Designed protein pores as components for biosensors
    4.
    发明授权
    Designed protein pores as components for biosensors 有权
    设计蛋白质孔作为生物传感器的组成部分

    公开(公告)号:US06824659B2

    公开(公告)日:2004-11-30

    申请号:US09784985

    申请日:2001-02-15

    IPC分类号: G01N27327

    CPC分类号: C07K14/31 G01N33/48721

    摘要: A mutant staphylococcal alpha hemolysin polypeptide containing a heterologous analyte-binding amino acid which assembles into an analyte-responsive heptameric pore assembly in the presence of a wild type staphylococcal alpha hemolysin polypeptide, digital biosensors, and methods of detecting, identifying, and quantifying analytes are described.

    摘要翻译: 在野生型葡萄球菌α溶血素多肽,数字生物传感器以及检测,鉴定和定量分析物的方法中,含有异源分析物结合氨基酸的突变型葡萄球菌α溶血素多肽组装成分析物响应性七聚体孔组件, 描述。