公开(公告)号：US10822318B2

公开(公告)日：2020-11-03

申请号：US15988986

申请日：2018-05-24

申请人： REGENTS OF THE UNIVERSITY OF MINNESOTA ,  Indiana University Research and Technology Corporation

发明人： Erin Elizabeth Carlson ,  Shabnam Sharifzadeh ,  Alireza Shokri ,  Ozden Kocaoglu ,  Clayton L. Brown, Jr.

IPC分类号： C07D305/12 ,  C07D407/12 ,  G01N33/68 ,  G07F5/02 ,  C07D405/12 ,  G01N33/58 ,  G01N33/573 ,  C07F5/02

摘要： The invention provides a compound of formula I: or a salt thereof, wherein R1, R2, R3, R4, L1, L2 and Y have any of the values described in the specification, as well as compositions comprising a compound of formula I. The compounds are useful for labeling penicillin-binding proteins (PBPs).

公开(公告)号：US20180339972A1

公开(公告)日：2018-11-29

申请号：US15988986

申请日：2018-05-24

申请人： REGENTS OF THE UNIVERSITY OF MINNESOTA ,  Indiana University Research and Technology Corporation

发明人： Erin Elizabeth Carlson ,  Shabnam Sharifzadeh ,  Alireza Shokri ,  Ozden Kocaoglu ,  Clayton Brown

IPC分类号： C07D305/12 ,  C07D407/12 ,  C07D405/12 ,  C07F5/02 ,  G01N33/68

CPC分类号： C07D305/12 ,  C07D405/12 ,  C07D407/12 ,  C07F5/022 ,  G01N33/573 ,  G01N33/582 ,  G01N33/68 ,  G01N2333/948 ,  G01N2415/00

摘要： The invention provides a compound of formula I: or a salt thereof, wherein R1, R2, R3, R4, L1, L2 and Y have any of the values described in the specification, as well as compositions comprising a compound of formula I. The compounds are useful for labeling penicillin-binding proteins (PBPs).

公开(公告)号：US20180292387A1

公开(公告)日：2018-10-11

申请号：US15947302

申请日：2018-04-06

申请人： REGENTS OF THE UNIVERSITY OF MINNESOTA

发明人： Erin Elizabeth Carlson ,  Shabnam Sharifzadeh

IPC分类号： G01N33/50 ,  A61K47/55 ,  A61K47/22 ,  A61K31/397 ,  A61P31/04

摘要： The invention provides a conjugate of formula I: R-L-Y   I or a salt thereof, wherein R, L, and Y have any of the values described in the specification, as well as compositions comprising a conjugate of formula I. The conjugates are useful for labeling.

公开(公告)号：US11022602B2

公开(公告)日：2021-06-01

申请号：US15947302

申请日：2018-04-06

申请人： REGENTS OF THE UNIVERSITY OF MINNESOTA

发明人： Erin Elizabeth Carlson ,  Shabnam Sharifzadeh

IPC分类号： C07D477/00 ,  C07D501/20 ,  G01N33/50 ,  A61K47/55 ,  A61K47/22 ,  A61P31/04 ,  A61K31/397 ,  A61K49/00 ,  G01N33/58 ,  G01N33/566 ,  G01N33/532 ,  A61K47/12 ,  A61K47/16

摘要： The invention provides a conjugate of formula I: R-L-Y   I or a salt thereof, wherein R, L, and Y have any of the values described in the specification, as well as compositions comprising a conjugate of formula I. The conjugates are useful for labeling.