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    Hemodialyzer having improved dialysate perfusion
    1.
    发明授权
    Hemodialyzer having improved dialysate perfusion 有权
    血液透析器具有改善的透析液灌注

    公开(公告)号：US06623638B2

    公开(公告)日：2003-09-23

    申请号：US09871864

    申请日：2001-06-01

    申请人： Randolph H. Watkins ,  James S. Slepicka ,  Michael R. Prisco

    发明人： Randolph H. Watkins ,  James S. Slepicka ,  Michael R. Prisco

    IPC分类号： B01D6302

    CPC分类号： B01D63/02 ,  A61M1/16 ,  A61M1/1627 ,  A61M2202/0498 ,  A61M2205/15 ,  B01D61/20 ,  B01D2313/10 ,  B01D2313/12 ,  B01D2313/21

    摘要： A dialyzer is provided comprising a casing defining an interior and including a dialysate inlet and a dialysate outlet. A plurality of fibers are located in the interior of the casing and define a fiber bundle. A dialysate inlet fluid channel is provided in fluid communication with the dialysate inlet and includes a plurality of flutes that extend into a portion of the fiber bundles, the flutes define an opening for allowing dialysate to flow from the inlet fluid channel into the interior of the casing. Methods of providing dialysis are also provided.

    摘要翻译： 提供了透析器，其包括限定内部的壳体，并且包括透析液入口和透析液出口。 多个纤维位于壳体的内部并限定纤维束。 提供透析液入口流体通道与透析液入口流体连通，并且包括延伸到纤维束的一部分中的多个凹槽，凹槽限定开口，用于允许透析液从入口流体通道流入到内部 套管。 还提供了提供透析的方法。

    DIALYSIS SYSTEMS AND METHODS INCLUDING CASSETTE WITH AIR REMOVAL
    2.
    发明申请
    DIALYSIS SYSTEMS AND METHODS INCLUDING CASSETTE WITH AIR REMOVAL 有权
    DIALYSIS系统和方法，包括空气移除CASSETTE

    公开(公告)号：US20120065581A1

    公开(公告)日：2012-03-15

    申请号：US13301306

    申请日：2011-11-21

    申请人： Robert W. Childers ,  Donald D. Busby ,  Michael E. Hogard ,  Michael R. Prisco ,  Atif M. Yardimci ,  James C. Laird

    发明人： Robert W. Childers ,  Donald D. Busby ,  Michael E. Hogard ,  Michael R. Prisco ,  Atif M. Yardimci ,  James C. Laird

    IPC分类号： A61M1/28

    CPC分类号： A61M1/1658 ,  A61M1/166 ,  A61M1/3627 ,  A61M2205/128

    摘要： In an embodiment, a dialysis fluid cassette is disclosed. The cassette includes a plurality of walls defining at least one valve chamber, a dialysis fluid inlet, a dialysis fluid outlet and a dialysis fluid pathway. The cassette further includes a baffle extending from a first one of the walls to an opposing second one of the walls. The baffle includes an end fixed to a third one of the plurality of walls and a free end. The fixed end separates the dialysis fluid inlet from the dialysis fluid outlet and the baffle and the plurality of walls are constructed and arranged such that the flow of dialysis fluid along the pathway defined in part by the baffle slows as the flow approaches the free end of the baffle.

    摘要翻译： 在一个实施例中，公开了透析流体盒。 盒子包括限定至少一个阀室，透析流体入口，透析流体出口和透析流体通道的多个壁。 所述盒还包括从所述壁中的第一壁延伸到相对的第二壁之间的挡板。 挡板包括固定到多个壁中的第三个壁的端部和自由端。 固定端将透析流体入口与透析流体出口和挡板分离，并且构造和布置多个壁，使得沿着部分由挡板限定的路径的透析流体的流动随着流体接近自由端的速度而减慢 挡板。

    DIALYSIS SYSTEM HAVING INDUCTIVE HEATING
    3.
    发明申请
    DIALYSIS SYSTEM HAVING INDUCTIVE HEATING 失效
    具有电感加热功能的透析系统

    公开(公告)号：US20080200866A1

    公开(公告)日：2008-08-21

    申请号：US11675470

    申请日：2007-02-15

    申请人： Michael R. Prisco ,  Yuanpang S. Ding ,  Tan-Cheng Chou ,  Tom Johnson

    发明人： Michael R. Prisco ,  Yuanpang S. Ding ,  Tan-Cheng Chou ,  Tom Johnson

    IPC分类号： A61M1/28

    CPC分类号： A61M5/44 ,  A61M1/16 ,  A61M1/1605 ,  A61M2205/127 ,  A61M2205/3368 ,  A61M2205/3653 ,  A61M2205/50

    摘要： A medical fluid machine includes (i) a pump that pumps a medical fluid and (ii) a heater that heats the medical fluid, the heater including an electrically insulative housing, at least one flat sheet of electrically conductive material suitable for contacting the medical fluid, the sheet disposed within the insulative housing, the sheet defining a flow path for the medical fluid in which the medical fluid changes direction at least one time, a primary coil of a transformer located outside the insulative housing, the primary coil configured to induce a current into the at least one conductive sheet, creating heat that may be transferred to the medical fluid.

    摘要翻译： 医疗流体机械包括（i）泵送医用流体的泵和（ii）加热医用流体的加热器，加热器包括电绝缘壳体，至少一个导电材料平板，适于接触医用流体 设置在所述绝缘壳体内的片材，所述片材限定用于医疗流体至少一次改变方向的医疗流体的流动路径，位于绝缘壳体外部的变压器的初级线圈，所述初级线圈被配置为诱导 电流进入至少一个导电片，产生可传送到医用流体的热量。

    Solution and method for maintaining patency of a catheter
    5.
    发明授权
    Solution and method for maintaining patency of a catheter 失效
    用于维持导管通畅的方法和方法

    公开(公告)号：US4929242A

    公开(公告)日：1990-05-29

    申请号：US349948

    申请日：1989-05-08

    申请人： Vince C. Desecki ,  Michael R. Prisco

    发明人： Vince C. Desecki ,  Michael R. Prisco

    IPC分类号： A61M25/00

    CPC分类号： A61M25/0017

    摘要： A solution is described that can be used to maintain the patency of an I.V. catheter or other vascular access device having a lumen. The density and osmolarity of the solution are adjusted so that the density and osmolarity of the solution are approximately equal to the density and osmolarity of whole blood in a patient. The solution can be injected into the lumen of the vascular access device to prevent blood from the patient from entering the lumen.

    摘要翻译： 描述了可用于维持I.V.的通畅的解决方案。 导管或具有内腔的其它血管通路装置。 调节溶液的密度和渗透压，使得溶液的密度和渗透压近似等于患者中全血的密度和渗透压。 该溶液可以注射到血管进入装置的内腔中，以防止来自患者的血液进入管腔。

    DIALYSIS SYSTEMS HAVING AIR TRAPS WITH INTERNAL STRUCTURES TO ENHANCE AIR REMOVAL
    9.
    发明申请
    DIALYSIS SYSTEMS HAVING AIR TRAPS WITH INTERNAL STRUCTURES TO ENHANCE AIR REMOVAL 有权
    具有内部结构的空气导轨的透析系统，以加强空气移除

    公开(公告)号：US20090084718A1

    公开(公告)日：2009-04-02

    申请号：US11865577

    申请日：2007-10-01

    申请人： Michael R. Prisco ,  Atif M. Yardimci ,  Serhan Acikgoz ,  James C. Laird ,  Shincy J. Maliekkal ,  Justin B. Rohde

    发明人： Michael R. Prisco ,  Atif M. Yardimci ,  Serhan Acikgoz ,  James C. Laird ,  Shincy J. Maliekkal ,  Justin B. Rohde

    IPC分类号： B01D35/01

    CPC分类号： A61M1/1658 ,  A61M1/288 ,  A61M1/3627 ,  A61M2205/12 ,  A61M2205/128 ,  B01D19/0042

    摘要： A dialysis fluid cassette includes a rigid portion defining first and second valve chambers, the rigid portion further defining an air separation chamber in fluid communication with the first and second valve chambers, the air separation chamber including a baffle and structured such that when the cassette is placed in a dialysis instrument, (i) the baffle extends upwardly from a bottom of the air separation chamber and (ii) first and second openings to the air separation chamber, communicating fluidly and respectively with the first and second valve chambers, are located near the bottom of the air separation chamber, such that the dialysis fluid is forced up one side of the baffle and down the other side of the baffle when flowing through the air separation chamber.

    摘要翻译： 透析液体盒包括限定第一和第二阀室的刚性部分，刚性部分进一步限定与第一和第二阀室流体连通的空气分离室，空气分离室包括挡板并构造成使得当盒式磁带 放置在透析仪器中，（i）挡板从空气分离室的底部向上延伸，和（ii）第一和第二开口到达空气分离室，与第一和第二阀室流体连通，分别位于靠近 空气分离室的底部，使得透析流体在流过空气分离室时被迫上挡板的一侧并且在挡板的另一侧下方。

    Fluid flow regulator
    10.
    发明授权
    Fluid flow regulator 失效
    流体流量调节器

    公开(公告)号：US5520661A

    公开(公告)日：1996-05-28

    申请号：US279938

    申请日：1994-07-25

    申请人： Birendra K. Lal ,  Yuan-Pang S. Ding ,  Michael R. Prisco ,  Rebecca S. Black ,  Robert Passaglia ,  James Richardson

    发明人： Birendra K. Lal ,  Yuan-Pang S. Ding ,  Michael R. Prisco ,  Rebecca S. Black ,  Robert Passaglia ,  James Richardson

    IPC分类号： A61M5/168 ,  G05D7/01 ,  A61M5/00

    CPC分类号： A61M5/16881 ,  G05D7/0113 ,  Y10T137/7879

    摘要： The present invention provides an intravenous fluid flow regulator 10 for controlling the I.V. administration of medical fluid to a patient. The fluid flow regulator 10 provides a housing 12 having a top 18 and a bottom 20. A flexible diaphragm 14 is positioned within housing 12. A diaphragm holder 16 is provided inside housing 12 for holding a sealing edge 56 of flexible diaphragm 14 in fluid sealing engagement with diaphragm holder 16. The housing 12 and flexible diaphragm 14 define an inlet fluid reservoir 62 and an outlet fluid reservoir 64. The diaphragm holder 16 defines a by-pass fluid channel 54 from inlet fluid reservoir 62, around diaphragm 14, to outlet fluid reservoir 64. The flexible diaphragm 14 being flexible to alternatively move into inlet fluid reservoir 62 and outlet fluid reservoir 64 depending on a fluid pressure differential between inlet fluid reservoir 62 and outlet fluid reservoir 64. A fluid inlet 24 is connected to housing top 18 to provide an inlet fluid passage 27 from an I.V. bag containing medical fluid to inlet fluid reservoir 62. A fluid outlet 34 is connected to housing bottom 20 to provide an outlet fluid passage 44 from outlet fluid reservoir 64 to the patient. At least one rib 48 connected to bottom 20 is provided to prevent movement of flexible diaphragm 14 into outlet fluid reservoir 64 when flexible diaphragm 14 moves into outlet fluid reservoir 64 a predetermined distance.

    摘要翻译： 本发明提供了一种静脉内流体流量调节器10，用于控制I.V. 向患者施用医用流体。 流体流量调节器10提供具有顶部18和底部20的壳体12.柔性隔膜14定位在壳体12内。隔膜保持器16设置在壳体12内部，用于将柔性隔膜14的密封边缘56保持在流体密封 与隔膜保持器16的接合。壳体12和柔性隔膜14限定入口流体储存器62和出口流体储存器64.隔膜支架16限定来自入口流体储存器62的周边流体通道54，围绕隔膜14到出口 流体储存器64.根据进口流体储存器62和出口流体储存器64之间的流体压力差，柔性隔膜14可挠曲地交替地进入入口流体储存器62和出口流体储存器64.流体入口24连接到壳体顶部18 以从IV提供入口流体通道27 流体出口34连接到壳体底部20，以从出口流体储存器64向患者提供出口流体通道44。 连接到底部20的至少一个肋48被设置成当柔性隔膜14移动到出口流体储存器64中预定距离时，以防止柔性隔膜14移动到出口流体储存器64中。