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1.发明申请Novel Lipids and Compositions for Intracellular Delivery of Biologically Active Compounds 有权用于生物活性化合物细胞内递送的新型脂质和组合物公开(公告)号：US20120295832A1
公开(公告)日：2012-11-22
申请号：US13466640
申请日：2012-05-08
申请人： Rainer Constien , Anke Geick , Philipp Hadwiger , Torsten Haneke , Ludger Markus Ickenstein , Carla Alexandra Hernandez Prata , Andrea Schuster , Timo Weide
发明人： Rainer Constien , Anke Geick , Philipp Hadwiger , Torsten Haneke , Ludger Markus Ickenstein , Carla Alexandra Hernandez Prata , Andrea Schuster , Timo Weide
IPC分类号： C07D241/04 , C07C217/42 , A61K38/02 , A61K31/70 , A61K31/7052 , C07C211/13 , A61K47/18 , B82Y5/00
CPC分类号： A61K9/145 , A61K9/1271 , A61K31/575 , A61K31/70 , A61K31/7088 , A61K31/713 , A61K38/02 , A61K39/00 , A61K47/18 , A61K47/22 , B82Y5/00 , C07C211/11 , C07C211/13 , C07C211/14 , C07C211/22 , C07C217/08 , C07C217/28 , C07C217/42 , C07D241/04 , C07D295/13 , C07D295/30
摘要： The present invention provides novel amino-lipids, compositions comprising such amino-lipids and methods of producing them. In addition, lipid nanoparticles comprising the novel amino-lipids and a biologically active compound are provided, as well as methods of production and their use for intracellular drug delivery.
摘要翻译： 本发明提供新的氨基脂质，包含这种氨基脂质的组合物及其制备方法。 此外，提供了包含新型氨基脂质和生物活性化合物的脂质纳米粒子，以及生产方法及其用于细胞内药物递送。
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2.发明授权Lipids and compositions for intracellular delivery of biologically active compounds 有权用于细胞内递送生物活性化合物的脂质和组合物公开(公告)号：US08691750B2
公开(公告)日：2014-04-08
申请号：US13466640
申请日：2012-05-08
申请人： Rainer Constien , Anke Geick , Philipp Hadwiger , Torsten Haneke , Ludger Markus Ickenstein , Carla Alexandra Hernandez Prata , Andrea Schuster , Timo Weide
发明人： Rainer Constien , Anke Geick , Philipp Hadwiger , Torsten Haneke , Ludger Markus Ickenstein , Carla Alexandra Hernandez Prata , Andrea Schuster , Timo Weide
CPC分类号： A61K9/145 , A61K9/1271 , A61K31/575 , A61K31/70 , A61K31/7088 , A61K31/713 , A61K38/02 , A61K39/00 , A61K47/18 , A61K47/22 , B82Y5/00 , C07C211/11 , C07C211/13 , C07C211/14 , C07C211/22 , C07C217/08 , C07C217/28 , C07C217/42 , C07D241/04 , C07D295/13 , C07D295/30
摘要： The present invention provides novel amino-lipids, compositions comprising such amino-lipids and methods of producing them. In addition, lipid nanoparticles comprising the novel amino-lipids and a biologically active compound are provided, as well as methods of production and their use for intracellular drug delivery.
摘要翻译： 本发明提供新的氨基脂质，包含这种氨基脂质的组合物及其制备方法。 此外，提供了包含新型氨基脂质和生物活性化合物的脂质纳米粒子，以及生产方法及其用于细胞内药物递送。
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