公开(公告)号：US08754029B2

公开(公告)日：2014-06-17

申请号：US13678064

申请日：2012-11-15

Applicant: Rohto Pharmaceutical Co., Ltd.

Inventor： Yasuko Matsumura ,  Kazuhiro Fukushima

IPC: A61K31/00

CPC classification number: A61K31/045 ,  A61F9/0061 ,  A61K9/0046 ,  A61K31/125 ,  A61K31/717 ,  A61K31/721 ,  A61K31/74

Abstract: The present invention provides an ophthalmic composition which stabilizes the tear film during wearing contact lens, prevents eye dryness, imparts a favorable sensation in using, is highly convenient with no risk of misuse and shows a high efficiency in the course from manufacturing to sales. More specifically, the present invention provides a wetting solution—eye drops for contact lenses comprising (A) one or more member(s) selected from the group consisting of a cellulose-based polymer, a vinyl-based polymer, polyethylene glycol and dextran; and (B) a terpenoid.

Abstract translation: 本发明提供了一种眼用组合物，其在佩戴隐形眼镜期间稳定了泪膜，防止眼睛干涩，赋予使用感觉，非常方便，没有被误用的风险，并且在制造过程中显示出高效率。 更具体地说，本发明提供一种用于隐形眼镜的润湿溶液 - 滴眼剂，其包括（A）一种或多种选自纤维素基聚合物，乙烯基类聚合物，聚乙二醇和葡聚糖的成员; 和（B）萜类化合物。

公开(公告)号：US20150064281A1

公开(公告)日：2015-03-05

申请号：US14391559

申请日：2013-04-04

Applicant: ROHTO PHARMACEUTICAL CO., LTD.

Inventor： Kazuhiro Fukushima ,  Mariyo Kato ,  Yoshihiro Takai ,  Masashi Itoh

IPC: A61K31/155 ,  A61K33/30

CPC classification number: A61K31/155 ,  A61K31/785 ,  A61K33/22 ,  A61K33/30 ,  A61L12/142 ,  A61K2300/00

Abstract: The present invention provides an ophthalmic composition containing (A) a biguanide-based disinfectant and (B) zinc chloride. According to the present invention, an ophthalmic composition having remarkably increased disinfection effects against Acanthamoeba is provided.

Abstract translation: 本发明提供含有（A）双胍类消毒剂和（B）氯化锌的眼用组合物。 根据本发明，提供了对棘阿米巴具有显着提高的消毒效果的眼用组合物。