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公开(公告)号：US20100041162A1
公开(公告)日：2010-02-18
申请号：US12513403
申请日：2007-10-26
申请人： Ralf Hoffmann , Helga Hummel , Volker Weiler
发明人： Ralf Hoffmann , Helga Hummel , Volker Weiler
CPC分类号： G01N33/6812 , C07F5/025 , C07K14/00 , G01N33/532 , G01N33/58 , G01N33/6851 , G06F19/28 , Y10T436/13
摘要： The present invention relates to the tagging of Histidine in polypeptides with arylboronic acid tagging reagents. The present invention further describes methods and devices to identify proteins in a sample by isolating and identifying Histidine-comprising peptides from one protein sample or a pool of protein samples. The present invention further describes databases of Histidine-comprising peptides from in silico cleaved proteins and their use in the identification of proteins.
摘要翻译： 本发明涉及用芳基硼酸标记试剂在多肽中标记组氨酸。 本发明还描述了通过从一个蛋白质样品或一组蛋白质样品中分离和鉴定含有组氨酸的肽来鉴定样品中蛋白质的方法和装置。 本发明进一步描述了来自硅片切割的蛋白质的组氨酸肽的数据库及其在鉴定蛋白质中的用途。
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公开(公告)号：US08097463B2
公开(公告)日：2012-01-17
申请号：US12513403
申请日：2007-10-26
申请人： Ralf Hoffmann , Helga Hummel , Volker Weiler
发明人： Ralf Hoffmann , Helga Hummel , Volker Weiler
IPC分类号： C07F5/02
CPC分类号： G01N33/6812 , C07F5/025 , C07K14/00 , G01N33/532 , G01N33/58 , G01N33/6851 , G06F19/28 , Y10T436/13
摘要： Tagging of Histidine in polypeptides with arylboronic acid tagging reagents for identifying proteins in a sample by isolating and identifying Histidine-comprising peptides from one protein sample or a pool of protein samples. Databases of Histidine-including peptides from in silico cleaved proteins are uses in the identification of proteins.
摘要翻译： 通过分离和鉴定来自一个蛋白质样品或蛋白质样品池的含有组氨酸的肽，用芳基硼酸标记试剂标记样品中蛋白质的多肽中的组氨酸。 来自硅裂解蛋白质的组氨酸包括肽的数据库是鉴定蛋白质的用途。
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公开(公告)号：US20120092242A1
公开(公告)日：2012-04-19
申请号：US13259661
申请日：2010-03-18
申请人： Matthias Wendt , Helga Hummel , Wolfgang Otto Budde , Hans Peter Loebl , Volker Weiler , Thomas Juestel , Jacqueline Merikhi
发明人： Matthias Wendt , Helga Hummel , Wolfgang Otto Budde , Hans Peter Loebl , Volker Weiler , Thomas Juestel , Jacqueline Merikhi
IPC分类号： G09G3/36 , G02F1/13357
摘要： A system comprising a device for placement in front of a display device, such as a TV screen, to change the optical properties of light received by a user observing said display device, when the display device is in an off state or standby state, while when the display device is in an on state, the device appears transparent.
摘要翻译： 一种系统，包括用于放置在诸如TV屏幕的显示装置前面的装置，以在显示装置处于关闭状态或待机状态时改变由观察所述显示装置的用户接收的光的光学特性，同时 当显示设备处于打开状态时，设备显示为透明状态。
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公开(公告)号：US08050477B2
公开(公告)日：2011-11-01
申请号：US12162671
申请日：2007-01-22
IPC分类号： A61N5/10
CPC分类号： A61N5/1031
摘要： An improved radiation therapy planning procedure is suggested. The procedure comprises the steps of specifying and determining the absolute grade of cell degeneracy by in-vitro tests, whereby marker(s) indicative for specific cell degeneracy are detected and quantified, establishing a biology-based segmentation of areas with similar grade of relative cell degeneracy and applying the absolute grade of cell degeneracy to the biology-based segmentation data, thereby establishing an improved radiation therapy planning procedure. Moreover, the present invention suggests a system for an improved radiation therapy planning procedure and its use in procedures of diagnosis and/or therapy management of cancer.
摘要翻译： 建议采用改进的放射治疗计划程序。 该方法包括以下步骤：通过体外测试来指定和确定细胞退化的绝对等级，由此检测和量化指示特异性细胞退化的标志物，建立具有相似等级的相对细胞的区域的基于生物学的分割 退化并将绝对等级的细胞退化应用于基于生物学的分割数据，从而建立改进的放射治疗计划程序。 此外，本发明提出了一种改进的放射治疗计划程序及其在癌症诊断和/或治疗管理程序中的应用的系统。
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公开(公告)号：US20080206152A1
公开(公告)日：2008-08-28
申请号：US11916548
申请日：2006-06-01
申请人： Ralf Hoffmann , Helga Hummel , Matthias Wendt
发明人： Ralf Hoffmann , Helga Hummel , Matthias Wendt
CPC分类号： G01N33/5091 , G01N33/6842
摘要： The present invention relates to in vivo expression profiling using a plurality of specific targeting moieties each labelled with a different compound which allows to identify simultaneously the binding of each targeting moiety to a target.
摘要翻译： 本发明涉及使用多个特异性靶向部分的体内表达谱，每个特异性靶向部分用不同的化合物标记，其允许同时鉴定每个靶向部分与靶标的结合。
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公开(公告)号：US20090028408A1
公开(公告)日：2009-01-29
申请号：US12162671
申请日：2007-01-22
IPC分类号： A61N5/10
CPC分类号： A61N5/1031
摘要： An improved radiation therapy planning procedure is suggested. The procedure comprises the steps of specifying and determining the absolute grade of cell degeneracy by in-vitro tests, whereby marker(s) indicative for specific cell degeneracy are detected and quantified, establishing a biology-based segmentation of areas with similar grade of relative cell degeneracy and applying the absolute grade of cell degeneracy to the biology-based segmentation data, thereby establishing an improved radiation therapy planning procedure. Moreover, the present invention suggests a system for an improved radiation therapy planning procedure and its use in procedures of diagnosis and/or therapy management of cancer
摘要翻译： 建议采用改进的放射治疗计划程序。 该方法包括以下步骤：通过体外测试来指定和确定细胞退化的绝对等级，由此检测和量化指示特异性细胞退化的标志物，建立具有相似等级的相对细胞的区域的基于生物学的分割 退化并将绝对等级的细胞退化应用于基于生物学的分割数据，从而建立改进的放射治疗计划程序。 此外，本发明提出了一种改进的放射治疗计划程序及其在癌症诊断和/或治疗管理程序中的应用的系统
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7.发明申请TARGETING CONTRAST AGENTS OR TARGETING THERAPEUTIC AGENTS FOR MOLECULAR IMAGING AND THERAPY 审中-公开针对分子成像和治疗的对照药物或靶向治疗药物公开(公告)号：US20090238767A1
公开(公告)日：2009-09-24
申请号：US11721382
申请日：2005-12-12
CPC分类号： A61K49/0067 , A61K51/0402 , A61K51/1255 , B82Y5/00 , B82Y10/00 , Y10T428/2984
摘要： This invention discloses a method of synthesizing targeting contrast agents for molecular imaging and targeting diagnosis and therapy, targeting contrast agents and targeting therapeutic agents and their use.
摘要翻译： 本发明公开了一种合成靶向造影剂用于分子成像和靶向诊断和治疗，靶向造影剂和靶向治疗剂及其用途的方法。
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8.发明申请Use of a Composite or Composition of Diamond and Other Material for Analysis of Analytes 审中-公开使用金刚石和其他材料的复合材料或组合物分析分析物公开(公告)号：US20070218564A1
公开(公告)日：2007-09-20
申请号：US11568191
申请日：2005-04-13
申请人： Peter Bachmann , Volker Van Elsbergen , Ralf Hoffmann , Helga Hummel , Carolina Ribbing , Detlef Wiechert
发明人： Peter Bachmann , Volker Van Elsbergen , Ralf Hoffmann , Helga Hummel , Carolina Ribbing , Detlef Wiechert
IPC分类号： G01N1/00
CPC分类号： H01J49/0418 , Y10T436/25
摘要： The present invention relates to the use of composites or compositions of diamond/non-diamond material, e.g. diamond/non-diamond carbon material for chemical or biological analysis. The invention further relates to the use of this material in separation adherence and detection of chemical of biological samples. Applications of either structurized substrates or mixed phase particles of this material include but are not limited to processes which involve desorption-ionization of a sample, more specifically mass spectroscopy.
摘要翻译： 本发明涉及金刚石/非金刚石材料的复合材料或组合物的使用，例如， 用于化学或生物分析的金刚石/非金刚石碳材料。 本发明还涉及这种材料在分离粘附和生物样品化学物质检测中的应用。 这种材料的结构化底物或混合相颗粒的应用包括但不限于涉及样品的解吸电离的方法，更具体地说是质谱法。
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公开(公告)号：US20060170331A1
公开(公告)日：2006-08-03
申请号：US10548244
申请日：2004-03-01
申请人： Dietrich Bertram , Helga Hummel , Thomas Justel
发明人： Dietrich Bertram , Helga Hummel , Thomas Justel
CPC分类号： B82Y30/00 , B82Y10/00 , B82Y20/00 , C09K11/883 , H05B33/14
摘要： The invention describes an electroluminescent device equipped with a first electrode and a second electrode and with a compressed optical layer with quantum dots, wherein the compressed optical layer emits radiation under the influence of an electrical field. The electroluminescent device in accordance with the invention exhibits increased stability and improved efficiency and brightness.
摘要翻译： 本发明描述了配备有第一电极和第二电极以及具有量子点的压缩光学层的电致发光器件，其中压缩光学层在电场的影响下发射辐射。 根据本发明的电致发光器件表现出增加的稳定性和改进的效率和亮度。
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10.发明申请Electroluminescent compounds from binuclear, trinuclear, oligonuclear, and/or polynuclear metal complexes 审中-公开来自双核，三核，寡核和/或多核金属络合物的电致发光化合物公开(公告)号：US20070096638A1
公开(公告)日：2007-05-03
申请号：US10578651
申请日：2004-11-04
申请人： Herbert Boerner , Helga Hummel
发明人： Herbert Boerner , Helga Hummel
CPC分类号： C09K11/06 , C07F5/003 , C09K2211/182 , H01L51/0059 , H01L51/0062 , H01L51/0089 , H05B33/14
摘要： This invention relates to electroluminescent compounds and in particular to electroluminescent compounds used in organic LED's (OLEDs).
摘要翻译： 本发明涉及电致发光化合物，特别涉及用于有机LED（OLED）中的电致发光化合物。
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