公开(公告)号：US11981966B2

公开(公告)日：2024-05-14

申请号：US16870033

申请日：2020-05-08

Applicant: Quest Diagnostics Investments LLC

Inventor： Heather Sanders ,  Kevin Qu ,  James Prentice ,  Frederic Waldman

IPC: C12Q1/6886

CPC classification number: C12Q1/6886 ,  C12Q2600/106 ,  C12Q2600/156 ,  C12Q2600/16

Abstract: The present technology relates to methods for determining whether a patient diagnosed with breast cancer, colorectal cancer, melanoma or lung cancer will benefit from or is predicted to be responsive to treatment with an individual therapeutic agent or a specific combination of therapeutic agents. These methods are based on screening a patient's solid tumors and detecting alterations in target nucleic acid sequences corresponding to a specific set of cancer-related genes. Kits for use in practicing the methods are also provided.