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公开(公告)号:US20050053665A1
公开(公告)日:2005-03-10
申请号:US10935658
申请日:2004-09-07
IPC分类号: A61K9/00 , A61K9/14 , A61K9/22 , A61K9/68 , A61K9/70 , A61K31/4439 , A61K31/465
CPC分类号: A61K9/0075 , A61K9/0056 , A61K9/0058 , A61K9/006 , A61K9/146 , A61K9/7053 , A61K9/7084 , A61K31/4439 , A61K31/465
摘要: Nicotine-containing pharmaceutical compositions wherein nicotine is absorbed into and/or adsorbed onto cellulose of non-seed organism origin, especially cellulose from algae, bacteria and/or fungi.
摘要翻译: 含尼古丁的药物组合物,其中尼古丁被吸收到非种子生物来源的纤维素上和/或吸附,特别是来自藻类,细菌和/或真菌的纤维素。
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公开(公告)号:US20080286341A1
公开(公告)日:2008-11-20
申请号:US11803865
申请日:2007-05-16
申请人: Sven-Borje Andersson , Gunnar Bergengren , Bengt Bosson , Andreas Hugerth , Fredrik Nicklasson , Roland Olsson
发明人: Sven-Borje Andersson , Gunnar Bergengren , Bengt Bosson , Andreas Hugerth , Fredrik Nicklasson , Roland Olsson
CPC分类号: A61K9/0058 , A23G3/343 , A23G4/062 , A23G2200/00 , A23G2200/10 , A23L33/175 , A24B15/16 , A61K9/0056 , A61K9/2826 , A61K9/2853 , A61K9/2866 , A61K9/2873 , A61K9/288 , A61K31/465
摘要: Coated oral dosage forms for the delivery of nicotine in any form to a subject by rapid intraoral delivery of nicotine comprising at least one core, nicotine in any form and/or a nicotine mimicking agent, at least one coating layer and optionally at least one or more other additives, wherein said at last one coating layer is buffered, whereby is used at least one amino acid as buffering agent. Also contemplated are a method for the delivery of nicotine in any form, a method for the reduction of the urge to smoke or use tobacco as well as a method for producing said coated product and use of the same for obtaining a rapid intraoral uptake of nicotine.
摘要翻译: 用于将任何形式的尼古丁以任何形式递送至受试者的涂覆的口服剂型包括至少一种核心,任何形式的尼古丁和/或尼古丁模拟剂,至少一种包衣层和任选的至少一种或多种 更多其它添加剂,其中所述最后一个涂层被缓冲,由此使用至少一个氨基酸作为缓冲剂。 还考虑了以任何形式递送尼古丁的方法,用于减少吸烟或使用烟草的欲望的方法以及用于生产所述包衣产品的方法及其用于获得尼古丁快速口内摄取的方法 。
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公开(公告)号:US20080286340A1
公开(公告)日:2008-11-20
申请号:US11803747
申请日:2007-05-16
申请人: Sven-Borje Andersson , Gunnar Bergengren , Bengt Bosson , Andreas Hugerth , Fredrik Nicklasson , Roland Olsson
发明人: Sven-Borje Andersson , Gunnar Bergengren , Bengt Bosson , Andreas Hugerth , Fredrik Nicklasson , Roland Olsson
CPC分类号: A61K9/006 , A23G3/44 , A23G4/14 , A23L33/175 , A24B15/16 , A61K9/0056 , A61K9/0058 , A61K31/465
摘要: A pharmaceutical oral formulation for delivering nicotine in any form to a subject by transmucosal uptake in the oral cavity comprising nicotine in any form, wherein said oral formulation is buffered with at least one amino acid, preferably at least one endogenous amino acid. Also contemplated is a method for the oral delivery of nicotine in any form, a method for the reduction of the urge to smoke or use tobacco as well as methods for manufacturing the oral formulation, the use of said oral formulation for obtaining transmucosal uptake of nicotine in the oral cavity of a subject, and use of nicotine for the production of an oral formulation as per above for the treatment of a disease selected from the group consisting of tobacco or nicotine dependence, Alzheimer's disease, Crohn's disease, Parkinson's disease, Tourette's syndrome, ulcerous colitis and post-smoking-cessation weight control.
摘要翻译: 一种药物口服制剂,其用于通过口腔内经粘膜摄取将任何形式的尼古丁以任何形式递送至任何形式的尼古丁,其中所述口服制剂用至少一种氨基酸,优选至少一种内源性氨基酸缓冲。 还考虑了以任何形式口服输送尼古丁的方法,减少吸烟或使用烟草的欲望的方法以及制备口服制剂的方法,所述口服制剂用于获得尼古丁的经粘膜摄取 在受试者的口腔中,以及使用尼古丁制备如上所述的口服制剂用于治疗选自烟草或尼古丁依赖性疾病,阿尔茨海默氏病,克罗恩病,帕金森氏病,图雷特综合征 ,溃疡性结肠炎和戒烟后重量控制。
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公开(公告)号:US20070269386A1
公开(公告)日:2007-11-22
申请号:US11444787
申请日:2006-06-01
申请人: Per Steen , Darek Dymitrowicz , Andreas Hugerth , Asa Waltermo , Magnus Palsson , Roland Olsson , Fredrik Nicklasson , Anette Schluter , Kristina Thyresson , Seema K. Mody , Bengt Bosson , Katarina Lindell , Gregory Koll
发明人: Per Steen , Darek Dymitrowicz , Andreas Hugerth , Asa Waltermo , Magnus Palsson , Roland Olsson , Fredrik Nicklasson , Anette Schluter , Kristina Thyresson , Seema K. Mody , Bengt Bosson , Katarina Lindell , Gregory Koll
IPC分类号: A61K31/4439 , A61K9/68
CPC分类号: A61K9/0056 , A61K9/0058 , A61K9/006 , A61K9/12 , A61K9/2013 , A61K9/2018 , A61K9/4858 , A61K9/7007 , A61K31/465
摘要: A pharmaceutical oral formulation for delivering nicotine in any form to a subject by transmucosal uptake in the oral cavity comprising nicotine in any form, wherein said oral formulation is buffered with at least trometamol. Also contemplated is a method for the oral delivery of nicotine in any form, a method for the reduction of the urge to smoke or use tobacco as well as methods for manufacturing the oral formulation, the use of the oral formulation for obtaining transmucosal uptake of nicotine in the oral cavity of a subject, and use of nicotine for the production of an oral formulation for the treatment of a disease selected from the group consisting of tobacco or nicotine dependence, Alzheimer's disease, Crohn's disease, Parkinson's disease, Tourette's syndrome, ulcerous colitis and post-smoking-cessation weight control.
摘要翻译: 一种药物口服制剂,其用于通过口腔内经粘膜摄取将任何形式的尼古丁递送至受试者,其包含任何形式的尼古丁,其中所述口服制剂至少使用氨丁三醇缓冲。 还考虑了以任何形式口服输送尼古丁的方法,用于减少吸烟或使用烟草的欲望的方法以及制备口服制剂的方法,口服制剂用于获得尼古丁的经粘膜摄取的方法 在对象的口腔中,以及使用尼古丁来制备用于治疗选自烟草或尼古丁依赖性疾病,阿尔茨海默氏病,克罗恩病,帕金森病,图雷特综合征,溃疡性结肠炎的口服制剂 和戒烟后重量控制。
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公开(公告)号:US20070163610A1
公开(公告)日:2007-07-19
申请号:US11686842
申请日:2007-03-15
IPC分类号: A24F47/00
CPC分类号: A61K9/0002 , A61K31/465 , A61K45/06
摘要: This invention relates to a liquid pharmaceutical formulation for delivering nicotine to a subject. This invention also relates to a method and a system for delivering nicotine as well as manufacturing and use of said liquid pharmaceutical formulation.
摘要翻译: 本发明涉及用于向受试者递送尼古丁的液体药物制剂。 本发明还涉及一种用于递送尼古丁以及所述液体药物制剂的制造和使用的方法和系统。
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