Coating composition for taste masking coating and methods for their application and use
    1.
    发明申请
    Coating composition for taste masking coating and methods for their application and use 审中-公开
    用于掩味涂层的涂料组合物及其应用和用途的方法

    公开(公告)号:US20060159758A1

    公开(公告)日:2006-07-20

    申请号:US10538354

    申请日:2003-12-11

    IPC分类号: A61K9/24

    摘要: The present invention relates to coating compositions for taste masking and methods for applying the coating compositions to dosage forms to mask the taste of a medicinal substance. The taste masking coating compositions generally include a copolymer of acrylate and methacrylate with a quaternary ammonium group in combination with sodium carboxymethylcellulose and a polyvinyl alcohol-polyethylene glycol copolymer.

    摘要翻译: 本发明涉及用于掩味的涂料组合物和将涂料组合物施用于剂型以掩盖药物的味道的方法。 掩味涂料组合物通常包括丙烯酸酯和甲基丙烯酸酯与季铵基团与羧甲基纤维素钠和聚乙烯醇 - 聚乙二醇共聚物的共聚物的共聚物。

    Method and apparatus for configuration management in communications
networks

    公开(公告)号:US5832503A

    公开(公告)日:1998-11-03

    申请号:US394143

    申请日:1995-02-24

    IPC分类号: H04L12/24 G06F17/30

    摘要: Apparatus and method for monitoring parameters that govern the operational characteristics of a network device, including the use of templates for generating configuration records of network devices of a selected model type. A database of models is provided, each model representing an associated network device and including attribute values for the parameters of the associated network device. Templates are used to screen a model in order to retrieve values for each of the attributes and create a configuration record. The configuration records may be stored in the configuration manager or other storage device, and/or transferred to the pre-existing model database for use by a network management system in reconfiguring the associated network devices. This system for configuration management is less time consuming, expensive, and error prone than prior systems.

    Bioavailable dosage form of isotretinoin
    8.
    发明授权
    Bioavailable dosage form of isotretinoin 失效
    异维A酸的生物可利用剂型

    公开(公告)号:US06740337B2

    公开(公告)日:2004-05-25

    申请号:US09829246

    申请日:2001-04-09

    IPC分类号: A61K914

    CPC分类号: A61K9/14 A61K9/4858 A61K31/07

    摘要: The present invention relates to a bioavailable pharmaceutical composition of 13-cis vitamin A acid (also known as 13-cis retinoic acid and isotretinoin) and a process for preparing the same. 13-cis vitamin A acid is a relatively water insoluble compound that degrades when exposed to light and atmospheric oxygen. Due to its instability and relative insolubility, the bioavailability of the drug after oral administration is difficult to achieve and has always been a challenge to a development pharmacist. It would therefore be desirable to provide a dosage form in which the drug is stable and predictably bioavailable.

    摘要翻译: 本发明涉及13-顺式维生素A酸(也称为13-顺式视黄酸和异维A酸)的生物可利用药物组合物及其制备方法。 13-顺式维生素A酸是一种相对不溶于水的化合物,当暴露于光和大气中时会降解。 由于其不稳定性和相对不溶性,口服给药后药物的生物利用度难以实现,并且一直是开发药剂师的挑战。 因此,期望提供其中药物是稳定的并且可预测地具有生物利用度的剂型。