-
公开(公告)号:US09173945B2
公开(公告)日:2015-11-03
申请号:US14355350
申请日:2012-10-31
IPC分类号: A61F2/00 , A61K47/38 , A61K9/08 , A61K31/045 , A61K31/122 , A61K31/125 , A61K33/30 , A61K9/00 , A61K47/10 , A61K47/32 , A61K47/36
CPC分类号: A61K47/38 , A61K9/0048 , A61K9/08 , A61K31/045 , A61K31/122 , A61K31/125 , A61K33/30 , A61K47/10 , A61K47/32 , A61K47/36 , A61K2300/00
摘要: The present invention provides an aqueous ophthalmic composition containing (A) a terpenoid, (B) zinc chloride, and (C) at least one member selected from the group consisting of cellulose-based polymeric compounds, vinyl-based polymeric compounds, polyethylene glycols and dextran. According to the present invention, an aqueous ophthalmic composition is provided in which adsorption of the terpenoid to a container can be inhibited, thereby making it possible to inhibit the reduction in the terpenoid content for a long period of time, the aqueous ophthalmic composition having some excellent actions such as an inhibitory action for histamine release, and an inhibitory action for discharges from the eyes.
摘要翻译: 本发明提供含有(A)萜类化合物,(B)氯化锌和(C)至少一种选自纤维素基聚合物,乙烯基类聚合物,聚乙二醇和 葡聚糖 根据本发明,提供一种眼科组合物,其中可以抑制萜类化合物对容器的吸附,从而可以长时间抑制萜类化合物含量的降低,眼用组合物具有一些 优良的作用如对组胺释放的抑制作用,以及从眼睛排出的抑制作用。
-
公开(公告)号:US20140308368A1
公开(公告)日:2014-10-16
申请号:US14355350
申请日:2012-10-31
IPC分类号: A61K47/38 , A61K31/122 , A61K47/36 , A61K33/30 , A61K47/32 , A61K47/10 , A61K31/045 , A61K31/125
CPC分类号: A61K47/38 , A61K9/0048 , A61K9/08 , A61K31/045 , A61K31/122 , A61K31/125 , A61K33/30 , A61K47/10 , A61K47/32 , A61K47/36 , A61K2300/00
摘要: The present invention provides an aqueous ophthalmic composition containing (A) a terpenoid, (B) zinc chloride, and (C) at least one member selected from the group consisting of cellulose-based polymeric compounds, vinyl-based polymeric compounds, polyethylene glycols and dextran. According to the present invention, an aqueous ophthalmic composition is provided in which adsorption of the terpenoid to a container can be inhibited, thereby making it possible to inhibit the reduction in the terpenoid content for a long period of time, the aqueous ophthalmic composition having some excellent actions such as an inhibitory action for histamine release, and an inhibitory action for discharges from the eyes.
摘要翻译: 本发明提供含有(A)萜类化合物,(B)氯化锌和(C)至少一种选自纤维素基聚合物,乙烯基类聚合物,聚乙二醇和 葡聚糖 根据本发明,提供一种眼科组合物,其中可以抑制萜类化合物对容器的吸附,从而可以长时间抑制萜类化合物含量的降低,眼用组合物具有一些 优良的作用如对组胺释放的抑制作用,以及从眼睛排出的抑制作用。
-
公开(公告)号:US20170105934A1
公开(公告)日:2017-04-20
申请号:US15317851
申请日:2015-06-09
发明人: Yoko Mizutare , Yasuko Matsumura
摘要: An aqueous ophthalmic composition is provided comprising at least one component which is selected from the group consisting of a polysaccharide, a monosaccharide, at least one vitamin component selected from the group consisting of vitamin B12, vitamin B2, vitamin A and panthenol, at least one oil component selected from the group consisting of a plant oil, an animal oil and a mineral oil, at least one surfactant selected from the group consisting of polyoxyethylene castor oil, polyoxyethylene hydrogenated castor oil, polyoxyethylene polyoxypropylene glycol and polyoxyl stearate, an anti-allergic component, a preservative, a thickening component, a polyhydric alcohol, an anti-inflammatory component, an anti-bacterial agent and a cooling and/or refreshing agent; and (B) a buffering agent. When the composition is brought into contact with a polybutylene terephthalate-containing resin container, the container can be prevented from weight change, deterioration and wetting and can be improved in a liquid cutting property.
-
公开(公告)号:US20140296348A1
公开(公告)日:2014-10-02
申请号:US14355383
申请日:2012-10-31
IPC分类号: A61K47/02 , A61K31/045
CPC分类号: A61K47/02 , A61K9/0048 , A61K9/08 , A61K31/045 , A61K31/122 , A61K31/125 , A61K33/30 , A61K2300/00
摘要: The present invention provides an aqueous ophthalmic composition having a pH of 7 or more, containing a terpenoid and zinc chloride. According to the present invention, an aqueous ophthalmic composition is provided in which adsorption of the terpenoid to a container can be inhibited, thereby making it possible to inhibit the reduction in the terpenoid content for a long period of time, the aqueous ophthalmic composition having some excellent actions such as an inhibitory action for histamine release, and an inhibitory action for discharges from the eyes.
摘要翻译: 本发明提供了含有萜类化合物和氯化锌的pH为7以上的水性眼用组合物。 根据本发明,提供一种眼科组合物,其中可以抑制萜类化合物对容器的吸附,从而可以长时间抑制萜类化合物含量的降低,眼用组合物具有一些 优良的作用如对组胺释放的抑制作用,以及从眼睛排出的抑制作用。
-
公开(公告)号:US08754029B2
公开(公告)日:2014-06-17
申请号:US13678064
申请日:2012-11-15
IPC分类号: A61K31/00
CPC分类号: A61K31/045 , A61F9/0061 , A61K9/0046 , A61K31/125 , A61K31/717 , A61K31/721 , A61K31/74
摘要: The present invention provides an ophthalmic composition which stabilizes the tear film during wearing contact lens, prevents eye dryness, imparts a favorable sensation in using, is highly convenient with no risk of misuse and shows a high efficiency in the course from manufacturing to sales. More specifically, the present invention provides a wetting solution—eye drops for contact lenses comprising (A) one or more member(s) selected from the group consisting of a cellulose-based polymer, a vinyl-based polymer, polyethylene glycol and dextran; and (B) a terpenoid.
摘要翻译: 本发明提供了一种眼用组合物,其在佩戴隐形眼镜期间稳定了泪膜,防止眼睛干涩,赋予使用感觉,非常方便,没有被误用的风险,并且在制造过程中显示出高效率。 更具体地说,本发明提供一种用于隐形眼镜的润湿溶液 - 滴眼剂,其包括(A)一种或多种选自纤维素基聚合物,乙烯基类聚合物,聚乙二醇和葡聚糖的成员; 和(B)萜类化合物。
-
公开(公告)号:US20180161438A1
公开(公告)日:2018-06-14
申请号:US15577560
申请日:2016-05-24
发明人: Yasuko Matsumura
IPC分类号: A61K47/44 , A61K9/08 , A61K9/00 , A61K9/06 , A61K47/32 , A61K47/38 , A61K47/02 , A61K47/10 , A61K47/36 , A61K47/18 , A61K47/22 , A61K31/27 , A61K31/4164 , A61K31/4174 , A61K31/635 , A61K47/34 , A61K47/26 , A61K47/20 , A61K47/12
CPC分类号: A61K47/44 , A61K9/0048 , A61K9/06 , A61K9/08 , A61K31/27 , A61K31/4164 , A61K31/4174 , A61K31/635 , A61K47/02 , A61K47/10 , A61K47/12 , A61K47/18 , A61K47/186 , A61K47/20 , A61K47/22 , A61K47/26 , A61K47/32 , A61K47/34 , A61K47/36 , A61K47/38
摘要: The present invention relates to an aqueous ophthalmic composition that contains (A) vaseline and (B) at least one selected from the group consisting of a vinyl-based polymer compound, a saccharide, an amino acid, polyalcohol, a preservative, a sulfa drug, a vitamin, an inorganic salt compound, an ocular muscle modulator component, a vasoconstrictor, a stabilizer, polyoxyethylene polyoxypropylene glycol, and a vegetable oil.
-
公开(公告)号:US11331390B2
公开(公告)日:2022-05-17
申请号:US16094919
申请日:2017-04-21
发明人: Yasuko Matsumura
IPC分类号: A61K47/26 , A61K9/00 , A61K31/045 , A61K31/14 , A61K31/355 , A61K47/44 , A61K47/10 , C08J5/00 , A61K47/18 , A61K47/12 , A61K47/02 , A61K47/22
摘要: The first aspect of the present invention relates to an ophthalmic composition comprising (A) one or more kinds selected from the group consisting of terpenoid, a tocopherol, and a benzyl ammonium compound and a salt thereof, wherein the ophthalmic composition is contained in a container in which a portion or the whole of a part coming into contact with the ophthalmic composition is formed from a resin containing a cyclic olefin.
The second aspect of the present invention relates to an ophthalmic composition comprising (A2) a surface active component and (B2) a buffer, wherein the ophthalmic composition is contained in a container in which a portion or the whole of a part coming into contact with the ophthalmic composition is formed from a resin containing a cyclic olefin.-
公开(公告)号:US20190125877A1
公开(公告)日:2019-05-02
申请号:US16094919
申请日:2017-04-21
发明人: Yasuko Matsumura
IPC分类号: A61K47/26 , A61K9/00 , A61K31/045 , A61K31/14 , A61K31/355 , A61K47/44 , A61K47/10 , C08J5/00
摘要: The first aspect of the present invention relates to an ophthalmic composition comprising (A) one or more kinds selected from the group consisting of terpenoid, a tocopherol, and a benzyl ammonium compound and a salt thereof, wherein the ophthalmic composition is contained in a container in which a portion or the whole of a part coming into contact with the ophthalmic composition is formed from a resin containing a cyclic olefin.The second aspect of the present invention relates to an ophthalmic composition comprising (A2) a surface active component and (B2) a buffer, wherein the ophthalmic composition is contained in a container in which a portion or the whole of a part coming into contact with the ophthalmic composition is formed from a resin containing a cyclic olefin.
-
-
-
-
-
-
-