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1.发明授权公开(公告)号：US11236098B2
公开(公告)日：2022-02-01
申请号：US17202320
申请日：2021-03-15
发明人： Robert Chapman , Lonn S. Rider , Qi Hong , Robert Kupper , Donald J. Kyle
IPC分类号： A61K31/485 , C07D489/08 , C07D489/02 , A61K9/20 , A61K9/48 , A61K9/14 , C07D489/04
摘要： In certain embodiments the invention is directed to a process for preparing an oxycodone hydrochloride composition having less than 25 ppm of 14-hydroxycodeinone.
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公开(公告)号：US11738023B2
公开(公告)日：2023-08-29
申请号：US17195434
申请日：2021-03-08
申请人： Purdue Pharma L.P.
IPC分类号： A61K31/498 , A61P25/20 , A61M21/00
CPC分类号： A61K31/498 , A61P25/20 , A61M21/00
摘要： The disclosure relates to methods for treating or preventing a sleep disorder by administering a compound of formula (1)(1), or a compound of formula (1A), (1B), (1C), (1D), (1E), or (1F) to an animal in need of such treatment. In certain embodiments, such compounds effectively treat or prevent a sleep disorder in the animal, while producing reduced side effects compared to previously available compounds.
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公开(公告)号：US10974081B2
公开(公告)日：2021-04-13
申请号：US16318686
申请日：2017-07-25
申请人： Purdue Pharma L.P.
IPC分类号： A61P25/20 , A61K31/498 , A61M21/00
摘要： The disclosure relates to methods for treating or preventing a sleep disorder by administering a compound of formula (1)(1), or a compound of formula (1A), (1B), (1C), (1D), (1E), or (1F) to an animal in need of such treatment. In certain embodiments, such compounds effectively treat or prevent a sleep disorder in the animal, while producing reduced side effects compared to previously available compounds.
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公开(公告)号：US09884059B2
公开(公告)日：2018-02-06
申请号：US14669481
申请日：2015-03-26
申请人： Purdue Pharma L.P.
发明人： Michele Hummel , Donald J. Kyle , Garth Whiteside
IPC分类号： A61K31/44 , A61K31/485 , A61K38/07 , A61K31/135 , A61K31/4468 , A61K31/451 , A61K31/4748 , A61K31/137 , A61K31/05 , A61K9/70 , A61K9/00 , A61K9/16 , A61K9/24
CPC分类号： A61K31/485 , A61K9/0019 , A61K9/167 , A61K9/209 , A61K9/7023 , A61K31/05 , A61K31/135 , A61K31/137 , A61K31/4468 , A61K31/451 , A61K31/4748 , A61K38/07 , A61K2300/00 , A61K31/00 , A61K31/138
摘要： Disclosed in certain embodiments is a method of treating or preventing an opioid-induced adverse pharmacodynamic response comprising administering to a patient in need thereof an effective amount of buprenorphine.
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公开(公告)号：US09849124B2
公开(公告)日：2017-12-26
申请号：US14885597
申请日：2015-10-16
申请人： Purdue Pharma L.P.
发明人： Michele Hummel , Donald J. Kyle , Garth Whiteside
IPC分类号： A61K31/485 , A61K9/20 , A61K9/48 , A61K9/70
CPC分类号： A61K31/485 , A61K9/2004 , A61K9/4816 , A61K9/7023 , A61K2300/00
摘要： Disclosed in certain embodiments is a method of treating or preventing an opioid induced adverse pharmacodynamic response comprising administering to a patient in need thereof an effective amount of buprenorphine.
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公开(公告)号：US20170340646A1
公开(公告)日：2017-11-30
申请号：US15680737
申请日：2017-08-18
申请人： Purdue Pharma L.P.
IPC分类号： A61K31/55 , A61K38/31 , A61K31/785 , A61K31/702 , A61K31/519 , A61K31/505 , A61K31/501 , A61K45/06 , A61K31/40
CPC分类号： A61K31/55 , A61K31/40 , A61K31/501 , A61K31/505 , A61K31/519 , A61K31/702 , A61K31/785 , A61K38/31 , A61K45/06 , A61K2300/00 , A61K36/31
摘要： Disclosed in certain embodiments is a method of decreasing gastric emptying comprising administering to a subject an effective amount of a sodium-channel blocker to decrease gastric emptying.
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公开(公告)号：US09662326B2
公开(公告)日：2017-05-30
申请号：US14632152
申请日：2015-02-26
申请人： Purdue Pharma L.P.
发明人： Michele Hummel , Donald J. Kyle , Garth Whiteside
IPC分类号： A61K31/44 , A61K31/485 , A61K38/07 , A61K31/135 , A61K31/4468 , A61K31/451 , A61K31/4748 , A61K31/137 , A61K9/70 , A61K9/00 , A61K9/16 , A61K9/24
CPC分类号： A61K31/485 , A61K9/0019 , A61K9/167 , A61K9/209 , A61K9/7023 , A61K31/05 , A61K31/135 , A61K31/137 , A61K31/4468 , A61K31/451 , A61K31/4748 , A61K38/07 , A61K2300/00 , A61K31/00 , A61K31/138
摘要： Disclosed in certain embodiments is a method of treating or preventing an opioid-induced adverse pharmacodynamic response comprising administering to a patient in need thereof an effective amount of buprenorphine.
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公开(公告)号：US20160243129A1
公开(公告)日：2016-08-25
申请号：US15048530
申请日：2016-02-19
申请人： Purdue Pharma L.P.
IPC分类号： A61K31/55 , A61K31/519 , A61K31/501 , A61K31/505 , A61K31/40
CPC分类号： A61K31/55 , A61K31/40 , A61K31/501 , A61K31/505 , A61K31/519 , A61K31/702 , A61K31/785 , A61K38/31 , A61K45/06 , A61K2300/00 , A61K36/31
摘要： Disclosed in certain embodiments is a method of decreasing gastric emptying comprising administering to a subject an effective amount of a sodium-channel blocker to decrease gastric emptying.
摘要翻译： 在某些实施方案中公开的是减少胃排空的方法，包括向受试者施用有效量的钠通道阻滞剂以减少胃排空。
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公开(公告)号：US20130303561A1
公开(公告)日：2013-11-14
申请号：US13864791
申请日：2013-04-17
申请人： Purdue Pharma L.P.
IPC分类号： A61K31/485
CPC分类号： A61K31/485 , A61K9/0019 , A61K9/167 , A61K9/209 , A61K9/7023 , A61K31/05 , A61K31/135 , A61K31/137 , A61K31/4468 , A61K31/451 , A61K31/4748 , A61K38/07 , A61K2300/00 , A61K31/00 , A61K31/138
摘要： Disclosed in certain embodiments is a method of treating or preventing an opioid-induced adverse pharmacodynamic response comprising administering to a patient in need thereof an effective amount of buprenorphine.
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公开(公告)号：US20240350479A1
公开(公告)日：2024-10-24
申请号：US18436555
申请日：2024-02-08
申请人： Purdue Pharma L.P.
发明人： Michele Hummel , Donald J. Kyle , Garth Whiteside
IPC分类号： A61K31/485 , A61K9/00 , A61K9/16 , A61K9/24 , A61K9/70 , A61K31/05 , A61K31/135 , A61K31/137 , A61K31/445 , A61K31/4468 , A61K31/451 , A61K31/4748 , A61K38/07
CPC分类号： A61K31/485 , A61K31/135 , A61K31/137 , A61K31/4468 , A61K31/451 , A61K31/4748 , A61K38/07 , A61K9/0019 , A61K9/167 , A61K9/209 , A61K9/7023 , A61K31/05 , A61K31/445
摘要： Disclosed in certain embodiments is a method of treating or preventing an opioid-induced adverse pharmacodynamic response comprising administering to a patient in need thereof an effective amount of buprenorphine.
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