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公开(公告)号：US3442953A
公开(公告)日：1969-05-06
申请号：US3442953D
申请日：1967-10-10
Applicant: ROUSSEL UCLAF
Inventor： MULLER GEORGES , POITTEVIN ANDRE
IPC: C07C49/755 , C07C49/76
CPC classification number: C07C49/755
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2.发明授权2,3-dimethoxy-berbines substituted in the 10 position and process 失效在十个位置和过程中取代的2,3-DIMETHOXY-BERBINES
公开(公告)号：US3420834A
公开(公告)日：1969-01-07
申请号：US3420834D
申请日：1967-11-24
Applicant: ROUSSEL UCLAF
Inventor： MULLER GEORGES , POITTEVIN ANDRE
IPC: A61K31/00 , C07D455/03 , C07D33/00 , C07D33/38 , C07D35/00
CPC classification number: C07D455/00 , A61K31/00
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Patent Agency Ranking
公开(公告)号：US4027030A
公开(公告)日：1977-05-31
申请号：US65976076
申请日：1976-02-20
Applicant: ROUSSEL UCLAF
Inventor： POITTEVIN ANDRE , FOURNEX ROBERT , DAGNAUX MICHELE
IPC: C07D277/20 , C07D277/56 , C07D277/30
CPC classification number: C07D277/56
Abstract: Novel thiazole carboxamides of the formula I wherein R, R1 and R2 are individually selected from the group consisting of hydrogen and alkyl of 1 to 6 carbon atoms and their non-toxic, pharmaceutically acceptable acid addition salts having a marked antilipolytic activity as well as vasodilatatory and hypoglycemic activity and their preparation.
Abstract translation: 式Ia的新型噻唑甲酰胺其中R 1，R 2和R 2分别选自氢和1至6个碳原子的烷基及其无毒的药学上可接受的酸加成盐，其具有显着的抗水解活性， 以及血管舒张和降血糖活性及其制备。
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公开(公告)号：US3682964A
公开(公告)日：1972-08-08
申请号：US3682964D
申请日：1970-08-31
Applicant: ROUSSEL UCLAF
Inventor： ROUSSEAU GENEVIEVE , ALLAIS ANDRES , POITTEVIN ANDRE
IPC: C07C49/675 , C07C49/697 , C07C57/46 , C07C57/50 , C07C57/62 , C07C59/54 , C07C59/86 , C07C59/88 , C07D311/96 , A61K27/00 , C07D7/04 , C07D65/04
CPC classification number: C07D311/96 , C07C49/675 , C07C49/697 , C07C57/46 , C07C57/50 , C07C57/62 , C07C59/54 , C07C59/86 , C07C59/88
Abstract: Novel spiro benzocyclane acetic acid compounds of the formula
WHEREIN R is selected from the group consisting of hydrogen and linear and branched alkyl of one to four carbon atoms, R1 is selected from the group consisting of hydrogen, chlorine, trifluoromethyl and lower alkoxy, Y is selected from the group consisting of methylene, oxygen and sulfur, n is 2, 3 or 4 and R2 is selected from the group consisting of hydrogen, substituted or unsubstituted alkyl of one to six carbon atoms and cation of nontoxic, pharmaceutically acceptable mineral and organic bases, processes for their preparation and novel intermediates. The compounds of formula I have analgesic and anti-inflammatory properties.Abstract translation: 式WHEREIN R的新型螺环苯并环丙烷乙酸化合物选自氢和1-4个碳原子的直链和支链烷基，R 1选自氢，氯，三氟甲基和低级烷氧基，Y是 选自亚甲基，氧和硫，n为2,3或4，R2选自氢，取代或未取代的1至6个碳原子的烷基和无毒，药学上可接受的矿物质的阳离子 和有机碱，其制备方法和新型中间体。 式I化合物具有止痛和抗炎特性。
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5.发明授权Salts of chrysanthemic acid with 1-p-nitrophenyl - 2-n,n - dimethyl-aminopropane-1,3-diols 失效1-N-硝基苯基-2-N，N-二甲基氨基丙基-1,3-二醇的盐酸盐
公开(公告)号：US3590077A
公开(公告)日：1971-06-29
申请号：US3590077D
申请日：1968-07-05
Applicant: ROUSSEL UCLAF
Inventor： MULLER GEORGES , AMIARD GASTON , POITTEVIN ANDRE , TORELLI VESPERTO
IPC: C07D317/72 , C07C91/20
CPC classification number: C07D317/72
Abstract: OPTICAL ISOMERS OF 1-P-NITROPHENYL-2-N,N-DIMETHYLAMINO-PROPANE-1,3-DIOL AND ACID ADDITION SALTS THEREOF, USEFUL FOR THE SEPARATION OF RACEMIC COMPOUNDS AND PREPARATION THEREOF.
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6.发明授权D(_)-and l(+)-threo-1-p-nitrophenyl-2-n,n-dimethylamino-propane 1,3 - diols and the salts thereof 失效D（_） - 和L（+） - THREO-1-P-NITROPHENYL-2-N，N-二甲基氨基丙烷1,3-二醇及其盐
公开(公告)号：US3499929A
公开(公告)日：1970-03-10
申请号：US3499929D
申请日：1967-01-19
Applicant: ROUSSEL UCLAF
Inventor： MULLER GEORGES , AMIARD GASTON , POITTEVIN ANDRE , TORELLI VESPERTO
IPC: C07D317/72 , C07C91/16
CPC classification number: C07D317/72
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公开(公告)号：US3426027A
公开(公告)日：1969-02-04
申请号：US3426027D
申请日：1965-02-12
Applicant: ROUSSEL UCLAF
Inventor： MULLER GEORGES , POITTEVIN ANDRE
IPC: C07D217/20 , C07D311/76 , C07D455/03 , C07D35/10
CPC classification number: C07D455/00 , C07D217/20 , C07D311/76
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