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公开(公告)号：US09708667B2
公开(公告)日：2017-07-18
申请号：US15237364
申请日：2016-08-15
Applicant: ROSETTA GENOMICS, LTD.
Inventor： Gila Lithwick Yanai , Eti Meiri , Yael Spector , Hila Benjamin , Nir Dromi
CPC classification number: C12Q1/6886 , C12Q2600/112 , C12Q2600/158 , C12Q2600/178 , G06F19/18 , G06F19/20
Abstract: The present invention provides a method for classification of thyroid tumors through the analysis of the expression patterns of specific microRNAs in fine needle aspiration samples. Thyroid tumor classification according to a microRNA expression signature allows optimization of diagnosis and treatment, as well as determination of signature-specific therapy.
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公开(公告)号：US20170016076A1
公开(公告)日：2017-01-19
申请号：US15237364
申请日：2016-08-15
Applicant: ROSETTA GENOMICS, LTD.
Inventor： Zohar Barnett-Itzhaki , Gila Lithwick Yanai , Eti Meiri , Yael Spector , Hila Benjamin , Nir Dromi
CPC classification number: C12Q1/6886 , C12Q2600/112 , C12Q2600/158 , C12Q2600/178 , G06F19/18 , G06F19/20
Abstract: The present invention provides a method for classification of thyroid tumors through the analysis of the expression patterns of specific microRNAs in fine needle aspiration samples. Thyroid tumor classification according to a microRNA expression signature allows optimization of diagnosis and treatment, as well as determination of signature-specific therapy.
Abstract translation: 本发明提供了通过分析细针抽吸样品中特异性微小RNA的表达模式来分类甲状腺肿瘤的方法。 根据微小RNA表达特征的甲状腺肿瘤分类可以优化诊断和治疗，以及确定特异性特异性治疗。
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Patent Agency Ranking
公开(公告)号：US20190032142A1
公开(公告)日：2019-01-31
申请号：US15909145
申请日：2018-03-01
Applicant: Rosetta Genomics Ltd.
Inventor： Ranit Aharonov , Nitzan Rosenfeld , Shai Rosenwald , Nir Dromi
IPC: C12Q1/6886
Abstract: The present invention provides a process for classification of cancers and tissues of origin through the analysis of the expression patterns of specific microRNAs and nucleic acid molecules relating thereto. Classification according to a microRNA tree-based expression framework allows optimization of treatment, and determination of specific therapy.
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4.发明授权Gene expression signature for classification of tissue of origin of tumor samples 有权用于肿瘤样品来源组织分类的基因表达特征公开(公告)号：US09096906B2
公开(公告)日：2015-08-04
申请号：US13856190
申请日：2013-04-03
Applicant: Rosetta Genomics Ltd.
Inventor： Ranit Aharonov , Nitzan Rosenfeld , Shai Rosenwald , Nir Dromi
IPC: C12Q1/68
CPC classification number: C12Q1/6886 , C12Q2600/158 , C12Q2600/178
Abstract: The present invention provides a process for classification of cancers and tissues of origin through the analysis of the expression patterns of specific microRNAs and nucleic acid molecules relating thereto. Classification according to a microRNA tree-based expression framework allows optimization of treatment, and determination of specific therapy.
Abstract translation: 本发明通过分析与其有关的特异性微小RNA和核酸分子的表达模式，提供了对癌症和原始组织进行分类的方法。 根据基于microRNA树的表达框架进行分类可以优化治疗，并确定特异性治疗。
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5.发明申请METHODS AND MATERIALS FOR CLASSIFICATION OF TISSUE OF ORIGIN OF TUMOR SAMPLES 审中-公开用于分类肿瘤样品原始组织的方法和材料公开(公告)号：US20150368724A1
公开(公告)日：2015-12-24
申请号：US14746487
申请日：2015-06-22
Applicant: Rosetta Genomics Ltd.
Inventor： Ranit Aharonov , Nitzan Rosenfeld , Shai Rosenwald , Nir Dromi
IPC: C12Q1/68
CPC classification number: C12Q1/6886 , C12Q2600/158 , C12Q2600/178
Abstract: The present invention provides a process for classification of cancers and tissues of origin through the analysis of the expression patterns of specific microRNAs and nucleic acid molecules relating thereto. Classification according to a microRNA tree-based expression framework allows optimization of treatment, and determination of specific therapy.
Abstract translation: 本发明通过分析与其有关的特异性微小RNA和核酸分子的表达模式，提供了对癌症和原始组织进行分类的方法。 根据基于microRNA树的表达框架进行分类可以优化治疗，并确定特异性治疗。
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公开(公告)号：US20190300963A1
公开(公告)日：2019-10-03
申请号：US16192221
申请日：2018-11-15
Applicant: ROSETTA GENOMICS LTD.
Inventor： Zohar Barnett-Itzhaki , Gila Lithwick Yanai , Eti Meiri , Yael Spector , Hila Benjamin , Nir Dromi
IPC: C12Q1/6886 , G16B20/00 , G16B25/00
Abstract: The present invention provides a method for classification of thyroid tumors through the analysis of the expression patterns of specific microRNAs in fine needle aspiration samples. Thyroid tumor classification according to a microRNA expression signature allows optimization of diagnosis and treatment, as well as determination of signature-specific therapy.
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公开(公告)号：US20170356055A1
公开(公告)日：2017-12-14
申请号：US15625645
申请日：2017-06-16
Applicant: ROSETTA GENOMICS, LTD.
Inventor： Zohar Barnett-Itzhaki , Gila Lithwick Yanai , Eti Meiri , Yael Spector , Hila Benjamin , Nir Dromi
CPC classification number: C12Q1/6886 , C12Q2600/112 , C12Q2600/158 , C12Q2600/178 , G16B20/00 , G16B25/00
Abstract: The present invention provides a method for classification of thyroid tumors through the analysis of the expression patterns of specific microRNAs in fine needle aspiration samples. Thyroid tumor classification according to a microRNA expression signature allows optimization of diagnosis and treatment, as well as determination of signature-specific therapy.
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