双链体,并且检测任何复合物作为测量 在DNA双链体中存在碱基对错配。