公开(公告)号：US20080247050A1

公开(公告)日：2008-10-09

申请号：US12053368

申请日：2008-03-21

申请人： Renhu Shi ,  Anke Vogelgsang ,  Thomas Bocher ,  Werner Kleinschmidt

发明人： Renhu Shi ,  Anke Vogelgsang ,  Thomas Bocher ,  Werner Kleinschmidt

IPC分类号： G02B21/02

CPC分类号： G02B21/02 ,  G02B27/52

摘要： The invention relates to a microscope objective which consists of at least four lenses or groups of lenses and can preferably be used to improve image contrast.According to the invention, a phase plate, aligned concentrically to the optical axis, can be integrated into and taken out of the air space between the first lens and the second lens, as viewed from the object side.The defined arrangement of the phase plate and the associated shift of the real pupil into the air space between the first two lenses or groups of lenses, respectively, of the microscope objective allows a microscope objective, initially designed as a bright-field variant, to be redesigned as a phase contrast variant with relative ease.

摘要翻译： 本发明涉及由至少四个透镜或透镜组组成的显微镜物镜，并且可以优选地用于改善图像对比度。 根据本发明，从对象侧观察，与光轴同心对准的相位板可以集成到第一透镜和第二透镜之间的空间中并从其中取出。 相位板的限定布置以及分别在显微镜物镜的前两个透镜或透镜组之间的真实光瞳相关位移到空间中允许将最初被设计为亮场变体的显微镜物镜 相对容易地重新设计为相位差变体。

公开(公告)号：US07672057B2

公开(公告)日：2010-03-02

申请号：US12053368

申请日：2008-03-21

申请人： Renhu Shi ,  Anke Vogelgsang ,  Thomas Bocher ,  Werner Kleinschmidt

发明人： Renhu Shi ,  Anke Vogelgsang ,  Thomas Bocher ,  Werner Kleinschmidt

IPC分类号： G02B21/02

CPC分类号： G02B21/02 ,  G02B27/52

摘要： A microscope objective having at least four lenses or groups of lenses and which can be used to improve image contrast. According to the invention, a phase plate, aligned concentrically to the optical axis, can be integrated into and taken out of the air space between the first lens and the second lens, as viewed from the object side. The defined arrangement of the phase plate and the associated shift of the real pupil into the air space between the first two lenses or groups of lenses, respectively, of the microscope objective allows a microscope objective, initially designed as a bright-field variant, to be redesigned as a phase contrast variant with relative ease.

摘要翻译： 具有至少四个透镜或透镜组的显微镜物镜，其可用于改善图像对比度。 根据本发明，从对象侧观察，与光轴同心对准的相位板可以集成到第一透镜和第二透镜之间的空间中并从其中取出。 相位板的限定布置以及分别在显微镜物镜的前两个透镜或透镜组之间的真实光瞳相关位移到空间中允许将最初被设计为亮场变体的显微镜物镜 相对容易地重新设计为相位差变体。

公开(公告)号：US20090284841A1

公开(公告)日：2009-11-19

申请号：US12299424

申请日：2007-04-26

申请人： Renhu Shi ,  Werner Kleinschmidt ,  Thomas Bocher

发明人： Renhu Shi ,  Werner Kleinschmidt ,  Thomas Bocher

IPC分类号： G02B21/02

CPC分类号： G02B21/02

摘要： The invention relates to a microscope objective with preferably anti-symmetric lenses or lens groups with an optical magnification of −100 and a visual field factor of 20.According to the invention the microscope objective consists of 9 lenses with 3 cemented elements, starting from the object side (left), a lens which is almost a hemisphere L1 with positive refractive power, a meniscus lens L2 with positive refractive power, a two-part cemented element G1 with positive refractive power, another two-art cemented element G2 with positive refractive power, a two-part cemented element G3 with negative refractive power, and finally a meniscus lens L9 with negative refractive power.By using cemented elements and lens pairings of the same construction, production costs can be reduced compared with methods of the prior art while image contrast is improved.

摘要翻译： 本发明涉及一种具有优选的反对称透镜或透镜组的显微镜物镜，其光学放大倍数为-100，视野因数为20.根据本发明，显微镜物镜由9个具有3个胶结元件的透镜组成，从 物体侧（左），具有正屈光力的几乎是半球L1的透镜，具有正屈光力的弯月透镜L2，具有正屈光力的两部分胶结元件G1，具有正折射率的另外两种胶合元件G2 功率为负屈光力的两部分胶结元件G3，最后是具有负屈光力的弯月透镜L9。 通过使用相同结构的胶结元件和透镜配对，与现有技术的方法相比，可以降低生产成本，同时改善图像对比度。

公开(公告)号：US07907348B2

公开(公告)日：2011-03-15

申请号：US12299424

申请日：2007-04-26

申请人： Renhu Shi ,  Werner Kleinschmidt ,  Thomas Bocher

发明人： Renhu Shi ,  Werner Kleinschmidt ,  Thomas Bocher

IPC分类号： G02B21/02

CPC分类号： G02B21/02

摘要： The invention relates to a microscope objective with preferably anti-symmetric lenses or lens groups with an optical magnification of −100 and a visual field factor of 20.According to the invention the microscope objective consists of 9 lenses with 3 cemented elements, starting from the object side (left), a lens which is almost a hemisphere L1 with positive refractive power, a meniscus lens L2 with positive refractive power, a two-part cemented element G1 with positive refractive power, another two-art cemented element G2 with positive refractive power, a two-part cemented element G3 with negative refractive power, and finally a meniscus lens L9 with negative refractive power.By using cemented elements and lens pairings of the same construction, production costs can be reduced compared with methods of the prior art while image contrast is improved.

摘要翻译： 本发明涉及一种具有优选的反对称透镜或透镜组的显微镜物镜，其光学放大倍数为-100，视野因数为20.根据本发明，显微镜物镜由9个具有3个胶结元件的透镜组成，从 物体侧（左），具有正屈光力的几乎是半球L1的透镜，具有正屈光力的弯月透镜L2，具有正屈光力的两部分胶合元件G1，具有正折射率的另外两部分胶结元件G2 功率为负屈光力的两部分胶结元件G3，最后是具有负屈光力的弯月透镜L9。 通过使用相同结构的胶结元件和透镜配对，与现有技术的方法相比，可以降低生产成本，同时改善图像对比度。

公开(公告)号：US20080106795A1

公开(公告)日：2008-05-08

申请号：US11979580

申请日：2007-11-06

申请人： Renhu Shi ,  Ingo Fahlbusch ,  Werner Kleinschmidt

发明人： Renhu Shi ,  Ingo Fahlbusch ,  Werner Kleinschmidt

IPC分类号： G02B21/02 ,  G02B9/00

CPC分类号： G02B21/33 ,  G02B27/0068

摘要： An immersion microscope objective includes a system of several optical lenses or lens groups between which air spaces are provided and an adjusting device for adapting the immersion microscope objective to different immersion mediums for correcting imaging errors when utilizing the immersion microscope objective in connection with a cover glass, which closes off a specimen holder, and/or for correcting longitudinal chromatic aberrations. The adjusting device is configured to change two air spaces and especially the air spaces (A1, A2) are linearly changeable.

摘要翻译： 浸没式显微镜物镜包括几个光学透镜或透镜组的系统，在该系统之间设有空气空间;以及调节装置，用于将浸没式显微镜物镜适用于不同的浸渍介质，以便在利用与玻璃罩相关的浸没显微镜物镜时校正成像误差 ，其封闭样品架，和/或用于校正纵向色差。 调整装置被配置为改变两个空气空间，特别是空气空间（A 1，A 2，2）可以线性地改变。

公开(公告)号：US07782539B2

公开(公告)日：2010-08-24

申请号：US11979580

申请日：2007-11-06

申请人： Renhu Shi ,  Ingo Fahlbusch ,  Werner Kleinschmidt

发明人： Renhu Shi ,  Ingo Fahlbusch ,  Werner Kleinschmidt

IPC分类号： G02B21/02 ,  G02B21/00

CPC分类号： G02B21/33 ,  G02B27/0068

摘要： An immersion microscope objective includes a system of several optical lenses or lens groups between which air spaces are provided and an adjusting device for adapting the immersion microscope objective to different immersion mediums for correcting imaging errors when utilizing the immersion microscope objective in connection with a cover glass, which closes off a specimen holder, and/or for correcting longitudinal chromatic aberrations. The adjusting device is configured to change two air spaces and especially the air spaces (A1, A2) are linearly changeable.

摘要翻译： 浸没式显微镜物镜包括几个光学透镜或透镜组的系统，在该系统之间设有空气空间;以及调节装置，用于将浸没式显微镜物镜适用于不同的浸渍介质，以便在利用与玻璃罩相关的浸没显微镜物镜时校正成像误差 ，其封闭样品架，和/或用于校正纵向色差。 调整装置被配置为改变两个空气空间，特别是空气空间（A1，A2）是线性可变的。

公开(公告)号：US20080024861A1

公开(公告)日：2008-01-31

申请号：US11828617

申请日：2007-07-26

申请人： EUGEN WEHNER ,  Joerg Schaffer ,  Werner Kleinschmidt

发明人： EUGEN WEHNER ,  Joerg Schaffer ,  Werner Kleinschmidt

IPC分类号： G02B21/26

CPC分类号： G02B21/28 ,  B01L7/00 ,  G02B21/30

摘要： The invention is directed to an arrangement for regulating the temperature of the sample space of a microscope, preferably for observing cells (live cell imaging) with an objective turret carrying objectives, a sample holder serving to receive a sample, a heating or cooling insert with an incubator hood for managing the temperature of the sample holder, and an objective heating element or objective cooling element. According to the invention, at least one structural component part which blocks the heating flow or cooling flow is provided between the objective heating element or objective cooling element and the objective turret.

摘要翻译： 本发明涉及一种用于调节显微镜样品空间温度的装置，优选用于观察携带物镜的目标转盘（活细胞成像），用于接收样品的样品架，加热或冷却插入物 用于管理样品保持器的温度的孵化器罩，以及客观加热元件或目标冷却元件。 根据本发明，在目标加热元件或目标冷却元件和物镜转台之间设置有阻挡加热流或冷却流的至少一个结构部件。

公开(公告)号：US08115164B2

公开(公告)日：2012-02-14

申请号：US12320599

申请日：2009-01-29

申请人： Ralf Netz ,  Wolfgang Bathe ,  Joerg Steinert ,  Werner Kleinschmidt ,  Ingo Fahlbusch ,  Michael Brehm

发明人： Ralf Netz ,  Wolfgang Bathe ,  Joerg Steinert ,  Werner Kleinschmidt ,  Ingo Fahlbusch ,  Michael Brehm

IPC分类号： G01D18/00

CPC分类号： G02B21/34 ,  G01M11/0264 ,  G02B21/002 ,  G02B27/32

摘要： A calibration device for managing a variety of performance tests and/or calibration tasks in a laser scanning microscope. The calibration device, which has focusing optics and a test structure arranged in the focal plane of the focusing optics, with structural elements detectable in reflected and/or transmitted light aligned to each other in a common mounting, can be switched into the microscope beam path in a laser scanning microscope, so that the pupil of the focusing optics coincides with the objective pupil of the laser scanning microscope or lies in a plane conjugated to it.

摘要翻译： 用于在激光扫描显微镜中管理各种性能测试和/或校准任务的校准装置。 具有聚焦光学元件和布置在聚焦光学器件的焦平面中的测试结构的校准装置可以被转换成显微镜光束路径，该结构元件可在反射和/或透射的光中可检测到，在共同安装中彼此对准 在激光扫描显微镜中，使得聚焦光学元件的瞳孔与激光扫描显微镜的客观瞳孔重合或位于与其共轭的平面中。

公开(公告)号：US07502165B2

公开(公告)日：2009-03-10

申请号：US11828617

申请日：2007-07-26

申请人： Eugen Wehner ,  Joerg Schaffer ,  Werner Kleinschmidt

发明人： Eugen Wehner ,  Joerg Schaffer ,  Werner Kleinschmidt

IPC分类号： G02B21/26

CPC分类号： G02B21/28 ,  B01L7/00 ,  G02B21/30

摘要： The invention is directed to an arrangement for regulating the temperature of the sample space of a microscope, preferably for observing cells (live cell imaging) with an objective turret carrying objectives, a sample holder serving to receive a sample, a heating or cooling insert with an incubator hood for managing the temperature of the sample holder, and an objective heating element or objective cooling element. According to the invention, at least one structural component part which blocks the heating flow or cooling flow is provided between the objective heating element or objective cooling element and the objective turret.

摘要翻译： 本发明涉及一种用于调节显微镜样品空间温度的装置，优选用于观察携带物镜的目标转盘（活细胞成像），用于接收样品的样品架，加热或冷却插入物 用于管理样品保持器的温度的孵化器罩，以及客观加热元件或目标冷却元件。 根据本发明，在目标加热元件或目标冷却元件和物镜转台之间设置有阻挡加热流或冷却流的至少一个结构部件。

公开(公告)号：US20130027768A1

公开(公告)日：2013-01-31

申请号：US13577246

申请日：2011-02-04

申请人： Ingo Fahlbusch ,  Werner Kleinschmidt ,  Heinrich Bunger ,  Peter Schnüll ,  Wolfgang Hartje ,  Georg Herbst

发明人： Ingo Fahlbusch ,  Werner Kleinschmidt ,  Heinrich Bunger ,  Peter Schnüll ,  Wolfgang Hartje ,  Georg Herbst

IPC分类号： G02B21/24

CPC分类号： G02B7/14 ,  G02B21/02

摘要： A device for attaching a first optical microscope component part to a second part includes an annular receptacle attached to the second part and an annual insertion part. The annular insertion part includes outside-conical retaining projections. The receptacle includes a base ring having a retaining collar with an inside cone tapering away from the base ring and in which a lateral opening is formed, through which the insertion part can be inserted in the receptacle such that it is located on a pre-locking position in which the annular openings overlap. The insertion part and the receptacle can be moved by reciprocal rotation from the pre-locking position into a locking position in which the outside-conical retaining projections of the insertion part are seated against the inside cone of the retaining collar and press the insertion part on the base ring, whereby the insertion part is locked to the receptacle.

摘要翻译： 用于将第一光学显微镜部件附接到第二部件的装置包括附接到第二部分的环形插座和年度插入部。 环形插入部分包括外锥形保持突起。 所述容器包括具有保持套环的基座环，所述保持套环具有与所述基座环成锥形的内锥体，并且其中形成有侧向开口，所述插入部件可以通过所述侧孔插入所述插座中，使得其位于预锁定 环形开口重叠的位置。 插入部分和插座可以通过往复旋转从预锁定位置移动到锁定位置，其中插入部分的外锥形保持突起抵靠保持环的内锥体并将插入部分按压在 基座环，由此插入部分被锁定到容器。