公开(公告)号：US20180327817A1

公开(公告)日：2018-11-15

申请号：US15978333

申请日：2018-05-14

申请人： Rheonix, Inc.

发明人： F. Morgan Wallace

IPC分类号： C12Q1/689 ,  C12Q1/04 ,  C12Q1/6874 ,  C12Q1/6837 ,  G06K9/62

CPC分类号： C12Q1/689 ,  C12Q1/04 ,  C12Q1/6816 ,  C12Q1/6827 ,  C12Q1/6837 ,  C12Q1/6874 ,  C12Q2600/156 ,  G06K9/6227 ,  G06K9/6255 ,  G06K9/6276 ,  G06K9/6292 ,  C12Q2565/50

摘要： A system and method for strain typing without need for isolation in pure form and subsequent longitudinal strain tracking. The method includes the steps of locating one or more genetic regions present in a target. The genetic regions contain genetic loci that vary among two or more variants (i.e., strains) of the target. A device detects a unique sequence of each of the genetic loci. After a sample of biological material having the genetic loci is obtained, the device generates an amplicon for the genetic regions present in the target. The amplicons are hybridized to complimentary probes, resulting in hybridized probes and non-hybridized probes, which are detected. The detected hybridized probes are assigned an identifier. The device transforms the identifiers into a pattern. The pattern is recorded and compared to one or more other patterns recorded to determine if the pattern is different from the one or more other patterns.