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公开(公告)号：US07932270B2
公开(公告)日：2011-04-26
申请号：US11888625
申请日：2007-07-31
申请人： Pu-Ping Lu , Xiangping Qian , Jeffrey T. Finer , Chihyuan (Grace) Chuang , Bradley P. Morgan , David J. Morgans, Jr.
发明人： Pu-Ping Lu , Xiangping Qian , Jeffrey T. Finer , Chihyuan (Grace) Chuang , Bradley P. Morgan , David J. Morgans, Jr.
IPC分类号： C07D401/14 , A61K31/44
CPC分类号： C07D401/14 , C07D213/82 , C07D401/12 , C07D405/14
摘要： Chemical entities that modulate smooth muscle myosin and/or non-muscle myosin, and chemical entities, pharmaceutical compositions and methods of treatment of diseases and conditions associated with smooth muscle myosin and/or non-muscle myosin are described.
摘要翻译： 描述了调节平滑肌肌球蛋白和/或非肌肉肌球蛋白的化学实体以及与平滑肌肌球蛋白和/或非肌肉肌球蛋白相关的疾病和病症的化学实体，药物组合物和治疗方法。
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公开(公告)号：US07919511B2
公开(公告)日：2011-04-05
申请号：US11888655
申请日：2007-07-31
申请人： Pu-Ping Lu , Xiangping Qian , Jeffrey T. Finer , Chihyuan (Grace) Chuang , Bradley P. Morgan , David J. Morgans, Jr.
发明人： Pu-Ping Lu , Xiangping Qian , Jeffrey T. Finer , Chihyuan (Grace) Chuang , Bradley P. Morgan , David J. Morgans, Jr.
IPC分类号： C07D421/02 , A61K31/44
CPC分类号： A61K31/44 , C07D213/82
摘要： Chemical entities that modulate smooth muscle myosin and/or non-muscle myosin, and chemical entities, pharmaceutical compositions and methods of treatment of diseases and conditions associated with smooth muscle myosin and/or non-muscle myosin are described.
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公开(公告)号：US08063082B2
公开(公告)日：2011-11-22
申请号：US11888903
申请日：2007-08-01
申请人： Xiangping Qian , Jeffrey T. Finer , Pu-Ping Lu , Chihyuan (Grace) Chuang , Bradley P. Morgan , David J. Morgans, Jr.
发明人： Xiangping Qian , Jeffrey T. Finer , Pu-Ping Lu , Chihyuan (Grace) Chuang , Bradley P. Morgan , David J. Morgans, Jr.
IPC分类号： A61K31/41 , C07D257/04
CPC分类号： C07D257/04 , C07D403/10
摘要： Chemical entities that modulate smooth muscle myosin and/or non-muscle myosin, pharmaceutical compositions and methods of treatment of diseases and conditions associated with smooth muscle myosin and/or non-muscle myosin are described.
摘要翻译： 描述了调节平滑肌肌球蛋白和/或非肌肉肌球蛋白的化学实体，治疗与平滑肌肌球蛋白和/或非肌肉肌球蛋白相关的疾病和病症的药物组合物和方法。
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公开(公告)号：US20090012126A1
公开(公告)日：2009-01-08
申请号：US11888625
申请日：2007-07-31
申请人： Pu-Ping Lu , Xiangping Qian , Jeffrey T. Finer , Chihyuan (Grace) Chuang , Bradley P. Morgan , David J. Morgans, JR.
发明人： Pu-Ping Lu , Xiangping Qian , Jeffrey T. Finer , Chihyuan (Grace) Chuang , Bradley P. Morgan , David J. Morgans, JR.
IPC分类号： A61K31/444 , C07D213/50 , C07D401/02 , A61K31/4439 , A61K31/44 , C07D401/14 , C07D211/74 , A61P21/00
CPC分类号： C07D401/14 , C07D213/82 , C07D401/12 , C07D405/14
摘要： Chemical entities that modulate smooth muscle myosin and/or non-muscle myosin, and chemical entities, pharmaceutical compositions and methods of treatment of diseases and conditions associated with smooth muscle myosin and/or non-muscle myosin are described.
摘要翻译： 描述了调节平滑肌肌球蛋白和/或非肌肉肌球蛋白的化学实体以及与平滑肌肌球蛋白和/或非肌肉肌球蛋白相关的疾病和病症的化学实体，药物组合物和治疗方法。
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公开(公告)号：US20130053348A1
公开(公告)日：2013-02-28
申请号：US13612713
申请日：2012-09-12
申请人： Xiangping Qian , Chihyuan (Grace) Chuang , Pu-Ping Lu , Sing Yao , Qing (Kevin) Lu , Hong Jiang , Wenyue Wang , Bradley P. Morgan , David J. Morgans, JR.
发明人： Xiangping Qian , Chihyuan (Grace) Chuang , Pu-Ping Lu , Sing Yao , Qing (Kevin) Lu , Hong Jiang , Wenyue Wang , Bradley P. Morgan , David J. Morgans, JR.
IPC分类号： A61K31/472 , C07F9/62 , A61K31/675 , C07D401/12 , A61K31/496 , C07D471/04 , A61K31/4375 , C07D487/04 , A61K31/4985 , A61K31/437 , C07D413/12 , A61K31/5377 , A61K31/551 , A61K31/655 , A61P21/00 , A61P9/12 , A61P11/06 , A61P11/00 , A61P27/06 , A61P1/00 , A61P13/10 , A61P27/02 , A61P7/04 , A61P15/00 , C07D217/22
CPC分类号： C07H21/04 , C07D213/75 , C07D217/22 , C07D261/14 , C07D277/82 , C07D401/12 , C07D471/04 , C07D487/04
摘要： Chemical entities that modulate smooth muscle myosin and/or non-muscle myosin, pharmaceutical compositions and methods of treatment of diseases and conditions associated with smooth muscle myosin and/or non-muscle myosin are described.
摘要翻译： 描述了调节平滑肌肌球蛋白和/或非肌肉肌球蛋白的化学实体，治疗与平滑肌肌球蛋白和/或非肌肉肌球蛋白相关的疾病和病症的药物组合物和方法。
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公开(公告)号：US07939534B2
公开(公告)日：2011-05-10
申请号：US11888672
申请日：2007-07-31
申请人： Pu-Ping Lu , Xiangping Qian , Chihyuan (Grace) Chuang , Bradley P. Morgan , David J. Morgans, Jr.
发明人： Pu-Ping Lu , Xiangping Qian , Chihyuan (Grace) Chuang , Bradley P. Morgan , David J. Morgans, Jr.
IPC分类号： C07D401/14 , A61K31/44
CPC分类号： C07D401/14 , C07D401/04 , C07D405/14 , C07D413/14
摘要： Chemical entities that modulate smooth muscle myosin and/or non-muscle myosin, and chemical entities, pharmaceutical compositions and methods of treatment of diseases and conditions associated with smooth muscle myosin and/or non-muscle myosin are described.
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公开(公告)号：US20090275537A1
公开(公告)日：2009-11-05
申请号：US12228421
申请日：2008-08-11
申请人： Xiangping Qian , Chihyuan (Grace) Chuang , Pu-Ping Lu , Bing Yao , Qing (Kevin) Lu , Hong Jiang , Wenyue Wang , Bradley P. Morgan , David J. Morgans, JR.
发明人： Xiangping Qian , Chihyuan (Grace) Chuang , Pu-Ping Lu , Bing Yao , Qing (Kevin) Lu , Hong Jiang , Wenyue Wang , Bradley P. Morgan , David J. Morgans, JR.
IPC分类号： A61K31/675 , C07D217/22 , A61K31/47 , A61K31/496 , A61K31/44 , A61K31/4375 , A61K31/4985 , A61P11/06 , A61P25/00 , A61P21/00 , A61P1/00 , A61P9/12 , C07D487/02 , C07D471/02 , C07D213/02 , C07D401/02 , C07F9/06
CPC分类号： C07H21/04 , C07D213/75 , C07D217/22 , C07D261/14 , C07D277/82 , C07D401/12 , C07D471/04 , C07D487/04
摘要： Chemical entities that modulate smooth muscle myosin and/or non-muscle myosin, pharmaceutical compositions and methods of treatment of diseases and conditions associated with smooth muscle myosin and/or non-muscle myosin are described.
摘要翻译： 描述了调节平滑肌肌球蛋白和/或非肌肉肌球蛋白的化学实体，治疗与平滑肌肌球蛋白和/或非肌肉肌球蛋白相关的疾病和病症的药物组合物和方法。
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公开(公告)号：US08895582B2
公开(公告)日：2014-11-25
申请号：US13612713
申请日：2012-09-12
申请人： Xiangping Qian , Chihyuan (Grace) Chuang , Pu-Ping Lu , Bing Yao , Qing (Kevin) Lu , Hong Jiang , Wenyue Wang , Bradley P. Morgan , David J. Morgans, Jr.
发明人： Xiangping Qian , Chihyuan (Grace) Chuang , Pu-Ping Lu , Bing Yao , Qing (Kevin) Lu , Hong Jiang , Wenyue Wang , Bradley P. Morgan , David J. Morgans, Jr.
IPC分类号： C07D217/22 , A61K31/472 , C07H21/04 , C07D401/12 , C07D487/04 , C07D213/75 , C07D261/14 , C07D277/82 , C07D471/04
CPC分类号： C07H21/04 , C07D213/75 , C07D217/22 , C07D261/14 , C07D277/82 , C07D401/12 , C07D471/04 , C07D487/04
摘要： Chemical entities that modulate smooth muscle myosin and/or non-muscle myosin, pharmaceutical compositions and methods of treatment of diseases and conditions associated with smooth muscle myosin and/or non-muscle myosin are described.
摘要翻译： 描述了调节平滑肌肌球蛋白和/或非肌肉肌球蛋白的化学实体，治疗与平滑肌肌球蛋白和/或非肌肉肌球蛋白相关的疾病和病症的药物组合物和方法。
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公开(公告)号：US08759374B2
公开(公告)日：2014-06-24
申请号：US13308287
申请日：2011-11-30
申请人： Xiangping Qian , Chihyuan (Grace) Chuang , Pu-Ping Lu , Bing Yao , Qing (Kevin) Lu , Hong Jiang , Wenyue Wang , Bradley P. Morgan , David J. Morgans, Jr.
发明人： Xiangping Qian , Chihyuan (Grace) Chuang , Pu-Ping Lu , Bing Yao , Qing (Kevin) Lu , Hong Jiang , Wenyue Wang , Bradley P. Morgan , David J. Morgans, Jr.
IPC分类号： C07D217/22 , A61K31/44
CPC分类号： C07H21/04 , C07D213/75 , C07D217/22 , C07D261/14 , C07D277/82 , C07D401/12 , C07D471/04 , C07D487/04
摘要： Chemical entities that modulate smooth muscle myosin and/or non-muscle myosin, pharmaceutical compositions and methods of treatment of diseases and conditions associated with smooth muscle myosin and/or non-muscle myosin are described.
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公开(公告)号：US08071625B2
公开(公告)日：2011-12-06
申请号：US11888892
申请日：2007-08-01
申请人： Xiangping Qian , Pu-Ping Lu , Chihyuan (Grace) Chuang , Bradley P. Morgan , David J. Morgans, Jr.
发明人： Xiangping Qian , Pu-Ping Lu , Chihyuan (Grace) Chuang , Bradley P. Morgan , David J. Morgans, Jr.
IPC分类号： A61K31/445 , C07D211/06 , C07D309/02
CPC分类号： C07C275/24 , C07C271/28 , C07D207/09 , C07D211/06
摘要： Chemical entities that modulate smooth muscle myosin and/or non-muscle myosin, pharmaceutical compositions and methods of treatment of diseases and conditions associated with smooth muscle myosin and/or non-muscle myosin are described.
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