公开(公告)号：US06275731B1

公开(公告)日：2001-08-14

申请号：US09474193

申请日：1999-12-29

申请人： Qingsheng Zhu ,  Jungkuk Kim ,  Arthur Olive ,  Jan-Pieter Heemels

发明人： Qingsheng Zhu ,  Jungkuk Kim ,  Arthur Olive ,  Jan-Pieter Heemels

IPC分类号： A61N1365

CPC分类号： A61N1/3712

摘要： A method for reducing the affects of intrinsic detection latency in a cardiac rhythm management device, wherein said method is initiated immediately prior to delivering a stimulation pulse to the heart tissue. A coincidence of intrinsic and cardiac rhythm management initiated stimulus or the delivery of a stimulation pulse proximate the time of an intrinsic event due to intrinsic detection latency may results in delivery of unnecessary backup stimulus and/or imprecise determination of a pacing threshold. When stimulating the heart, the timing sequence for delivering a stimulation pulse typically depends upon the timing of a previous intrinsic or device initiated event. Further, the method of the present invention reduces the affects of intrinsic detection latency thereby facilitating improved detection of capture and determination of capture threshold for minimizing power consumption while assuring therapeutic efficacy.

摘要翻译： 一种减轻心律管理装置中内在检测延迟的影响的方法，其中所述方法在将刺激脉冲传递到心脏组织之前立即开始。 由于内在的检测潜伏期，固有和心律管理发起的刺激或接近内在事件时间的刺激脉冲的传递的巧合可能导致递送不必要的备份刺激和/或不精确地确定起搏阈值。 当刺激心脏时，用于递送刺激脉冲的定时序列通常取决于先前的固有或设备启动事件的时序。 此外，本发明的方法减少了内在检测潜能的影响，从而有助于提高捕获捕获阈值的检测和捕获阈值的确定，以最大限度地降低功耗，同时确保治疗效果。

公开(公告)号：US6038474A

公开(公告)日：2000-03-14

申请号：US260943

申请日：1999-03-02

申请人： Qingsheng Zhu ,  Jungkuk Kim ,  Arthur Olive ,  Jan-Pieter Heemels

发明人： Qingsheng Zhu ,  Jungkuk Kim ,  Arthur Olive ,  Jan-Pieter Heemels

IPC分类号： A61N1/37 ,  A61N1/365

CPC分类号： A61N1/3712

摘要： A method for reducing the affects of intrinsic detection latency in a cardiac rhythm management device, wherein said method is initiated immediately prior to delivering a stimulation pulse to the heart tissue. A coincidence of intrinsic and cardiac rhythm management initiated stimulus or the delivery of a stimulation pulse proximate the time of an intrinsic event due to intrinsic detection latency may results in delivery of unnecessary backup stimulus and/or imprecise determination of a pacing threshold. When stimulating the heart, the timing sequence for delivering a stimulation pulse typically depends upon the timing of a previous intrinsic or device initiated event. Further, the method of the present invention reduces the affects of intrinsic detection latency thereby facilitating improved detection of capture and determination of capture threshold for minimizing power consumption while assuring therapeutic efficacy.

摘要翻译： 一种减轻心律管理装置中内在检测延迟的影响的方法，其中所述方法在将刺激脉冲传递到心脏组织之前立即开始。 由于内在的检测潜伏期，固有和心律管理发起的刺激或接近内在事件时间的刺激脉冲的传递的巧合可能导致递送不必要的备份刺激和/或不精确地确定起搏阈值。 当刺激心脏时，用于递送刺激脉冲的定时序列通常取决于先前的固有或设备启动事件的时序。 此外，本发明的方法减少了内在检测潜能的影响，从而有助于提高捕获捕获阈值的检测和捕获阈值的确定，以最大限度地降低功耗，同时确保治疗效果。

公开(公告)号：US20050137490A1

公开(公告)日：2005-06-23

申请号：US11037276

申请日：2005-01-18

申请人： Avram Scheiner ,  Qingsheng Zhu ,  Arthur Olive ,  Don Villalta

发明人： Avram Scheiner ,  Qingsheng Zhu ,  Arthur Olive ,  Don Villalta

IPC分类号： A61B5/00 ,  A61B5/042 ,  A61B5/044 ,  A61B5/0452 ,  A61B7/02 ,  A61B5/02

CPC分类号： A61B7/04 ,  A61B5/0002 ,  A61B5/0031 ,  A61B5/04012 ,  A61B5/04014 ,  A61B5/0402 ,  A61B5/042 ,  A61B5/044 ,  A61B5/0452 ,  A61B5/1118 ,  A61B5/742 ,  A61B7/023 ,  G06F19/00

摘要： An apparatus for outputting heart sounds includes an implantable system and an external system. The implantable system includes a sensor for generating sensed signals representing detected heart sounds, an interface circuit and a control circuit for receiving the sensed signals, generating data representing the heart sounds therefrom, and transmitting the data to the external system via the interface circuit. The external system includes an interface circuit for communicating with the implantable system, and a control circuit for receiving the data representing the heart sounds and for generating control signals that cause an output device to generate outputs representing the sounds. The implantable system may also include a sensor(s) for detecting cardiac electrical signals. In this case, outputs representing the cardiac electrical signals are also output.

摘要翻译： 用于输出心音的装置包括可植入系统和外部系统。 可植入系统包括用于产生表示检测到的心音的感测信号的传感器，接口电路和用于接收感测信号的控制电路，产生表示心音的数据，以及经由接口电路将数据发送到外部系统。 外部系统包括用于与可植入系统进行通信的接口电路，以及用于接收表示心脏声音的数据的控制电路，以及用于产生使输出设备产生表示声音的输出的控制信号。 可植入系统还可以包括用于检测心脏电信号的传感器。 在这种情况下，还输出表示心电信号的输出。

公开(公告)号：US06192275B1

公开(公告)日：2001-02-20

申请号：US09309925

申请日：1999-05-11

申请人： Qingsheng Zhu ,  Mark Gryzwa ,  Geng Zhang ,  Arthur Olive

发明人： Qingsheng Zhu ,  Mark Gryzwa ,  Geng Zhang ,  Arthur Olive

IPC分类号： A61N1362

CPC分类号： A61N1/3712

摘要： An implantable cardiac rhythm management device adapted to receive and digitize electrocardiogram signals from leads placed on or in the heart and capable of automatically adjusting an evoked response detection threshold dependent upon a modulation of the amplitude of the evoked response. Respiration, activity level, and lead maturation, among others, all effect the modulation of the evoked response and the amplitude of a signal associated with evoked response. The present invention automatically adjusts the evoked response detection threshold to account for this modulation. Without limitation, the automatic adjustment of the evoked response detection threshold may be utilized during an automatic capture verification sequence. In the event of non-capture or fusion beats during an automatic adjustment, the evoked response detection threshold is not adjusted.

摘要翻译： 一种植入式心律管理装置，适于从放置在心脏上或心脏上的引线接收和数字化心电图信号，并且能够根据诱发反应的振幅的调制来自动调整诱发响应检测阈值。 呼吸，活动水平和铅成熟等都影响诱发反应的调制和与诱发反应相关的信号的振幅。 本发明自动调整诱发响应检测阈值以解决该调制。 不受限制，可以在自动捕获验证序列期间利用诱发响应检测阈值的自动调整。 在自动调整期间不捕获或融合跳动的情况下，不调整诱发响应检测阈值。