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    Method and system for detecting biological molecules in samples
    1.
    发明授权
    Method and system for detecting biological molecules in samples 有权
    检测样品中生物分子的方法和系统

    公开(公告)号：US09097672B2

    公开(公告)日：2015-08-04

    申请号：US13704719

    申请日：2011-06-17

    申请人： R. Stephen Brown ,  Eric Marcotte ,  Doug Wilton ,  Peter Gallant ,  David Dolphin ,  Lee Underwood

    发明人： R. Stephen Brown ,  Eric Marcotte ,  Doug Wilton ,  Peter Gallant ,  David Dolphin ,  Lee Underwood

    IPC分类号： G01N21/64 ,  G01N33/12 ,  G01N33/18 ,  B01L3/00

    CPC分类号： G01N21/6486 ,  B01L3/50825 ,  G01N21/6428 ,  G01N21/6452 ,  G01N33/12 ,  G01N33/1826 ,  G01N2021/6417 ,  G01N2021/6482 ,  G01N2021/6484 ,  G01N2201/062

    摘要： A system for detecting presence of an organism having an enzyme in a sample, comprising: a cartridge for containing the sample and a substrate such that the enzyme can react with the substrate to produce a biological molecule; a partitioning element mounted in a recess in a base of the cartridge, the partitioning element allowing partitioning of the biological molecule thereinto; a light source for irradiating the biological molecule partitioned into the partitioning element; and, a detector for detecting fluorescence of the biological molecule partitioned into the partitioning element, the detected fluorescence being indicative of presence of the organism in the sample; wherein the light source is in a raised cartridge mount of the system that mates with the recess in the base of the cartridge.

    摘要翻译： 一种用于检测样品中具有酶的生物体的存在的系统，包括：用于容纳样品和底物的筒，使得酶可以与底物反应以产生生物分子; 安装在所述盒的基部中的凹部中的分隔元件，所述分隔元件允许生物分子在其中分配; 用于照射被划分成分隔元件的生物分子的光源; 以及检测器，用于检测划分成分隔元件的生物分子的荧光，检测到的荧光指示样品中生物体的存在; 其中所述光源位于所述系统的凸起的盒安装件中，以与所述盒的所述底座中的凹部配合。

    METHOD AND SYSTEM FOR DETECTING BIOLOGICAL MOLECULES IN SAMPLES
    6.
    发明申请
    METHOD AND SYSTEM FOR DETECTING BIOLOGICAL MOLECULES IN SAMPLES 有权
    用于检测样品中生物分子的方法和系统

    公开(公告)号：US20130217040A1

    公开(公告)日：2013-08-22

    申请号：US13704719

    申请日：2011-06-17

    申请人： R. Stephen Brown ,  Eric Marcotte ,  Doug Wilton ,  Peter Gallant ,  David Dolphin ,  Lee Underwood

    发明人： R. Stephen Brown ,  Eric Marcotte ,  Doug Wilton ,  Peter Gallant ,  David Dolphin ,  Lee Underwood

    IPC分类号： G01N21/64

    CPC分类号： G01N21/6486 ,  B01L3/50825 ,  G01N21/6428 ,  G01N21/6452 ,  G01N33/12 ,  G01N33/1826 ,  G01N2021/6417 ,  G01N2021/6482 ,  G01N2021/6484 ,  G01N2201/062

    摘要： A system for detecting presence of an organism having an enzyme in a sample, comprising: a cartridge for containing the sample and a substrate such that the enzyme can react with the substrate to produce a biological molecule; a partitioning element mounted in a recess in a base of the cartridge, the partitioning element allowing partitioning of the biological molecule thereinto; a light source for irradiating the biological molecule partitioned into the partitioning element; and, a detector for detecting fluorescence of the biological molecule partitioned into the partitioning element, the detected fluorescence being indicative of presence of the organism in the sample; wherein the light source is in a raised cartridge mount of the system that mates with the recess in the base of the cartridge.

    摘要翻译： 一种用于检测样品中具有酶的生物体的存在的系统，包括：用于容纳样品和底物的筒，使得酶可以与底物反应以产生生物分子; 安装在所述盒的基部中的凹部中的分隔元件，所述分隔元件允许生物分子在其中分配; 用于照射被划分成分隔元件的生物分子的光源; 以及检测器，用于检测划分成分隔元件的生物分子的荧光，检测到的荧光指示样品中生物体的存在; 其中所述光源位于所述系统的凸起的盒安装件中，以与所述盒的所述底座中的凹部配合。

    Drug delivery systems for photodynamic therapy
    10.
    发明授权
    Drug delivery systems for photodynamic therapy 有权
    用于光动力治疗的药物输送系统

    公开(公告)号：US06693093B2

    公开(公告)日：2004-02-17

    申请号：US09851641

    申请日：2001-05-08

    申请人： Rubinah K. Chowdhary ,  David Dolphin

    发明人： Rubinah K. Chowdhary ,  David Dolphin

    IPC分类号： A61K3100

    CPC分类号： A61K9/0009 ,  A61K9/0019 ,  A61K9/10 ,  A61K9/1278 ,  A61K31/409 ,  A61K31/555 ,  A61K31/787 ,  A61K41/00 ,  A61K41/0057 ,  A61K41/0071

    摘要： The invention is generally related to the field of photodynamic therapy by use of photosensitizers and stabilized formulations of the photosensitizers. These formulations may be used to deliver a photosensitizer as a pharmaceutical, agricultural, or industrial agent. The photosensitizer containing formulations and compositions of the invention comprise one or more block copolymers. Furthermore, the invention relates to processes for the production of, and application of, said formulations and compositions as photosensitizer drug delivery systems.

    摘要翻译： 本发明通常通过使用光敏剂和光敏剂的稳定配方与光动力疗法领域相关。 这些制剂可用于递送光敏剂作为药物，农业或工业剂。 含有本发明制剂和组合物的光敏剂包含一种或多种嵌段共聚物。 此外，本发明涉及用于制备和应用所述制剂和组合物作为光敏药物递送系统的方法。