公开(公告)号：US09320802B2

公开(公告)日：2016-04-26

申请号：US14683579

申请日：2015-04-10

Applicant: ROHTO PHARMACEUTICAL CO., LTD.

Inventor： Chinatsu Furumiya ,  Takayuki Miyano ,  Atsuko Nakata ,  Eri Matsumoto

IPC: A61K47/10 ,  A61K47/44 ,  A61K9/08 ,  A61K9/00 ,  A61K47/02 ,  A61K47/26 ,  A61K47/24

CPC classification number: A61K47/44 ,  A61K9/0048 ,  A61K9/08 ,  A61K47/02 ,  A61K47/10 ,  A61K47/24 ,  A61K47/26

Abstract: This invention relates to an aqueous ophthalmic composition comprising (A) polyoxyethylene castor oil in which the average number of moles of added ethylene oxide is 2 to 12 and (B) terpenoid. According to the present invention, an aqueous ophthalmic composition having an improved foam disappearance speed can be obtained.

公开(公告)号：US09345779B2

公开(公告)日：2016-05-24

申请号：US14634270

申请日：2015-02-27

Applicant: ROHTO PHARMACEUTICAL CO., LTD.

Inventor： Atsuko Nakata ,  Eri Matsumoto

IPC: A61K47/46 ,  A61K47/44 ,  A61K9/00 ,  A61K47/02

CPC classification number: A61K47/46 ,  A61K9/0048 ,  A61K47/02 ,  A61K47/44

Abstract: This invention relates to an aqueous ophthalmic composition comprising (A) polyoxyethylene castor oil and (B) sesame oil. According to the aqueous ophthalmic composition of the present invention, defoaming time is reduced, preservative efficacy is enhanced and photostability is improved.

公开(公告)号：US09050369B2

公开(公告)日：2015-06-09

申请号：US13720734

申请日：2012-12-19

Applicant: ROHTO PHARMACEUTICAL CO., LTD.

Inventor： Atsuko Nakata ,  Eri Matsumoto

IPC: A61K47/44 ,  A61K9/00

CPC classification number: A61K47/46 ,  A61K9/0048 ,  A61K47/02 ,  A61K47/44

Abstract: This invention relates to an aqueous ophthalmic composition comprising (A) polyoxyethylene castor oil and (B) sesame oil. According to the aqueous ophthalmic composition of the present invention, defoaming time is reduced, preservative efficacy is enhanced and photostability is improved.

Abstract translation: 本发明涉及含有（A）聚氧乙烯蓖麻油和（B）芝麻油的水性眼用组合物。 根据本发明的水性眼用组合物，消泡时间降低，防腐效果提高，光稳定性提高。