公开(公告)号：US4027030A

公开(公告)日：1977-05-31

申请号：US65976076

申请日：1976-02-20

Applicant: ROUSSEL UCLAF

Inventor： POITTEVIN ANDRE ,  FOURNEX ROBERT ,  DAGNAUX MICHELE

IPC: C07D277/20 ,  C07D277/56 ,  C07D277/30

CPC classification number: C07D277/56

Abstract: Novel thiazole carboxamides of the formula I wherein R, R1 and R2 are individually selected from the group consisting of hydrogen and alkyl of 1 to 6 carbon atoms and their non-toxic, pharmaceutically acceptable acid addition salts having a marked antilipolytic activity as well as vasodilatatory and hypoglycemic activity and their preparation.

Abstract translation: 式Ia的新型噻唑甲酰胺其中R 1，R 2和R 2分别选自氢和1至6个碳原子的烷基及其无毒的药学上可接受的酸加成盐，其具有显着的抗水解活性， 以及血管舒张和降血糖活性及其制备。