公开(公告)号：US09881710B2

公开(公告)日：2018-01-30

申请号：US13260424

申请日：2010-03-19

申请人： Ewald Roessl ,  Thomas Koehler

发明人： Ewald Roessl ,  Thomas Koehler

IPC分类号： G21K1/06 ,  G02B27/52

CPC分类号： G21K1/06 ,  G02B27/52 ,  G21K2207/005

摘要： An achromatic phase-contrast imaging apparatus for examining an object of interest is provided which comprises two different phase gratings which have different pitches. Thus, the imaging apparatus yields phase-contrast information for two different energies. Thus, phase-information over a wider energy band can be used.

公开(公告)号：US08203788B2

公开(公告)日：2012-06-19

申请号：US12677650

申请日：2008-09-17

申请人： Jesper Glückstad

发明人： Jesper Glückstad

IPC分类号： G02B5/08 ,  G02F1/01

CPC分类号： G02B27/0927 ,  G02B27/0988 ,  G02B27/46 ,  G02B27/52

摘要： The present invention relates to an electromagnetic beam converter and a method for conversion of an input beam of electromagnetic radiation having a bell shaped intensity profile a(x,y) into an output beam having a prescribed target intensity profile I(x′,y′) based on a further development of the generalized phase contrast method.

摘要翻译： 本发明涉及电磁波束转换器和用于将具有钟形强度分布a（x，y）的电磁辐射的输入光束转换成具有规定的目标强度分布I（x'，y'）的输出光束的方法， ）基于广义相位法的进一步发展。

公开(公告)号：US07920673B2

公开(公告)日：2011-04-05

申请号：US12261267

申请日：2008-10-30

申请人： Richard C. Lanza ,  Berthold K.P. Horn ,  Antonio L. Damato

发明人： Richard C. Lanza ,  Berthold K.P. Horn ,  Antonio L. Damato

IPC分类号： G01N23/04

CPC分类号： G02B27/52 ,  G21K2207/005

摘要： Phase-contrast imaging is performed by directing radiation from a plurality of pinhole sources through a phase object to be imaged, wherein the phase object includes a first composition that produces a phase shift in the radiation relative to radiation passing through a second composition in the phase object and detecting a phase-contrast image of the radiation after it passes through the phase object. The phase-contrast image is then decoded to generate an image of the phase object in which the first composition is distinguished from the second composition.

摘要翻译： 通过将来自多个针孔源的辐射引导通过待成像的相位物体来执行相位对比成像，其中相位对象包括第一组合物，该第一组合物相对于穿过第二组合物的相位的辐射产生相移 对象并检测辐射经过相位物体后的相位对比度图像。 然后对相位对比图像进行解码，以生成其中第一组合与第二组合物不同的相位对象的图像。

公开(公告)号：US07880820B2

公开(公告)日：2011-02-01

申请号：US12795974

申请日：2010-06-08

申请人： Chandra S. Yelleswarapu ,  Sri Rajeasekhar Kothapalli ,  D. V. Gopal L. N. Rao

发明人： Chandra S. Yelleswarapu ,  Sri Rajeasekhar Kothapalli ,  D. V. Gopal L. N. Rao

IPC分类号： G02F1/1335

CPC分类号： G02B21/14 ,  G02B27/52 ,  G02F1/132 ,  G02F1/13725

摘要： An assembly for converting a microscope into a phase contrast microscope includes a first optical Fourier element that Fourier transforms light from a coherent light source, a cell in the Fourier plane arranged to receive light from the first optical Fourier element, a second optical Fourier element arranged to receive light from the cell and inversely Fourier transform the received light to provide an image, an image sensor that detects the image and generates an electronic representation of the image, and an adaptor capable of coupling the first and second Fourier elements, the cell, and the image sensor to the microscope such that the first Fourier element Fourier transforms light collected by the microscope objective. The cell includes liquid crystal molecules having a phase transition temperature, wherein at temperatures exceeding the phase transition temperature, light transmitting through the liquid crystal molecules obtains a different phase than light transmitting through the liquid crystal molecules at temperatures below the phase transition temperature.

摘要翻译： 用于将显微镜转换成相差显微镜的组件包括傅里叶变换来自相干光源的光的第一光学傅里叶变换元件，布置成从第一光学傅里叶变换元件接收光的傅立叶平面中的单元，布置成 从单元接收光并对接收的光进行逆傅里叶变换以提供图像;图像传感器，其检测图像并生成图像的电子表示;以及适配器，其能够耦合第一和第二傅立叶元件，单元， 和图像传感器到显微镜，使得第一傅里叶元素傅里叶变换由显微镜物镜收集的光。 电池包括具有相变温度的液晶分子，其中在超过相变温度的温度下，透过液晶分子的光获得与低于相变温度的温度下透过液晶分子的光的不同相位。

公开(公告)号：US20090310206A1

公开(公告)日：2009-12-17

申请号：US12305264

申请日：2007-06-18

申请人： Jesper Gluckstad

发明人： Jesper Gluckstad

IPC分类号： G02B27/52

CPC分类号： G02B27/52 ,  G02B21/32 ,  G06E3/00 ,  Y10S359/90

摘要： A method and system for synthesizing controllable light beams includes a spatially modulated light source that generates electromagnetic radiation with a set of replicas of a predetermined symbol, s, positioned at desired positions (xs, ys) in an object plane o(x, y) intersecting, preferably perpendicular to, the direction of propagation of the electromagnetic radiation, and having spatial amplitudes a(x-xs, y-ys), spatial phases φ(x-xs, y-ys), and spatial polarisation vectors p(x-xs, y-ys), a Fourier transforming lens for Fourier transforming the electromagnetic radiation, a first spatial light modulator for phase shifting the transformed electromagnetic radiation with the phase −Φ(u, v) of S*, S* the complex conjugate of the transformed symbol, a Fourier transforming lens for Inverse Fourier transforming the spatially modulated radiation, a set of light beams are formed propagating through the inverse Fourier plane (x′, y′) at desired positions (x′s, y′s), and a controller for controlling the position of a replica of the symbol, for movement of the light beam.

摘要翻译： 用于合成可控光束的方法和系统包括空间调制的光源，其产生电磁辐射，其具有定位在物平面o（x，y）中的期望位置（xs，y）处的预定符号s的一组副本， 相交，优选垂直于电磁辐射的传播方向，并且具有空间振幅a（x-xs，y-ys），空间相位phi（x-xs，y-ys）和空间极化矢量p（x -xs，y-ys），用于对电磁辐射进行傅里叶变换的傅立叶变换透镜，用S *，S *的相位-Phi（u，v）将复合电磁辐射相移的第一空间光调制器 的变换符号的傅立叶变换透镜，用于对空间调制的辐射进行逆傅立叶变换，形成一组光束，其在期望的位置（x，y）处通过傅立叶逆傅立叶平面（x'，y'）传播，并且控制器 为公司 控制符号的副本的位置，用于光束的移动。

公开(公告)号：US20090097110A1

公开(公告)日：2009-04-16

申请号：US12335821

申请日：2008-12-16

申请人： PAUL C. GOODWIN

发明人： PAUL C. GOODWIN

IPC分类号： G02B21/06

CPC分类号： G02B21/0092 ,  G02B21/14 ,  G02B21/16 ,  G02B27/52

摘要： A system and method of generating and acquiring phase contrast microscope images while minimizing interference with the intensity and optical quality of other microscopy modalities employing polarization and attenuation strategies for phase microscopy applications. A plane polarizing objective phase ring may be used in conjunction with a phase microscopy apparatus. Attenuated light may be controlled such that transparency may be selectively provided with respect to light in a predetermined plane. Illumination outside of the predetermined plane may be selected for phase microscopy applications. Accordingly, a polarizing objective phase ring effective for enabling polarized phase microscopy may reduce interfere with normal usage of the microscope for other applications such as, for example, fluorescence microscopy.

摘要翻译： 一种生成和获取相位显微镜图像的系统和方法，同时最小化使用相位显微镜应用的极化和衰减策略的其他显微镜模式的强度和光学质量的干扰。 平面偏振目标相位环可以与相位显微镜装置结合使用。 可以控制衰减的光，使得可以相对于预定平面中的光选择性地提供透明度。 对于相位显微镜应用，可以选择预定平面外的照明。 因此，对于允许极化相位显微镜有效的偏振目标相位环可以减少对于其它应用例如荧光显微镜的显微镜的正常使用的干扰。

公开(公告)号：US20080174860A1

公开(公告)日：2008-07-24

申请号：US11935910

申请日：2007-11-06

申请人： Chandra S. YELLESWARAPU ,  Sri R. KOTHAPALLI ,  D.V.G.L.N. RAO

发明人： Chandra S. YELLESWARAPU ,  Sri R. KOTHAPALLI ,  D.V.G.L.N. RAO

IPC分类号： G02B21/14

CPC分类号： G02B21/14 ,  G02B27/52 ,  G02F1/132 ,  G02F1/13725

摘要： Under one aspect, a phase contrast imaging system includes a coherent light source emitting a coherent beam directed toward a sample area; a lens arranged to collect at least part of the beam from the sample area; an element Fourier transforming the collected beam in a Fourier plane; a liquid crystal cell in the Fourier plane that transmits at least part of the transformed beam, wherein the cell includes liquid crystal molecules having a phase transition temperature, and wherein at temperatures exceeding the phase transition temperature, light transmitted through the liquid crystal molecules obtains a different phase than light transmitted through the liquid crystal molecules obtains at temperatures below the phase transition temperature; and an element inversely Fourier transforming the transmitted beam to provide an image. Part of the transformed beam has an intensity sufficient to heat a portion of the liquid crystal molecules above the phase transition temperature.

摘要翻译： 在一个方面，相位对比成像系统包括发射朝向样本区域的相干光束的相干光源; 透镜，布置成从样品区域收集至少一部分光束; 在傅立叶平面中傅里叶变换收集的光束的元素; 透射至少部分变换光束的傅立叶平面中的液晶单元，其中，所述单元包括具有相变温度的液晶分子，并且其中在超过相变温度的温度下，透过液晶分子的光获得 不同于透过液晶分子的光在低于相变温度的温度下获得; 以及将透射光束逆傅立叶变换以提供图像的元素。 变换束的一部分具有足以将一部分液晶分子加热到相转变温度以上的强度。

公开(公告)号：US20060285104A1

公开(公告)日：2006-12-21

申请号：US11454644

申请日：2006-06-15

申请人： Meagan Walsh

发明人： Meagan Walsh

IPC分类号： G01N33/48

CPC分类号： G02B21/14 ,  G01N2015/0073 ,  G01N2015/008 ,  G01N2015/0084 ,  G01N2015/0092 ,  G01N2015/1486 ,  G01N2015/1493 ,  G02B27/52

摘要： 13 An apparatus for testing and determining a biological function based upon blood samples comprising a specimen holder for holding a blood sample; a light on the specimen; a molecular imager for viewing the specimens; and a software program for determining a medical problem based upon an aspect of the blood sample specimen.

摘要翻译： 13，一种用于测试和确定基于血液样本的生物学功能的装置，包括用于保持血液样本的样本保持器; 样品上的光; 用于观察标本的分子成像仪; 以及用于基于血液样本样本的方面确定医疗问题的软件程序。

公开(公告)号：US20050219704A1

公开(公告)日：2005-10-06

申请号：US11129363

申请日：2005-05-16

申请人： Masataka Shirasaki ,  Simon Cao

发明人： Masataka Shirasaki ,  Simon Cao

IPC分类号： G02B5/10 ,  G02B6/34 ,  G02B27/00 ,  G02B27/14 ,  G02B27/52 ,  H04B10/18

CPC分类号： G02B27/144 ,  G02B6/29311 ,  G02B6/29358 ,  G02B6/29361 ,  G02B6/29392 ,  G02B6/29394 ,  G02B6/29395 ,  G02B27/0087 ,  G02B27/1006 ,  G02B27/106 ,  G02B27/1073 ,  G02B27/1086 ,  G02B27/126 ,  G02B27/145 ,  G02B27/148 ,  G02B27/52 ,  H04B10/25133

摘要： An optical apparatus for producing chromatic dispersion. The apparatus includes a virtually imaged phased array (VIPA) generator, a mirror and a lens. The VIPA generator receives an input light at a respective wavelength and produces a corresponding collimated output light traveling from the VIPA generator in a direction determined by the wavelength of the input light, the output light thereby being spatially distinguishable from an output light produced for an input light at a different wavelength. The mirror has a cone shape, or a modified cone shape. The lens focuses the output light traveling from the VIPA generator onto the mirror so that the mirror reflects the output light. The reflected light is directed by the lens back to the VIPA generator. In this manner, the apparatus provides chromatic dispersion to the input light. The modified cone shape of the mirror can be designed so that the apparatus provides a uniform chromatic dispersion to light in the same channel of a wavelength division multiplexed light. The mirror can be moved in a direction perpendicular to an angular dispersion direction of the VIPA generator, to change the amount of chromatic dispersion provided to the input light.

摘要翻译： 一种用于产生色散的光学装置。 该装置包括虚拟成像的相控阵（VIPA）发生器，反射镜和透镜。 VIPA发生器接收相应波长的输入光，并产生从VIPA发生器沿由输入光的波长确定的方向行进的对准的准直输出光，从而与输入光产生的输出光在空间上区别开 在不同波长的光。 镜子有一个锥形或一个改锥形。 透镜将从VIPA发生器传播的输出光聚焦到镜子上，使镜子反射出输出光。 反射光被透镜引导回到VIPA发生器。 以这种方式，该装置向输入光提供色散。 反射镜的修改锥形可以被设计成使得该装置对波分复用光的相同通道中的光提供均匀的色散。 反射镜可以在与VIPA发生器的角度分散方向垂直的方向上移动，以改变提供给输入光的色散量。

公开(公告)号：US20040036978A1

公开(公告)日：2004-02-26

申请号：US10223966

申请日：2002-08-20

发明人： Sarma N. Gullapalli

IPC分类号： G02B027/14 ,  G02B027/10

CPC分类号： G02B27/48 ,  G02B27/52

摘要： The small field-of-view (FOV) limitation of current coherent beam combiner technology is overcome, enabling beam combining over significantly larger fields of view. The system includes an input to receive an input wavefront, a local oscillator to generate a reference wavefront, and an optical combiner such as a beam splitter to combine the input wavefront and the reference wavefront to produce an output wavefront which is received by a detector. According to the invention, an optical element is supported to receive the reference wavefront and generate, in effect, a plurality of local oscillator point sources which provide a set of wavefronts that cover the required wider FOV. In the preferred embodiment, the optical element is a diffuser, and may optionally include a mechanism for rotating the diffuser to reduce speckle. In an alternative embodiment the optical element is a lenslet array. The spacing of the lenslets in the array is preferably such that the angle subtended by centers of two adjacent lenslets as seen from the center of the system's collimating lens or mirror is less than 0.83 null/D, where null is the wavelength of the radiation, and D is the aperture diameter. This invention finds utility in any application which uses coherent beam combining, including optical communication systems, laser radar systems, and other fields of endeavor.

摘要翻译： 克服了当前相干光束组合器技术的小视野（FOV）限制，使得能够在明显更大的视场上进行光束组合。 该系统包括用于接收输入波前的输入端，用于产生参考波前的本地振荡器以及诸如波束分离器的光合成器以组合输入波阵面和参考波阵面以产生由检测器接收的输出波前。 根据本发明，支持光学元件以接收参考波阵面并且实际上产生多个本地振荡器点源，其提供覆盖所需更宽的FOV的一组波前。 在优选实施例中，光学元件是漫射器，并且可以可选地包括用于旋转扩散器以减少斑点的机构。 在替代实施例中，光学元件是小透镜阵列。 阵列中的小透镜的间距优选地使得从系统的准直透镜或反射镜的中心看到的两个相邻小透镜的中心对向的角度小于0.83λ/ D，其中λ是辐射的波长， D为孔直径。 本发明可用于使用相干光束组合的任何应用，包括光通信系统，激光雷达系统和其它领域的工作。