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公开(公告)号：US10226534B2
公开(公告)日：2019-03-12
申请号：US15021573
申请日：2014-09-12
发明人： Wenshou Wang , Chun Wang
IPC分类号： A61K47/34 , A61K9/06 , A61K38/38 , C08G65/331 , A61K9/51 , C08G63/664 , C08G81/00 , C08L71/02 , A61K9/00
摘要： The invention provides semi-solid systems for delivering biologically active materials that include a polymer comprising 1) one or more polycaprolactone (PCL) units and 2) at least one or more polyethylene glycol (PEG) units; wherein at least one of said polycaprolactone units is conjugated to a PEG forming an acetal group.
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公开(公告)号：US10179173B2
公开(公告)日：2019-01-15
申请号：US14387178
申请日：2013-03-12
发明人： Chun Wang , Wenshou Wang , John R. Ohlfest
IPC分类号： A61K47/34 , C08G63/664 , A61K9/51 , A61K9/00 , A61K9/14 , A61K31/192 , A61K31/437 , A61K38/38 , A61K39/00 , C08G65/332
摘要： The invention provides semi-solid systems for delivering biologically active materials that include a polymer comprising 1) one or more units of formula Ia, IIa, or IIIa: (formula Ia, IIa, IIIa) and 2) one or more units comprising polycaprolactone; wherein R and Ra have any of the values defined in the application.
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公开(公告)号：US20150283244A1
公开(公告)日：2015-10-08
申请号：US14387178
申请日：2013-03-12
发明人： Chun Wang , Wenshou Wang , John R. Ohlfest
IPC分类号： A61K47/34 , C08G65/332 , A61K39/00 , C08G63/664 , A61K31/192 , A61K38/38
CPC分类号： A61K47/34 , A61K9/0019 , A61K9/0024 , A61K9/5153 , A61K31/192 , A61K31/437 , A61K38/385 , A61K39/0005 , C08G63/664 , C08G65/3322
摘要： The invention provides semi-solid systems for delivering biologically active materials that include a polymer comprising 1) one or more units of formula Ia, IIa, or IIIa: (formula Ia, IIa, IIIa) and 2) one or more units comprising polycaprolactone; wherein R and Ra have any of the values defined in the application.
摘要翻译： 本发明提供用于递送生物活性材料的半固体系统，其包括聚合物，其包含1）一种或多种式Ia，IIa或IIIa单元：（式Ia，IIa，IIIa）和2）一种或多种包含聚己内酯的单元; 其中R和R a具有在本申请中定义的任何值。
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