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1.发明申请SENSING VECTOR CONFIGURATION IN ICD TO ASSIST ARRHYTHMIA DETECTION AND ANNOTATION 有权ICD中的感应矢量配置，以帮助ARRHYTHMIA检测和报告公开(公告)号：US20090306486A1
公开(公告)日：2009-12-10
申请号：US12478476
申请日：2009-06-04
申请人： Dan Li , Allan C. Shuros , Quan Ni , Aaron R. McCabe , Yunlong Zhang , Jaeho Kim
发明人： Dan Li , Allan C. Shuros , Quan Ni , Aaron R. McCabe , Yunlong Zhang , Jaeho Kim
IPC分类号： A61B5/046 , A61B5/02 , A61B5/0464
CPC分类号： A61B5/0464 , A61B5/0215 , A61B5/0422 , A61B5/046 , A61N1/3622 , A61N1/3702
摘要： An apparatus comprises an implantable cardiac signal sensing circuit, configured to provide a sensed near-field depolarization signal from a ventricle and to provide a sensed a far-field intrinsic atrial signal using a far-field atrial sensing channel, and a controller circuit communicatively coupled to the cardiac signal sensing circuit. The controller circuit includes a P-wave detection module configured to detect an atrial depolarization in the sensed far-field intrinsic atrial signal and a tachyarrhythmia detection module configured to detect an episode of tachyarrhythmia using the sensed near-field depolarization signal and to determine whether the tachyarrhythmia episode is indicative of supraventricular tachycardia (SVT) using the detected atrial depolarization and the sensed near-field depolarization signal.
摘要翻译： 一种装置包括可植入心脏信号感测电路，其被配置为提供来自心室的感测的近场去极化信号，并且使用远场心房感测通道提供感测到的远场固有心房信号，以及控制器电路， 到心脏信号感测电路。 所述控制器电路包括P波检测模块，所述P波检测模块被配置为检测所感测的远场固有心房信号中的心房去极化，以及快速性心律失常检测模块，其被配置为使用所感测的近场去极化信号来检测快速性心律失常发作，并且确定是否 快速性心律失常发作指示使用检测到的心房去极化和感测的近场去极化信号的室上性心动过速（SVT）。
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2.发明授权Sensing vector configuration in ICD to assist arrhythmia detection and annotation 有权感应ICD中的矢量配置，以协助心律失常检测和注释公开(公告)号：US08401628B2
公开(公告)日：2013-03-19
申请号：US12478476
申请日：2009-06-04
申请人： Dan Li , Allan C. Shuros , Quan Ni , Aaron R. McCabe , Yunlong Zhang , Jaeho Kim
发明人： Dan Li , Allan C. Shuros , Quan Ni , Aaron R. McCabe , Yunlong Zhang , Jaeho Kim
IPC分类号： A61B5/024
CPC分类号： A61B5/0464 , A61B5/0215 , A61B5/0422 , A61B5/046 , A61N1/3622 , A61N1/3702
摘要： An apparatus comprises an implantable cardiac signal sensing circuit, configured to provide a sensed near-field depolarization signal from a ventricle and to provide a sensed a far-field intrinsic atrial signal using a far-field atrial sensing channel, and a controller circuit communicatively coupled to the cardiac signal sensing circuit. The controller circuit includes a P-wave detection module configured to detect an atrial depolarization in the sensed far-field intrinsic atrial signal and a tachyarrhythmia detection module configured to detect an episode of tachyarrhythmia using the sensed near-field depolarization signal and to determine whether the tachyarrhythmia episode is indicative of supraventricular tachycardia (SVT) using the detected atrial depolarization and the sensed near-field depolarization signal.
摘要翻译： 一种装置包括可植入心脏信号感测电路，其被配置为提供来自心室的感测的近场去极化信号，并且使用远场心房感测通道提供感测到的远场固有心房信号，以及控制器电路，其通信耦合 到心脏信号感测电路。 所述控制器电路包括P波检测模块，所述P波检测模块被配置为检测所感测的远场固有心房信号中的心房去极化，以及快速性心律失常检测模块，其被配置为使用所感测的近场去极化信号来检测快速性心律失常发作，并且确定 快速性心律失常发作指示使用检测到的心房去极化和感测的近场去极化信号的室上性心动过速（SVT）。
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3.发明授权Methods of monitoring hemodynamic status for rhythm discrimination within the heart 有权监测心脏内节律辨别的血液动力学状态的方法公开(公告)号：US08725260B2
公开(公告)日：2014-05-13
申请号：US12366334
申请日：2009-02-05
申请人： Allan C. Shuros , Dan Li , Quan Ni
发明人： Allan C. Shuros , Dan Li , Quan Ni
IPC分类号： A61N1/00
CPC分类号： A61N1/36585 , A61N1/36578
摘要： Systems and methods of performing rhythm discrimination within a patient's body using sensed hemodynamic signals are disclosed. The method can include the steps of receiving an electrical activity signal from an electrode located within or near the heart, detecting an event of the heart based on the received electrical activity signal, sensing one or more mechanical measurements using a sensor located within the body, analyzing a mechanical activity signal received from the sensor, and confirming the type of event based on the mechanical and electrical activity signals. The sensor can comprise a single pressure sensor configured to sense both atrial and ventricular activity within the heart.
摘要翻译： 公开了使用感测到的血液动力学信号在患者体内进行节律辨别的系统和方法。 该方法可以包括以下步骤：从位于心脏内部或附近的电极接收电活动信号，基于接收到的电活动信号检测心脏的事件，使用位于体内的传感器感测一个或多个机械测量， 分析从传感器接收的机械活动信号，以及基于机械和电活动信号来确认事件的类型。 传感器可以包括构造成感测心脏内的心房和心室活动的单个压力传感器。
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4.发明申请METHODS OF MONITORING HEMODYNAMIC STATUS FOR RHYTHM DISCRIMINATION WITHIN THE HEART 有权监测心脏疾病分析的血液动力学状态的方法公开(公告)号：US20090204163A1
公开(公告)日：2009-08-13
申请号：US12366334
申请日：2009-02-05
申请人： Allan C. Shuros , Dan Li , Quan Ni
发明人： Allan C. Shuros , Dan Li , Quan Ni
IPC分类号： A61N1/365
CPC分类号： A61N1/36585 , A61N1/36578
摘要： Systems and methods of performing rhythm discrimination within a patient's body using sensed hemodynamic signals are disclosed. The method can include the steps of receiving an electrical activity signal from an electrode located within or near the heart, detecting an event of the heart based on the received electrical activity signal, sensing one or more mechanical measurements using a sensor located within the body, analyzing a mechanical activity signal received from the sensor, and confirming the type of event based on the mechanical and electrical activity signals. The sensor can comprise a single pressure sensor configured to sense both atrial and ventricular activity within the heart.
摘要翻译： 公开了使用感测到的血液动力学信号在患者体内进行节律辨别的系统和方法。 该方法可以包括以下步骤：从位于心脏内部或附近的电极接收电活动信号，基于接收到的电活动信号检测心脏的事件，使用位于体内的传感器感测一个或多个机械测量， 分析从传感器接收的机械活动信号，以及基于机械和电活动信号来确认事件的类型。 传感器可以包括构造成感测心脏内的心房和心室活动的单个压力传感器。
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公开(公告)号：US20080234773A1
公开(公告)日：2008-09-25
申请号：US11690700
申请日：2007-03-23
IPC分类号： A61N1/05
CPC分类号： A61N1/36521 , A61B5/0031 , A61B5/053 , A61B5/0538 , A61B5/11 , A61B5/686 , A61B5/6869 , A61N1/3627 , A61N1/3684
摘要： An apparatus comprises a first impedance sensing circuit, a second sensing circuit, and an impedance-based cardiac dyssynchrony detector. The impedance sensing circuit senses an intracardiac local impedance signal that is indicative of a cardiac local wall motion of a first cardiac region from an implantable first bipolar pair of impedance sensing electrodes. The second sensing circuit is configured to produce a second sensor signal indicative of cardiovascular activity. The impedance-based cardiac dyssynchrony detector is configured for detecting cardiac dyssynchrony using a relationship between the first intracardiac local impedance signal and the second sensor signal. Other apparatuses and methods are disclosed.
摘要翻译： 一种装置包括第一阻抗感测电路，第二感测电路和基于阻抗的心脏不同步检测器。 阻抗感测电路感测指示来自可植入的第一双极对阻抗感测电极的第一心脏区域的心脏局部壁运动的心内局部阻抗信号。 第二感测电路被配置为产生指示心血管活动的第二传感器信号。 基于阻抗的心脏不同步检测器被配置为使用第一心内局部阻抗信号和第二传感器信号之间的关系来检测心脏不同步。 公开了其他装置和方法。
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公开(公告)号：US20090157090A1
公开(公告)日：2009-06-18
申请号：US12236838
申请日：2008-09-24
CPC分类号： A61N1/056 , A61N1/36514
摘要： Systems and methods facilitate placement of a lead in or on a patient's heart. At least one reference sensor is positioned at a right heart location of a patient's heart and a cardiac lead apparatus comprising at least one lead apparatus sensor is advanced to a plurality of left heart locations. Using the reference sensor and the lead apparatus sensor, a distance parameter indicative of a distance between the reference and lead apparatus sensors is measured for each of the plurality of left heart locations. Strain or stress estimates are determined for the plurality of left heart locations derived from the distance parameter measurements. Using the strain or stress estimates, a physician perceivable output is produced indicating suitability of the left heart locations as pacing sites.
摘要翻译： 系统和方法有利于将铅放置在患者心脏中或患者的心脏上。 至少一个参考传感器位于患者心脏的右心脏位置，并且将包括至少一个引导装置传感器的心脏引导装置提前到多个左心脏位置。 使用参考传感器和引导装置传感器，针对多个左心脏位置中的每一个测量指示参考和引导装置传感器之间的距离的距离参数。 对于从距离参数测量导出的多个左心脏位置确定应变或应力估计。 使用应变或压力估计，产生医生可感知的输出，指示左心脏位置作为起搏部位的适合性。
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公开(公告)号：US09149631B2
公开(公告)日：2015-10-06
申请号：US12236838
申请日：2008-09-24
CPC分类号： A61N1/056 , A61N1/36514
摘要： Systems and methods facilitate placement of a lead in or on a patient's heart. At least one reference sensor is positioned at a right heart location of a patient's heart and a cardiac lead apparatus comprising at least one lead apparatus sensor is advanced to a plurality of left heart locations. Using the reference sensor and the lead apparatus sensor, a distance parameter indicative of a distance between the reference and lead apparatus sensors is measured for each of the plurality of left heart locations. Strain or stress estimates are determined for the plurality of left heart locations derived from the distance parameter measurements. Using the strain or stress estimates, a physician perceivable output is produced indicating suitability of the left heart locations as pacing sites.
摘要翻译： 系统和方法有利于将铅放置在患者心脏中或患者的心脏上。 至少一个参考传感器位于患者心脏的右心脏位置，并且包括至少一个引导装置传感器的心脏引导装置前进到多个左心脏位置。 使用参考传感器和引导装置传感器，针对多个左心脏位置中的每一个测量指示参考和引导装置传感器之间的距离的距离参数。 对于从距离参数测量导出的多个左心脏位置确定应变或应力估计。 使用应变或压力估计，产生医生可感知的输出，指示左心脏位置作为起搏部位的适合性。
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公开(公告)号：US07840267B2
公开(公告)日：2010-11-23
申请号：US11690700
申请日：2007-03-23
IPC分类号： A61N1/368
CPC分类号： A61N1/36521 , A61B5/0031 , A61B5/053 , A61B5/0538 , A61B5/11 , A61B5/686 , A61B5/6869 , A61N1/3627 , A61N1/3684
摘要： An apparatus comprises a first impedance sensing circuit, a second sensing circuit, and an impedance-based cardiac dyssynchrony detector. The impedance sensing circuit senses an intracardiac local impedance signal that is indicative of a cardiac local wall motion of a first cardiac region from an implantable first bipolar pair of impedance sensing electrodes. The second sensing circuit is configured to produce a second sensor signal indicative of cardiovascular activity. The impedance-based cardiac dyssynchrony detector is configured for detecting cardiac dyssynchrony using a relationship between the first intracardiac local impedance signal and the second sensor signal. Other apparatuses and methods are disclosed.
摘要翻译： 一种装置包括第一阻抗感测电路，第二感测电路和基于阻抗的心脏不同步检测器。 阻抗感测电路感测指示来自可植入的第一双极对阻抗感测电极的第一心脏区域的心脏局部壁运动的心内局部阻抗信号。 第二感测电路被配置为产生指示心血管活动的第二传感器信号。 基于阻抗的心脏不同步检测器被配置为使用第一心内局部阻抗信号和第二传感器信号之间的关系来检测心脏不同步。 公开了其他装置和方法。
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9.发明授权公开(公告)号：US08694129B2
公开(公告)日：2014-04-08
申请号：US12686050
申请日：2010-01-12
申请人： Dan Li , Allan C. Shuros , Andrea Acuna , Bruce A. Tockman
发明人： Dan Li , Allan C. Shuros , Andrea Acuna , Bruce A. Tockman
IPC分类号： A61B5/02
CPC分类号： A61N1/056 , A61B5/042 , A61B5/6846 , A61B5/6852 , A61M25/0082 , A61M25/01 , A61M25/0102 , A61M25/0662 , A61M2025/0681 , A61N1/37211 , A61N2001/0585
摘要： Systems and methods for deploying a sensor assembly onto a cardiac lead are disclosed. The sensor assembly can include a resilient cuff having one or more sensor modules for sensing physiological parameters within the body. The resilient cuff may have a substantially cylindrical shape having an inner diameter that is smaller than an outer diameter of the lead body onto which the cuff is deployed such that the cuff is retained on the lead body by frictional forces. The sensor assembly may be deployed in conjunction with a new lead to be implanted within a chamber of the patient's heart or a body vessel, or may be deployed onto an existing, implanted lead implanted within the patient's body.
摘要翻译： 公开了将传感器组件部署到心脏引线上的系统和方法。 传感器组件可以包括具有用于感测身体内的生理参数的一个或多个传感器模块的弹性袖带。 弹性箍可以具有基本上圆柱形的形状，其内径小于引导体的外径，袖带在其上展开，使得袖带通过摩擦力保持在引线体上。 传感器组件可以与将要植入患者心脏或身体容器的腔室内的新导线一起部署，或者可以部署到植入患者体内的现有植入的导线上。
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公开(公告)号：US20080281367A1
公开(公告)日：2008-11-13
申请号：US11745016
申请日：2007-05-07
申请人： Yi Zhang , Allan C. Shuros , Dan Li
发明人： Yi Zhang , Allan C. Shuros , Dan Li
IPC分类号： A61N1/362
CPC分类号： A61N1/36521 , A61B5/02028 , A61B5/0464 , A61B5/0535 , A61B5/0538 , A61B5/7264
摘要： An implantable medical device detects a tachyarrhythmia of a heart. During the detected tachyarrhythmia, the device determines a local myocardial impedance. Using the local myocardial impedance, the device determines whether there is sufficient perfusion to the heart. The device can then either deliver a less aggressive device therapy in response to the detected tachyarrhythmia when there is sufficient perfusion to the heart, or deliver a more aggressive device therapy in response to the detected tachyarrhythmia when there is insufficient perfusion to the heart. The perfusion information can also be used to alter tachyarrhythmia detection or classification.
摘要翻译： 可植入医疗装置检测心脏的快速性心律失常。 在检测到的快速性心律失常期间，该装置确定局部心肌阻抗。 使用局部心肌阻抗，该装置确定心脏是否有足够的灌注。 然后，当心脏充分灌注时，该装置可以响应于检测到的快速性心律失常而递送较不激进的装置疗法，或者当心脏灌注不充分时响应于检测到的快速性心律失常而递送更积极的装置疗法。 灌注信息也可用于改变快速性心律失常检测或分类。
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