公开(公告)号：US07766842B2

公开(公告)日：2010-08-03

申请号：US11890404

申请日：2007-08-06

申请人： Quan Ni ,  John D. Hatlestad ,  Jesse W. Hartley ,  Jeff E. Stahmann ,  Jaeho Kim ,  Kent Lee

发明人： Quan Ni ,  John D. Hatlestad ,  Jesse W. Hartley ,  Jeff E. Stahmann ,  Jaeho Kim ,  Kent Lee

IPC分类号： A61B5/00

CPC分类号： A61B5/4818 ,  A61B5/0205 ,  A61B5/4806 ,  A61B5/4809 ,  A61B5/7264

摘要： Devices and methods for detecting disordered breathing involve determining that the patient is asleep and sensing one or more signals associated with disordered breathing indicative of sleep-disordered breathing while the patient is asleep. Sleep-disordered breathing is detected using the sensed signals associated with disordered breathing. The sensed signals associated with disordered breathing may also be used to acquire a respiration pattern of one or more respiration cycles. Characteristics of the respiration pattern are determined. The respiration pattern is classified as a disordered breathing episode based on the characteristics of the respiration pattern. One or more processes involved in the detection of disordered breathing are performed using an implantable device.

摘要翻译： 用于检测无序呼吸的装置和方法涉及确定患者睡着并且感测与患者睡着时指示睡眠呼吸紊乱的无序呼吸相关联的一个或多个信号。 使用与无序呼吸相关的感测信号来检测睡眠呼吸障碍。 与无序呼吸相关联的感测信号也可用于获取一个或多个呼吸循环的呼吸模式。 确定呼吸模式的特征。 根据呼吸模式的特点，呼吸模式被分类为无序呼吸发作。 使用可植入装置进行涉及无序呼吸检测的一个或多个过程。

公开(公告)号：US20100324438A1

公开(公告)日：2010-12-23

申请号：US12847711

申请日：2010-07-30

申请人： Quan Ni ,  John D. Hatlestad ,  Jesse W. Hartley ,  Jeff E. Stahmann ,  Jaeho Kim ,  Kent Lee

发明人： Quan Ni ,  John D. Hatlestad ,  Jesse W. Hartley ,  Jeff E. Stahmann ,  Jaeho Kim ,  Kent Lee

IPC分类号： A61B5/08

CPC分类号： A61B5/4818 ,  A61B5/0205 ,  A61B5/4806 ,  A61B5/4809 ,  A61B5/7264

摘要： Devices and methods for detecting disordered breathing involve determining that the patient is asleep and sensing one or more signals associated with disordered breathing indicative of sleep-disordered breathing while the patient is asleep. Sleep-disordered breathing is detected using the sensed signals associated with disordered breathing. The sensed signals associated with disordered breathing may also be used to acquire a respiration pattern of one or more respiration cycles. Characteristics of the respiration pattern are determined. The respiration pattern is classified as a disordered breathing episode based on the characteristics of the respiration pattern. One or more processes involved in the detection of disordered breathing are performed using an implantable device.

摘要翻译： 用于检测无序呼吸的装置和方法涉及确定患者睡着并且感测与患者睡着时指示睡眠呼吸紊乱的无序呼吸相关联的一个或多个信号。 使用与无序呼吸相关的感测信号来检测睡眠呼吸障碍。 与无序呼吸相关联的感测信号也可用于获取一个或多个呼吸循环的呼吸模式。 确定呼吸模式的特征。 根据呼吸模式的特点，呼吸模式被分类为无序呼吸发作。 使用可植入装置进行涉及无序呼吸检测的一个或多个过程。

公开(公告)号：US07252640B2

公开(公告)日：2007-08-07

申请号：US10309770

申请日：2002-12-04

申请人： Quan Ni ,  John D. Hatlestad ,  Jesse W. Hartley ,  Jeff E. Stahmann ,  Jaeho Kim ,  Kent Lee

发明人： Quan Ni ,  John D. Hatlestad ,  Jesse W. Hartley ,  Jeff E. Stahmann ,  Jaeho Kim ,  Kent Lee

IPC分类号： A61B5/02

CPC分类号： A61B5/4818 ,  A61B5/0205 ,  A61B5/4806 ,  A61B5/4809 ,  A61B5/7264

摘要： Devices and methods for detecting disordered breathing involve determining that the patient is asleep and sensing one or more signals associated with disordered breathing indicative of sleep-disordered breathing while the patient is asleep. Sleep-disordered breathing is detected using the sensed signals associated with disordered breathing. The sensed signals associated with disordered breathing may also be used to acquire a respiration pattern of one or more respiration cycles. Characteristics of the respiration pattern are determined. The respiration pattern is classified as a disordered breathing episode based on the characteristics of the respiration pattern. One or more processes involved in the detection of disordered breathing are performed using an implantable device.

公开(公告)号：US08475388B2

公开(公告)日：2013-07-02

申请号：US12847711

申请日：2010-07-30

申请人： Quan Ni ,  John D. Hatlestad ,  Jesse W. Hartley ,  Jeffrey E. Stahmann ,  Jaeho Kim ,  Kent Lee

发明人： Quan Ni ,  John D. Hatlestad ,  Jesse W. Hartley ,  Jeffrey E. Stahmann ,  Jaeho Kim ,  Kent Lee

IPC分类号： A61B5/08

CPC分类号： A61B5/4818 ,  A61B5/0205 ,  A61B5/4806 ,  A61B5/4809 ,  A61B5/7264

摘要： Devices and methods for detecting disordered breathing involve determining that the patient is asleep and sensing one or more signals associated with disordered breathing indicative of sleep-disordered breathing while the patient is asleep. Sleep-disordered breathing is detected using the sensed signals associated with disordered breathing. The sensed signals associated with disordered breathing may also be used to acquire a respiration pattern of one or more respiration cycles. Characteristics of the respiration pattern are determined. The respiration pattern is classified as a disordered breathing episode based on the characteristics of the respiration pattern. One or more processes involved in the detection of disordered breathing are performed using an implantable device.

摘要翻译： 用于检测无序呼吸的装置和方法涉及确定患者睡着并且感测与患者睡着时指示睡眠呼吸紊乱的无序呼吸相关联的一个或多个信号。 使用与无序呼吸相关的感测信号来检测睡眠呼吸障碍。 与无序呼吸相关联的感测信号也可用于获取一个或多个呼吸循环的呼吸模式。 确定呼吸模式的特征。 根据呼吸模式的特点，呼吸模式被分类为无序呼吸发作。 使用可植入装置进行涉及无序呼吸检测的一个或多个过程。

公开(公告)号：US20070282215A1

公开(公告)日：2007-12-06

申请号：US11890404

申请日：2007-08-06

申请人： Quan Ni ,  John Hatlestad ,  Jesse Hartley ,  Jeff Stahmann ,  Jaeho Kim ,  Kent Lee

发明人： Quan Ni ,  John Hatlestad ,  Jesse Hartley ,  Jeff Stahmann ,  Jaeho Kim ,  Kent Lee

IPC分类号： A61B5/02

CPC分类号： A61B5/4818 ,  A61B5/0205 ,  A61B5/4806 ,  A61B5/4809 ,  A61B5/7264

摘要： Devices and methods for detecting disordered breathing involve determining that the patient is asleep and sensing one or more signals associated with disordered breathing indicative of sleep-disordered breathing while the patient is asleep. Sleep-disordered breathing is detected using the sensed signals associated with disordered breathing. The sensed signals associated with disordered breathing may also be used to acquire a respiration pattern of one or more respiration cycles. Characteristics of the respiration pattern are determined. The respiration pattern is classified as a disordered breathing episode based on the characteristics of the respiration pattern. One or more processes involved in the detection of disordered breathing are performed using an implantable device.

摘要翻译： 用于检测无序呼吸的装置和方法涉及确定患者睡着并且感测与患者睡着时指示睡眠呼吸紊乱的无序呼吸相关联的一个或多个信号。 使用与无序呼吸相关的感测信号来检测睡眠呼吸障碍。 与无序呼吸相关联的感测信号也可用于获取一个或多个呼吸循环的呼吸模式。 确定呼吸模式的特征。 根据呼吸模式的特点，呼吸模式被分类为无序呼吸发作。 使用可植入装置进行涉及无序呼吸检测的一个或多个过程。

公开(公告)号：US08306621B2

公开(公告)日：2012-11-06

申请号：US11676067

申请日：2007-02-16

申请人： Jaeho Kim ,  Quan Ni

发明人： Jaeho Kim ,  Quan Ni

IPC分类号： A61N1/365

CPC分类号： A61B5/0205 ,  A61N1/3601 ,  A61N1/36521 ,  A61N1/37211

摘要： A cardiac rhythm management device for obtaining transthoracic impedance. The device comprises a sensor for obtaining a signal indicative of an action of a heart, an impedance measurement circuit adapted to measure transthoracic impedance and a processor for utilizing the signal indicative of the action of the heart to sample the transthoracic impedance at sampling intervals commenced by fiducial markers in the signal indicative of the action of the heart, where the sampling of the impedance signal removes the component of a stroke volume of the heart from the signal and thereby provides lung ventilation information.

摘要翻译： 用于获得经胸阻抗的心律管理装置。 该装置包括用于获得指示心脏动作的信号的传感器，适于测量经胸阻抗的阻抗测量电路，以及用于利用指示心脏作用的信号以采样间隔采样经脉管阻抗的处理器，采样间隔由 指示心脏动作的信号中的基准标记，其中阻抗信号的采样从信号中去除心脏的搏动体积的分量，从而提供肺通气信息。

公开(公告)号：US20090306486A1

公开(公告)日：2009-12-10

申请号：US12478476

申请日：2009-06-04

申请人： Dan Li ,  Allan C. Shuros ,  Quan Ni ,  Aaron R. McCabe ,  Yunlong Zhang ,  Jaeho Kim

发明人： Dan Li ,  Allan C. Shuros ,  Quan Ni ,  Aaron R. McCabe ,  Yunlong Zhang ,  Jaeho Kim

IPC分类号： A61B5/046 ,  A61B5/02 ,  A61B5/0464

CPC分类号： A61B5/0464 ,  A61B5/0215 ,  A61B5/0422 ,  A61B5/046 ,  A61N1/3622 ,  A61N1/3702

摘要： An apparatus comprises an implantable cardiac signal sensing circuit, configured to provide a sensed near-field depolarization signal from a ventricle and to provide a sensed a far-field intrinsic atrial signal using a far-field atrial sensing channel, and a controller circuit communicatively coupled to the cardiac signal sensing circuit. The controller circuit includes a P-wave detection module configured to detect an atrial depolarization in the sensed far-field intrinsic atrial signal and a tachyarrhythmia detection module configured to detect an episode of tachyarrhythmia using the sensed near-field depolarization signal and to determine whether the tachyarrhythmia episode is indicative of supraventricular tachycardia (SVT) using the detected atrial depolarization and the sensed near-field depolarization signal.

摘要翻译： 一种装置包括可植入心脏信号感测电路，其被配置为提供来自心室的感测的近场去极化信号，并且使用远场心房感测通道提供感测到的远场固有心房信号，以及控制器电路， 到心脏信号感测电路。 所述控制器电路包括P波检测模块，所述P波检测模块被配置为检测所感测的远场固有心房信号中的心房去极化，以及快速性心律失常检测模块，其被配置为使用所感测的近场去极化信号来检测快速性心律失常发作，并且确定是否 快速性心律失常发作指示使用检测到的心房去极化和感测的近场去极化信号的室上性心动过速（SVT）。

公开(公告)号：US20070142867A1

公开(公告)日：2007-06-21

申请号：US11676067

申请日：2007-02-16

申请人： Jaeho Kim ,  Quan Ni

发明人： Jaeho Kim ,  Quan Ni

IPC分类号： A61N1/365

CPC分类号： A61B5/0205 ,  A61N1/3601 ,  A61N1/36521 ,  A61N1/37211

摘要： A cardiac rhythm management device for obtaining transthoracic impedance. The device comprises a sensor for obtaining a signal indicative of an action of a heart, an impedance measurement circuit adapted to measure transthoracic impedance and a processor for utilizing the signal indicative of the action of the heart to sample the transthoracic impedance at sampling intervals commenced by fiducial markers in the signal indicative of the action of the heart, where the sampling of the impedance signal removes the component of a stroke volume of the heart from the signal and thereby provides lung ventilation information.

摘要翻译： 用于获得经胸阻抗的心律管理装置。 该装置包括用于获得指示心脏动作的信号的传感器，适于测量经胸阻抗的阻抗测量电路，以及用于利用指示心脏作用的信号以采样间隔采样经脉管阻抗的处理器，采样间隔由 指示心脏动作的信号中的基准标记，其中阻抗信号的采样从信号中去除心脏的搏动体积的分量，从而提供肺通气信息。

公开(公告)号：US20050004610A1

公开(公告)日：2005-01-06

申请号：US10612388

申请日：2003-07-02

申请人： Jaeho Kim ,  Quan Ni

发明人： Jaeho Kim ,  Quan Ni

IPC分类号： A61N1/365

CPC分类号： A61B5/0205 ,  A61N1/3601 ,  A61N1/36521 ,  A61N1/37211

摘要： A cardiac rhythm management device for obtaining transthoracic impedance. The device comprises a sensor for obtaining a signal indicative of an action of a heart, an impedance measurement circuit adapted to measure transthoracic impedance and a processor for utilizing the signal indicative of the action of the heart to sample the transthoracic impedance at sampling intervals commenced by fiducial markers in the signal indicative of the action of the heart, where the sampling of the impedance signal removes the component of a stroke volume of the heart from the signal and thereby provides lung ventilation information.

摘要翻译： 用于获得经胸阻抗的心律管理装置。 该装置包括用于获得指示心脏动作的信号的传感器，适于测量经胸阻抗的阻抗测量电路，以及用于利用指示心脏作用的信号以采样间隔采样经脉管阻抗的处理器，采样间隔由 指示心脏动作的信号中的基准标记，其中阻抗信号的采样从信号中去除心脏的搏动体积的分量，从而提供肺通气信息。

公开(公告)号：US08401628B2

公开(公告)日：2013-03-19

申请号：US12478476

申请日：2009-06-04

申请人： Dan Li ,  Allan C. Shuros ,  Quan Ni ,  Aaron R. McCabe ,  Yunlong Zhang ,  Jaeho Kim

发明人： Dan Li ,  Allan C. Shuros ,  Quan Ni ,  Aaron R. McCabe ,  Yunlong Zhang ,  Jaeho Kim

IPC分类号： A61B5/024

CPC分类号： A61B5/0464 ,  A61B5/0215 ,  A61B5/0422 ,  A61B5/046 ,  A61N1/3622 ,  A61N1/3702

摘要： An apparatus comprises an implantable cardiac signal sensing circuit, configured to provide a sensed near-field depolarization signal from a ventricle and to provide a sensed a far-field intrinsic atrial signal using a far-field atrial sensing channel, and a controller circuit communicatively coupled to the cardiac signal sensing circuit. The controller circuit includes a P-wave detection module configured to detect an atrial depolarization in the sensed far-field intrinsic atrial signal and a tachyarrhythmia detection module configured to detect an episode of tachyarrhythmia using the sensed near-field depolarization signal and to determine whether the tachyarrhythmia episode is indicative of supraventricular tachycardia (SVT) using the detected atrial depolarization and the sensed near-field depolarization signal.

摘要翻译： 一种装置包括可植入心脏信号感测电路，其被配置为提供来自心室的感测的近场去极化信号，并且使用远场心房感测通道提供感测到的远场固有心房信号，以及控制器电路，其通信耦合 到心脏信号感测电路。 所述控制器电路包括P波检测模块，所述P波检测模块被配置为检测所感测的远场固有心房信号中的心房去极化，以及快速性心律失常检测模块，其被配置为使用所感测的近场去极化信号来检测快速性心律失常发作，并且确定 快速性心律失常发作指示使用检测到的心房去极化和感测的近场去极化信号的室上性心动过速（SVT）。