公开(公告)号：US20210238672A1

公开(公告)日：2021-08-05

申请号：US17238090

申请日：2021-04-22

Applicant: Quantum Biosystems Inc.

Inventor： Eric S. NORDMAN ,  Valentin DIMITROV ,  Gaurav GOYAL ,  Jessica KILLIAN ,  Kazusuke MIHARA

IPC: C12Q1/6869 ,  C12Q1/00 ,  C12Q1/48

Abstract: The present disclosure provides methods and systems for detecting or analyzing a biomolecule. The methods and systems may comprise the use of a plurality of electrodes and a solution which may comprise a variety of reagents. In an example, the solution may comprise one or more redox-active molecules or compounds which may undergo or facilitate a redox cycling process. The redox cycling process may generate an electric signal that may be measured by one or more of the plurality of electrodes. An introduction of a nucleotide having a redox cycling current modifying particle coupled thereto to the solution may result in a change in the electric signal. The change in the electric signal may be used to identify the biomolecule or a portion thereof.