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公开(公告)号：US20190241966A1
公开(公告)日：2019-08-08
申请号：US16226406
申请日：2018-12-19
Applicant: Rosetta Genomics Ltd.
Inventor： Ranit Aharonov , Nitzan Rosenfeld , Shai Rosenwald
IPC: C12Q1/6886
CPC classification number: C12Q1/6886 , C12Q2600/158 , C12Q2600/178
Abstract: The present invention provides a process for classification of cancers and tissues of origin through the analysis of the expression patterns of specific microRNAs and nucleic acid molecules relating thereto. Classification according to a microRNA tree-based expression framework allows optimization of treatment, and determination of specific therapy.
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2.发明授权公开(公告)号：US09243296B2
公开(公告)日：2016-01-26
申请号：US14446505
申请日：2014-07-30
Applicant: Rosetta Genomics Ltd.
Inventor： Ayelet Chajut , Shai Rosenwald
IPC: C07H21/04 , C12Q1/68 , C12N15/113
CPC classification number: C12Q1/6886 , C12N15/113 , C12N2310/113 , C12N2310/141 , C12N2310/315 , C12N2310/321 , C12N2310/346 , C12N2320/30 , C12Q2600/118 , C12Q2600/158 , C12Q2600/16 , C12Q2600/178 , C12N2310/3521
Abstract: Described herein are compositions and methods for prognosis and treatment of prostate cancer patients. Specifically the invention relates to microRNA molecules associated with the prognosis of prostate cancer, as well as various nucleic acid molecules relating thereto or derived therefrom.
Abstract translation: 本文描述了用于预后和治疗前列腺癌患者的组合物和方法。 具体地说，本发明涉及与前列腺癌的预后相关的微小RNA分子以及与之相关的或从其衍生的各种核酸分子。
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3.发明申请METHODS AND MATERIALS FOR CLASSIFICATION OF TISSUE OF ORIGIN OF TUMOR SAMPLES 审中-公开用于分类肿瘤样品原始组织的方法和材料公开(公告)号：US20150368724A1
公开(公告)日：2015-12-24
申请号：US14746487
申请日：2015-06-22
Applicant: Rosetta Genomics Ltd.
Inventor： Ranit Aharonov , Nitzan Rosenfeld , Shai Rosenwald , Nir Dromi
IPC: C12Q1/68
CPC classification number: C12Q1/6886 , C12Q2600/158 , C12Q2600/178
Abstract: The present invention provides a process for classification of cancers and tissues of origin through the analysis of the expression patterns of specific microRNAs and nucleic acid molecules relating thereto. Classification according to a microRNA tree-based expression framework allows optimization of treatment, and determination of specific therapy.
Abstract translation: 本发明通过分析与其有关的特异性微小RNA和核酸分子的表达模式，提供了对癌症和原始组织进行分类的方法。 根据基于microRNA树的表达框架进行分类可以优化治疗，并确定特异性治疗。
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公开(公告)号：US09803247B2
公开(公告)日：2017-10-31
申请号：US14284256
申请日：2014-05-21
Inventor： Nitzan Rosenfeld , Shai Rosenwald , Iris Barshack , Dvora Nass
IPC: C12Q1/68
CPC classification number: C12Q1/6886 , C12Q2600/112 , C12Q2600/158 , C12Q2600/178
Abstract: The present invention provides a process for classification of specific cancers and tumors origin through the analysis of the expression patterns of specific microRNAs and nucleic acid molecules relating thereto. Classification according to a microRNA expression framework allows optimization of treatment, and determination of specific therapy.
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公开(公告)号：US20150099665A1
公开(公告)日：2015-04-09
申请号：US14572276
申请日：2014-12-16
Inventor： Nitzan Rosenfeld , Shai Rosenwald , Iris Barshack , Gila Lithwick Yanai
IPC: C12Q1/68
CPC classification number: C12Q1/6886 , C12Q2600/112 , C12Q2600/158 , C12Q2600/16 , C12Q2600/178 , Y10T436/143333
Abstract: The present invention provides nucleic acid sequences that are used for identification, classification and diagnosis of lung cancers. The present invention further provides microRNA molecules, as well as various nucleic acid molecules relating thereto or derived therefrom, associated with specific types of lung cancers.
Abstract translation: 本发明提供了用于肺癌鉴定，分类和诊断的核酸序列。 本发明进一步提供与特定类型的肺癌相关的微小RNA分子，以及与之相关的或由其衍生的各种核酸分子。
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Patent Agency Ranking
公开(公告)号：US20190032142A1
公开(公告)日：2019-01-31
申请号：US15909145
申请日：2018-03-01
Applicant: Rosetta Genomics Ltd.
Inventor： Ranit Aharonov , Nitzan Rosenfeld , Shai Rosenwald , Nir Dromi
IPC: C12Q1/6886
Abstract: The present invention provides a process for classification of cancers and tissues of origin through the analysis of the expression patterns of specific microRNAs and nucleic acid molecules relating thereto. Classification according to a microRNA tree-based expression framework allows optimization of treatment, and determination of specific therapy.
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公开(公告)号：US20180127835A1
公开(公告)日：2018-05-10
申请号：US15853258
申请日：2017-12-22
Applicant: Rosetta Genomics Ltd.
Inventor： Ranit Aharonov , Nitzan Rosenfeld , Shai Rosenwald
IPC: C12Q1/6886
CPC classification number: C12Q1/6886 , C12Q2600/158 , C12Q2600/178
Abstract: The present invention provides a process for classification of cancers and tissues of origin through the analysis of the expression patterns of specific microRNAs and nucleic acid molecules relating thereto. Classification according to a microRNA tree-based expression framework allows optimization of treatment, and determination of specific therapy.
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公开(公告)号：US20160115546A1
公开(公告)日：2016-04-28
申请号：US14284256
申请日：2014-05-21
Inventor： Nitzan ROSENFELD , Shai Rosenwald , Iris Barshack , Dvora Nass
IPC: C12Q1/68
CPC classification number: C12Q1/6886 , C12Q2600/112 , C12Q2600/158 , C12Q2600/178
Abstract: The present invention provides a process for classification of specific cancers and tumors origin through the analysis of the expression patterns of specific microRNAs and nucleic acid molecules relating thereto. Classification according to a microRNA expression framework allows optimization of treatment, and determination of specific therapy.
Abstract translation: 本发明通过分析与其相关的特定微小RNA和核酸分子的表达模式，提供了特异性癌症和肿瘤来源的分类方法。 根据microRNA表达框架进行分类可以优化治疗，并确定特异性治疗。
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9.发明授权Gene expression signature for classification of tissue of origin of tumor samples 有权用于肿瘤样品来源组织分类的基因表达特征公开(公告)号：US09096906B2
公开(公告)日：2015-08-04
申请号：US13856190
申请日：2013-04-03
Applicant: Rosetta Genomics Ltd.
Inventor： Ranit Aharonov , Nitzan Rosenfeld , Shai Rosenwald , Nir Dromi
IPC: C12Q1/68
CPC classification number: C12Q1/6886 , C12Q2600/158 , C12Q2600/178
Abstract: The present invention provides a process for classification of cancers and tissues of origin through the analysis of the expression patterns of specific microRNAs and nucleic acid molecules relating thereto. Classification according to a microRNA tree-based expression framework allows optimization of treatment, and determination of specific therapy.
Abstract translation: 本发明通过分析与其有关的特异性微小RNA和核酸分子的表达模式，提供了对癌症和原始组织进行分类的方法。 根据基于microRNA树的表达框架进行分类可以优化治疗，并确定特异性治疗。
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10.发明申请GENE EXPRESSION SIGNATURE FOR CLASSIFICATION OF TISSUE OF ORIGIN OF TUMOR SAMPLES 审中-公开用于分类肿瘤样品原始组织的基因表达标签公开(公告)号：US20140315739A1
公开(公告)日：2014-10-23
申请号：US14320113
申请日：2014-06-30
Applicant: ROSETTA GENOMICS LTD.
Inventor： Ranit Aharonov , Nitzan Rosenfeld , Shai Rosenwald
IPC: C12Q1/68
CPC classification number: C12Q1/6886 , C12Q2600/158 , C12Q2600/178
Abstract: The present invention provides a process for classification of cancers and tissues of origin through the analysis of the expression patterns of specific microRNAs and nucleic acid molecules relating thereto. Classification according to a microRNA tree-based expression framework allows optimization of treatment, and determination of specific therapy.
Abstract translation: 本发明通过分析与其有关的特异性微小RNA和核酸分子的表达模式，提供了对癌症和原始组织进行分类的方法。 根据基于microRNA树的表达框架进行分类可以优化治疗，并确定特异性治疗。
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