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公开(公告)号：US20060258617A1
公开(公告)日：2006-11-16
申请号：US11460392
申请日：2006-07-27
申请人： Robert Lyon , Chin-Ming Chang , Joan-En Chang-Lin , James Chang , Orest Olejnik
发明人： Robert Lyon , Chin-Ming Chang , Joan-En Chang-Lin , James Chang , Orest Olejnik
IPC分类号： A61K31/724 , A61K31/717 , A61K31/573
CPC分类号： A61K9/0014 , A61K9/0048 , A61K31/57 , A61K31/573 , A61K31/724 , A61K47/38 , A61K47/40
摘要： Disclosed herein are methods of delivering drugs or therapeutically active agents to the back of the eye via topical administration of compositions comprising cyclodextrin derivatives. Compositions related thereto are also disclosed herein.
摘要翻译： 本文公开了通过局部施用包含环糊精衍生物的组合物将药物或治疗活性剂递送至眼睛后部的方法。 本文还公开了与其相关的组合物。
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公开(公告)号：US20050234018A1
公开(公告)日：2005-10-20
申请号：US10826843
申请日：2004-04-15
申请人： Robert Lyons , Chin-Ming Chang , Joan-En Chang-Lin , James Chang , Orest Olejnik
发明人： Robert Lyons , Chin-Ming Chang , Joan-En Chang-Lin , James Chang , Orest Olejnik
IPC分类号： A61K9/00 , A61K31/00 , A61K31/57 , A61K31/573 , A61K31/724 , A61K47/38 , A61K47/40
CPC分类号： A61K9/0014 , A61K9/0048 , A61K31/57 , A61K31/573 , A61K31/724 , A61K47/38 , A61K47/40
摘要： Disclosed herein are methods of delivering drugs or therapeutically active agents to the back of the eye via topical administration of compositions comprising cyclodextrin derivatives. Compositions related thereto are also disclosed herein.
摘要翻译： 本文公开了通过局部施用包含环糊精衍生物的组合物将药物或治疗活性剂递送至眼睛后部的方法。 本文还公开了与其相关的组合物。
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公开(公告)号：US20060211770A1
公开(公告)日：2006-09-21
申请号：US11083261
申请日：2005-03-16
申请人： Chin-Ming Chang , James Chang , Rhett Schiffman , R. Jordan , Joan-En Chang-Lin
发明人： Chin-Ming Chang , James Chang , Rhett Schiffman , R. Jordan , Joan-En Chang-Lin
IPC分类号： A61K31/557 , A61K31/14
CPC分类号： A61K31/5575 , A01N33/12 , A61K9/0048 , A61K31/14 , A61K31/165 , A61K31/557 , A61K47/02 , A61K47/12
摘要： A composition comprising from 0.005% to 0.02% bimatoprost by weight and from 100 ppm to 250 ppm benzalkonium chloride, wherein said composition is an aqueous liquid which is formulated for ophthalmic administration is disclosed herein. A method which is useful in treating glaucoma or ocular hypertension related thereto is also disclosed herein.
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公开(公告)号：US20080107719A1
公开(公告)日：2008-05-08
申请号：US11594517
申请日：2006-11-08
CPC分类号： A61K9/7084 , A61K9/0009 , A61K47/08 , A61K47/16 , A61K47/26 , A61N1/044 , A61N1/0444 , A61N1/0448 , A61N1/327
摘要： A transdermal drug delivery system includes a drug source, an adhesive for applying the system to a skin surface, a penetration enhancer for enhancing penetration of the drug into the skin surface, an energy source and a contact for conveying energy from said energy source through said adhesive and the penetrating enhancer.
摘要翻译： 透皮药物递送系统包括药物源，用于将系统施用于皮肤表面的粘合剂，用于增强药物渗入皮肤表面的渗透促进剂，能量源和用于将能量从所述能量源传递通过所述皮肤表面的接触件 粘合剂和渗透增强剂。
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公开(公告)号：US20120316243A1
公开(公告)日：2012-12-13
申请号：US13551362
申请日：2012-07-17
CPC分类号： A61K31/5575 , A61K9/0048 , A61K9/08 , A61K31/14 , A61K31/164 , A61K31/165 , A61K47/02 , A61K47/183 , A61K47/186 , A61K2300/00
摘要： A composition comprising from 0.005% to 0.02% bimatoprost by weight and from 100 ppm to 250 ppm benzalkonium chloride, wherein said composition is an aqueous liquid which is formulated for ophthalmic administration is disclosed herein. A method which is useful in treating glaucoma or ocular hypertension related thereto is also disclosed herein.
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公开(公告)号：US20090149546A1
公开(公告)日：2009-06-11
申请号：US12351383
申请日：2009-01-09
IPC分类号： A61K31/165
CPC分类号： A61K31/5575 , A01N33/12 , A61K9/0048 , A61K31/14 , A61K31/165 , A61K31/557 , A61K47/02 , A61K47/12
摘要： A composition comprising from 0.005% to 0.02% bimatoprost by weight and from 100 ppm to 250 ppm benzalkonium chloride, wherein said composition is an aqueous liquid which is formulated for ophthalmic administration is disclosed herein.A method which is useful in treating glaucoma or ocular hypertension related thereto is also disclosed herein.
摘要翻译： 本文公开了包含0.005％至0.02％的比马前列素和100ppm至250ppm苯扎氯铵的组合物，其中所述组合物是配制用于眼部给药的水性液体。 本文还公开了可用于治疗与其有关的青光眼或高眼压症的方法。
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公开(公告)号：US09241918B2
公开(公告)日：2016-01-26
申请号：US13254543
申请日：2010-03-04
IPC分类号： A61K31/19 , A61K31/215 , A61K31/164 , A61K9/00 , A61K9/08 , A61K31/14 , A61K31/5575 , A61K47/18 , A61K31/165
CPC分类号： A61K31/5575 , A61K9/0048 , A61K9/08 , A61K31/14 , A61K31/164 , A61K31/165 , A61K47/02 , A61K47/183 , A61K47/186 , A61K2300/00
摘要： A composition comprising from 0.005% to 0.02% bimatoprost by weight and from 100 ppm to 250 ppm benzalkonium chloride, wherein said composition is an aqueous liquid which is formulated for ophthalmic administration is disclosed herein. A method which is useful in treating glaucoma or ocular hypertension related thereto is also disclosed herein.
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公开(公告)号：US08309605B2
公开(公告)日：2012-11-13
申请号：US12965514
申请日：2010-12-10
IPC分类号： A61K31/19 , A61K31/215
CPC分类号： A61K31/5575 , A01N33/12 , A61K9/0048 , A61K31/14 , A61K31/165 , A61K31/557 , A61K47/02 , A61K47/12
摘要： A composition comprising from 0.005% to 0.02% bimatoprost by weight and from 100 ppm to 250 ppm benzalkonium chloride, wherein said composition is an aqueous liquid which is formulated for ophthalmic administration is disclosed herein.A method which is useful in treating glaucoma or ocular hypertension related thereto is also disclosed herein.
摘要翻译： 本文公开了包含0.005％至0.02％的比马前列素和100ppm至250ppm苯扎氯铵的组合物，其中所述组合物是配制用于眼部给药的水性液体。 本文还公开了可用于治疗与其有关的青光眼或高眼压症的方法。
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公开(公告)号：US20120142783A1
公开(公告)日：2012-06-07
申请号：US13370574
申请日：2012-02-10
IPC分类号： A61K31/165 , A61P27/02 , A61P27/06
CPC分类号： A61K31/5575 , A01N33/12 , A61K9/0048 , A61K31/14 , A61K31/165 , A61K31/557 , A61K47/02 , A61K47/12
摘要： A composition comprising from 0.005% to 0.02% bimatoprost by weight and from 100 ppm to 250 ppm benzalkonium chloride, wherein said composition is an aqueous liquid which is formulated for ophthalmic administration is disclosed herein.A method which is useful in treating glaucoma or ocular hypertension related thereto is also disclosed herein.
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公开(公告)号：US08524777B2
公开(公告)日：2013-09-03
申请号：US13551379
申请日：2012-07-17
IPC分类号： A61K31/14 , A61K31/557 , A61K31/5575
CPC分类号： A61K31/5575 , A61K9/0048 , A61K9/08 , A61K31/14 , A61K31/164 , A61K31/165 , A61K47/02 , A61K47/183 , A61K47/186 , A61K2300/00
摘要： A composition comprising from 0.005% to 0.02% bimatoprost by weight and from 100 ppm to 250 ppm benzalkonium chloride, wherein said composition is an aqueous liquid which is formulated for ophthalmic administration is disclosed herein. A method which is useful in treating glaucoma or ocular hypertension related thereto is also disclosed herein.
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