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    Collagen device and method of preparing the same
    1.
    发明申请
    Collagen device and method of preparing the same 审中-公开
    胶原装置及其制备方法

    公开(公告)号：US20050175659A1

    公开(公告)日：2005-08-11

    申请号：US10955835

    申请日：2004-09-30

    申请人： Laurel Macomber ,  Robert Sommerich ,  Vivek Shenoy

    发明人： Laurel Macomber ,  Robert Sommerich ,  Vivek Shenoy

    IPC分类号： A61L27/24 ,  A61L27/56 ,  A61L31/04 ,  A61L31/14 ,  A61K38/17 ,  A61F2/00

    CPC分类号： A61L27/56 ,  A61L27/24

    摘要： A collagen device is prepared by mixing collagen with purified water for a period of time sufficient to form a mixture. The pH of the mixture is adjusted to a pH level sufficient to substantially solubilize the collagen. A first predetermined amount of the mixture is placed into a container. The mixture is subject to a lyophilizing process and formed into a collagen device. The collagen device is also cross-linked. The collagen device has a plurality of pores wherein a majority of the pores have a diameter of less than 10 μm. To use the collagen device as an implant to replace, reinforce or strengthen bodily tissue, or to act as an adhesion barrier, the collagen device is placed in contact with bodily tissue and that contact is maintained until the collagen device is substantially resorbed within the bodily tissue.

    摘要翻译： 通过将胶原与纯水混合足以形成混合物的时间来制备胶原蛋白装置。 将混合物的pH调节至足以使胶原基本溶解的pH值。 将第一预定量的混合物放入容器中。 将混合物进行冻干处理并形成胶原装置。 胶原蛋白装置也是交联的。 胶原装置具有多个孔，其中大部分孔具有小于10um的直径。 为了使用胶原装置作为植入物来代替，加强或加强身体组织或作为粘附屏障，胶原装置被放置成与身体组织接触，并保持接触，直到胶原蛋白装置在身体内基本吸收 组织。

    Collagen device and method of preparing the same
    2.
    发明申请
    Collagen device and method of preparing the same 审中-公开
    胶原装置及其制备方法

    公开(公告)号：US20050283256A1

    公开(公告)日：2005-12-22

    申请号：US11171638

    申请日：2005-06-30

    申请人： Robert Sommerich ,  Laurel Macomber

    发明人： Robert Sommerich ,  Laurel Macomber

    IPC分类号： A61L27/24 ,  A61L27/56 ,  A61L31/04 ,  A61L31/14 ,  A61F2/02

    CPC分类号： A61L27/56 ,  A61L27/24 ,  A61L27/48 ,  A61L2430/32 ,  C08L89/06

    摘要： A laminated, bioimplantable dural graft product is configured for use as both an onlay graft and a suturable graft. The dural graft product is sufficiently pliable so as to sufficiently conform to a curvature of a tissue surface to which it is applied, such as the curved surface of a meningeal membrane. The use of the graft product can have improved properties, including suture retention strength and fluid impermeability. To use the dural graft product as an implant to replace, reinforce or strengthen bodily tissue, or to act as an adhesion barrier, the dural graft is placed in contact with bodily tissue and conforms to the curvature of the bodily tissue. Sutures can be used to maintain the contact between the dural graft and the bodily tissue.

    摘要翻译： 层压的生物可植入硬脑膜移植物产品被配置为用作衬垫移植物和可固定的移植物。 硬膜移植产品足够柔韧，以便与其所施加的组织表面的曲率（例如脑膜的弯曲表面）充分匹配。 接枝产品的使用可以具有改进的性能，包括缝线保持强度和流体不渗透性。 为了使用硬脑膜移植物产品作为植入物来代替，加强或加强身体组织，或作为粘附屏障，硬脑膜移植物与身体组织接触并符合身体组织的曲率。 缝合线可用于维持硬膜移植物和身体组织之间的接触。

    Access and delivery needle for percutaneous vertebroplasty
    4.
    发明申请
    Access and delivery needle for percutaneous vertebroplasty 审中-公开
    经皮椎体成形术的进出针

    公开(公告)号：US20070260258A1

    公开(公告)日：2007-11-08

    申请号：US11429017

    申请日：2006-05-05

    申请人： Robert Sommerich

    发明人： Robert Sommerich

    IPC分类号： A61F2/00

    CPC分类号： A61B17/8833 ,  A61B17/8819

    摘要： The vertebroplasty needle has two cannulae sharing a common distal end, wherein the cement injection cannula merges into a straight stylet cannula.

    摘要翻译： 椎体成形术针具有两个共同的共同远端的插管，其中水泥注射套管合并成直管形插管。

    Dural graft and method of preparing the same
    9.
    发明申请
    Dural graft and method of preparing the same 有权
    硬膜移植物及其制备方法

    公开(公告)号：US20070073415A1

    公开(公告)日：2007-03-29

    申请号：US11238717

    申请日：2005-09-29

    申请人： Robert Sommerich

    发明人： Robert Sommerich

    IPC分类号： A61F2/02

    CPC分类号： A61L27/24 ,  A61L27/50 ,  A61L2430/32

    摘要： A dural graft is provided having improved stiffness characteristics relative to conventional dural substitutes. The dural graft can be formed from a collagen material having a stiffness between about 0.1 pounds per inch (lb./in.) and 0.25 lb./in. Relative to the collagen material forming conventional dural graft substitutes, the decreased stiffness of the collagen material of the present dural graft can provide the graft with a relatively improved or increased pliability. As a result of the increased pliability, the dural graft can sufficiently conform to a curvature of a tissue surface to which it is applied, such as the curved surface of a meningeal membrane. The reduced stiffness of the collagen material can also provide for a relatively improved or increased flexibility or elasticity of the dural graft. The increased flexibility of the dural graft minimizes tearing of the graft when handled or manipulated during an implantation procedure.

    摘要翻译： 提供了相对于常规硬脑膜替代物具有改善的硬度特性的硬脑膜移植物。 硬脑膜移植物可以由具有约0.1磅/英寸（lb./in。）和0.25磅/英寸之间的刚度的胶原材料形成。 相对于形成常规硬脑膜移植物替代物的胶原材料，本发明硬膜移植物的胶原材料的刚度降低可为移植物提供相对改善或增加的柔韧性。 由于增加的柔韧性，硬膜移植物可以充分地符合其所施加的组织表面的曲率，例如脑膜的弯曲表面。 胶原材料的刚度降低还可以提供硬脑膜移植物的相对改善或增加的柔韧性或弹性。 硬脑膜移植物的增加的灵活性使得在植入手术过程中处理或操纵时移植物的撕裂最小化。