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公开(公告)号：US08852199B2
公开(公告)日：2014-10-07
申请号：US12852260
申请日：2010-08-06
CPC分类号： A61B17/00491 , A61B42/20
摘要： A bone adhesive application device has a pliable structure with an application surface upon which a bone adhesive may be applied. The application surface has a surface energy substantially equal to or less than a surface energy of the bone adhesive to reduce adhesion between the bone adhesive and the bone adhesive application device. The bone adhesive application device may be included in a kit for repairing bone defects having a bone adhesive formed from a reactive biocompatible polyurethane material. The bone adhesive may be applied to a bone defect by positioning the pliable structure over at least a portion of the bone defect, delivering the bone adhesive to the bone defect and removing the pliable structure from the bone adhesive.
摘要翻译： 骨粘合剂施用装置具有柔韧的结构，其上具有施用表面，可以在其上施用骨粘合剂。 施用表面具有基本上等于或小于骨粘合剂的表面能的表面能，以减少骨粘合剂和骨粘合剂施加装置之间的粘合。 骨粘合剂施加装置可以包括在用于修复具有由反应性生物相容性聚氨酯材料形成的骨粘合剂的骨缺损的试剂盒中。 通过将柔韧结构定位在骨缺损的至少一部分上，将骨粘合剂施加到骨缺损，将骨粘合剂输送到骨缺损并从骨粘合剂去除柔韧结构。
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公开(公告)号：US20120035610A1
公开(公告)日：2012-02-09
申请号：US12852260
申请日：2010-08-06
IPC分类号： A61B17/58
CPC分类号： A61B17/00491 , A61B42/20
摘要： A bone adhesive application device has a pliable structure with an application surface upon which a bone adhesive may be applied. The application surface has a surface energy substantially equal to or less than a surface energy of the bone adhesive to reduce adhesion between the bone adhesive and the bone adhesive application device. The bone adhesive application device may be included in a kit for repairing bone defects having a bone adhesive formed from a reactive biocompatible polyurethane material. The bone adhesive may be applied to a bone defect by positioning the pliable structure over at least a portion of the bone defect, delivering the bone adhesive to the bone defect and removing the pliable structure from the bone adhesive.
摘要翻译： 骨粘合剂施用装置具有柔韧的结构，其上具有施用表面，可以在其上施用骨粘合剂。 施用表面具有基本上等于或小于骨粘合剂的表面能的表面能，以减少骨粘合剂和骨粘合剂施加装置之间的粘合。 骨粘合剂施加装置可以包括在用于修复具有由反应性生物相容性聚氨酯材料形成的骨粘合剂的骨缺损的试剂盒中。 通过将柔韧结构定位在骨缺损的至少一部分上，将骨粘合剂施加到骨缺损，将骨粘合剂输送到骨缺损并从骨粘合剂去除柔韧结构。
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公开(公告)号：US20110012280A1
公开(公告)日：2011-01-20
申请号：US12502635
申请日：2009-07-14
IPC分类号： B29C67/20
CPC分类号： B29C44/04 , A61B5/064 , A61B90/39 , A61B2090/3945 , A61B2090/3983 , A61B2090/3987 , A61B2090/3991 , A61B2090/3995 , A61F2/442 , A61F2/4465 , A61F2/447 , A61F9/0136 , A61F2002/30006 , A61F2002/30011 , A61F2002/30056 , A61F2002/3008 , A61F2002/30448 , A61F2002/30594 , A61F2002/30617 , A61F2002/30619 , A61F2002/30772 , A61F2002/30774 , A61F2002/30795 , A61F2002/30797 , A61F2002/30904 , A61F2002/3093 , A61F2002/30957 , A61F2002/30971 , A61F2002/3266 , A61F2002/4629 , A61F2220/005 , A61F2250/0015 , A61F2250/0023 , A61F2250/0032 , A61F2250/0096 , A61F2250/0097 , A61F2250/0098 , A61F2310/00017 , A61F2310/00023 , B29C44/1214 , B29C44/3403
摘要： A multi-density polymeric interbody spacer formed from biocompatible material for osteoconductivity includes multiple density regions of different porosity to provide both strength and osteoconductivity. An interface region is formed between the density regions to provide both direct adhesion and mechanical interlocking between the different density regions to increase the strength of the multi-density polymeric interbody spacer. A method for forming the multi-density polymeric interbody spacer includes curing a first density region to achieve a first target porosity. A second density region may then be molded to the first density region to achieve a second target porosity. A portion of the second density region partially flows into pores of the first density region, providing direct adhesion and mechanical interlocking between the first and second density regions.
摘要翻译： 由用于骨传导性的生物相容性材料形成的多密度聚合物体间间隔物包括具有不同孔隙率的多个密度区域以提供强度和骨传导性。 在密度区域之间形成界面区域，以提供不同密度区域之间的直接粘合和机械互锁，以增加多密度聚合物体间间隔物的强度。 用于形成多密度聚合物体间间隔物的方法包括固化第一密度区域以实现第一目标孔隙度。 然后可以将第二密度区域模制到第一密度区域以实现第二目标孔隙度。 第二密度区域的一部分部分地流入第一密度区域的孔，从而提供第一和第二密度区域之间的直接粘合和机械互锁。
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公开(公告)号：US20110015743A1
公开(公告)日：2011-01-20
申请号：US12502597
申请日：2009-07-14
IPC分类号： A61F2/44
CPC分类号： A61F2/4455 , A61F2002/30006 , A61F2002/30011 , A61F2002/3008 , A61F2002/30224 , A61F2230/0069 , A61F2250/0015 , A61F2250/0023 , A61F2250/0098 , A61F2310/0097
摘要： A multi-density polymeric interbody spacer formed from biocompatible material for osteoconductivity includes multiple density regions of different porosity to provide both strength and osteoconductivity. An interface region is formed between the density regions to provide both direct adhesion and mechanical interlocking between the different density regions to increase the strength of the multi-density polymeric interbody spacer. A method for forming the multi-density polymeric interbody spacer includes curing a first density region to achieve a first target porosity. A second density region may then be molded to the first density region to achieve a second target porosity. A portion of the second density region partially flows into pores of the first density region, providing direct adhesion and mechanical interlocking between the first and second density regions.
摘要翻译： 由用于骨传导性的生物相容性材料形成的多密度聚合物体间间隔物包括具有不同孔隙率的多个密度区域以提供强度和骨传导性。 在密度区域之间形成界面区域，以提供不同密度区域之间的直接粘合和机械互锁，以增加多密度聚合物体间间隔物的强度。 用于形成多密度聚合物体间间隔物的方法包括固化第一密度区域以实现第一目标孔隙度。 然后可以将第二密度区域模制到第一密度区域以实现第二目标孔隙度。 第二密度区域的一部分部分地流入第一密度区域的孔，从而提供第一和第二密度区域之间的直接粘合和机械互锁。
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公开(公告)号：US20060200043A1
公开(公告)日：2006-09-07
申请号：US11069668
申请日：2005-03-01
IPC分类号： A61B10/00
CPC分类号： A61B10/0045 , A61B10/0038 , A61B10/0051 , A61B2010/0074
摘要： Sample collection for the Pap smear sample is critical for accurate diagnosis. Improper sample collection, poor sampling, and/or cell preservation can render a Pap smear unsatisfactory for evaluation, requiring a repeat smear collection. If the Pap smear does not contain appropriate representative cells from the transformation zone and endocervical canal, the ability of the test to detect disease is very low. Likewise, if the preservation of the sample is compromised, the screener's ability to recognize abnormal cells is greatly diminished. It is generally understood that cervical samples should be harvested by a two-stage technique, which includes sampling of the endocervical canal with a cytobrush and obtaining a sample from the transformation zone with a spatula. The use of either the cytobrush or the spatula alone may be adequate but not as effective as the two-stage technique. Both the Cervex Brush and REG;(Unimar, Inc.) and the Accellon Combi & REG;(Medscand AB) are two collection devices which combine the action of the cytobrush and spatula, thus permitting broader sampling with a one stage technique. The standard method of transferring cervical cells from the collection device or complete transfer of the collection device into the liquid collection vial is often challenging. These challenges include but are not limited to: 1-spilling the sample, 2-dispersing the medium collection such that air born body secretions could contact unprotected health care workers, 3-missing the collection container and contaminating the sample. It is the goal of the current device embodiment to provide a simple and consistent method of transferring the entire collection specimen into the collection container to maximize cell collection while minimizing challenges of head disengagement. Such devices are not limited to the cervical cell cytology collection markets but extend to all cell collection methods were the entire sample is suspended in a liquid or similar medium. Such samples include oral cavity collections (throat swabs, vaginal cavity collections (STDs, pregnancy test), urethral cavity collections (male STDs) fornex collections (Alaph fetal protein), and rectal collections as well as open procedures requiring cell sampling.
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