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公开(公告)号：US20170016076A1
公开(公告)日：2017-01-19
申请号：US15237364
申请日：2016-08-15
Applicant: ROSETTA GENOMICS, LTD.
Inventor： Zohar Barnett-Itzhaki , Gila Lithwick Yanai , Eti Meiri , Yael Spector , Hila Benjamin , Nir Dromi
CPC classification number: C12Q1/6886 , C12Q2600/112 , C12Q2600/158 , C12Q2600/178 , G06F19/18 , G06F19/20
Abstract: The present invention provides a method for classification of thyroid tumors through the analysis of the expression patterns of specific microRNAs in fine needle aspiration samples. Thyroid tumor classification according to a microRNA expression signature allows optimization of diagnosis and treatment, as well as determination of signature-specific therapy.
Abstract translation: 本发明提供了通过分析细针抽吸样品中特异性微小RNA的表达模式来分类甲状腺肿瘤的方法。 根据微小RNA表达特征的甲状腺肿瘤分类可以优化诊断和治疗，以及确定特异性特异性治疗。
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公开(公告)号：US09708667B2
公开(公告)日：2017-07-18
申请号：US15237364
申请日：2016-08-15
Applicant: ROSETTA GENOMICS, LTD.
Inventor： Gila Lithwick Yanai , Eti Meiri , Yael Spector , Hila Benjamin , Nir Dromi
CPC classification number: C12Q1/6886 , C12Q2600/112 , C12Q2600/158 , C12Q2600/178 , G06F19/18 , G06F19/20
Abstract: The present invention provides a method for classification of thyroid tumors through the analysis of the expression patterns of specific microRNAs in fine needle aspiration samples. Thyroid tumor classification according to a microRNA expression signature allows optimization of diagnosis and treatment, as well as determination of signature-specific therapy.
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Patent Agency Ranking
3.发明授权公开(公告)号：US09006206B2
公开(公告)日：2015-04-14
申请号：US14280822
申请日：2014-05-19
Inventor： Moshe Oren , Nina Raver-Shapira , Efi Marciano , Yael Spector
IPC: C12N15/11 , C07H21/02 , C07H21/04 , A61K48/00 , C12Q1/68 , A61K31/7105 , A61K45/06 , C12N15/113
CPC classification number: C12Q1/6886 , A61K31/7105 , A61K45/06 , C12N15/1135 , C12N2310/113 , C12N2310/141 , C12Q2600/158 , C12Q2600/178
Abstract: Described herein are compositions and methods for modulation of p53-dependent cell death and cell proliferation. The compositions are microRNAs and associated nucleic acids.
Abstract translation: 本文描述了调节p53依赖性细胞死亡和细胞增殖的组合物和方法。 组合物是微小RNA和相关核酸。
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公开(公告)号：US20140243230A1
公开(公告)日：2014-08-28
申请号：US14168981
申请日：2014-01-30
Inventor： Nitzan ROSENFELD , Yael Spector , Eddie Friedman , Zohar Dotan
IPC: C12Q1/68
CPC classification number: C12Q1/68 , C12Q1/6886 , C12Q2600/112 , C12Q2600/118 , C12Q2600/158 , C12Q2600/178
Abstract: The present invention provides a method for classification of kidney tumors through the analysis of the expression patterns of specific microRNAs and nucleic acid molecules relating thereto. Classification according to a microRNA expression framework allows optimization of treatment, and determination of specific therapy.
Abstract translation: 本发明提供了通过分析与其有关的特异性微小RNA和核酸分子的表达模式来分类肾肿瘤的方法。 根据microRNA表达框架进行分类可以优化治疗，并确定特异性治疗。
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公开(公告)号：US09340823B2
公开(公告)日：2016-05-17
申请号：US14168981
申请日：2014-01-30
Inventor： Nitzan Rosenfeld , Yael Spector , Eddie Friedman , Zohar Dotan
IPC: C12Q1/68
CPC classification number: C12Q1/68 , C12Q1/6886 , C12Q2600/112 , C12Q2600/118 , C12Q2600/158 , C12Q2600/178
Abstract: The present invention provides a method for classification of kidney tumors through the analysis of the expression patterns of specific microRNAs and nucleic acid molecules relating thereto. Classification according to a microRNA expression framework allows optimization of treatment, and determination of specific therapy.
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公开(公告)号：US20190300963A1
公开(公告)日：2019-10-03
申请号：US16192221
申请日：2018-11-15
Applicant: ROSETTA GENOMICS LTD.
Inventor： Zohar Barnett-Itzhaki , Gila Lithwick Yanai , Eti Meiri , Yael Spector , Hila Benjamin , Nir Dromi
IPC: C12Q1/6886 , G16B20/00 , G16B25/00
Abstract: The present invention provides a method for classification of thyroid tumors through the analysis of the expression patterns of specific microRNAs in fine needle aspiration samples. Thyroid tumor classification according to a microRNA expression signature allows optimization of diagnosis and treatment, as well as determination of signature-specific therapy.
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公开(公告)号：US20170356055A1
公开(公告)日：2017-12-14
申请号：US15625645
申请日：2017-06-16
Applicant: ROSETTA GENOMICS, LTD.
Inventor： Zohar Barnett-Itzhaki , Gila Lithwick Yanai , Eti Meiri , Yael Spector , Hila Benjamin , Nir Dromi
CPC classification number: C12Q1/6886 , C12Q2600/112 , C12Q2600/158 , C12Q2600/178 , G16B20/00 , G16B25/00
Abstract: The present invention provides a method for classification of thyroid tumors through the analysis of the expression patterns of specific microRNAs in fine needle aspiration samples. Thyroid tumor classification according to a microRNA expression signature allows optimization of diagnosis and treatment, as well as determination of signature-specific therapy.
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