公开(公告)号：US20200225184A1

公开(公告)日：2020-07-16

申请号：US16829788

申请日：2020-03-25

Applicant: Roche Diagnostics Operations, Inc.

Inventor： Michael Lambertson ,  Klaus Bauer-Espindola ,  Samuel Evgin ,  Carina Horn ,  Michael Marquant

IPC: G01N27/327

Abstract: A method for determining an information on an equivalent series resistance is disclosed and comprises: generating at least one excitation voltage signal and applying the excitation voltage to at least two measurement electrodes; measuring a response signal; determining a signal flank from the response signal and determining an ohmic signal portion from one or both of shape and height of the signal flank; and determining the information on the equivalent series resistance from the ohmic signal portion.

公开(公告)号：US11680924B2

公开(公告)日：2023-06-20

申请号：US16829788

申请日：2020-03-25

Applicant: Roche Diagnostics Operations, Inc.

Inventor： Michael Lambertson ,  Klaus Bauer-Espindola ,  Samuel Evgin ,  Carina Horn ,  Michael Marquant

IPC: G01N27/327

CPC classification number: G01N27/3273

Abstract: A method for determining an information on an equivalent series resistance is disclosed and comprises: generating at least one excitation voltage signal and applying the excitation voltage to at least two measurement electrodes; measuring a response signal; determining a signal flank from the response signal and determining an ohmic signal portion from one or both of shape and height of the signal flank; and determining the information on the equivalent series resistance from the ohmic signal portion.

公开(公告)号：US20230393181A1

公开(公告)日：2023-12-07

申请号：US18448566

申请日：2023-08-11

Applicant: Roche Diagnostics Operations, Inc.

Inventor： Michael Lambertson

IPC: G01R27/14 ,  G01R31/36

CPC classification number: G01R27/14 ,  G01R31/3648

Abstract: A method for determining system resistance of at least one power supply of a handheld medical device, the method including: a) generating at least one excitation voltage signal, wherein the excitation voltage signal comprises at least one direct current (DC) voltage signal, wherein the excitation voltage signal has a fast transition DC flank of 20 ns or less; b) applying the excitation voltage signal to at least one reference resistor having a predetermined or pre-defined resistance value, wherein the reference resistor is arranged in series with the power supply; c) measuring a response signal of the power supply; d) determining a signal flank from the response signal and determining an ohmic signal portion from one or both of shape and height of the signal flank; and e) determining the system resistance of the power supply from the ohmic signal portion.

公开(公告)号：US20240426765A1

公开(公告)日：2024-12-26

申请号：US18755464

申请日：2024-06-26

Applicant: Roche Diagnostics Operations, Inc.

Inventor： Juergen Hildenbrand ,  Alexander Kramlich ,  Michael Lambertson

IPC: G01N21/94

Abstract: An in-vitro diagnostic (IVD) analyzer 200 comprising an optical detection unit 217 comprising a cuvette 214 for the optical measurement of a biological sample 2, 2′ is herein disclosed. The IVD analyzer 200 further comprises a piezo actuator 218 arranged on one side of the cuvette 214 configured to transmit ultrasonic waves 254, 254′ through the cuvette 214, a piezo receiver 218′ arranged on the opposite side of the cuvette 214 configured to receive ultrasonic waves 255, 255′, 255″ transmitted through the cuvette 214 and a controller 250 configured to operate according to either a lysis operating mode (L) or an air-detection operating mode (AD). According to the lysis operating mode (L) the piezo actuator 218 is configured to transmit ultrasonic waves 254′ through the cuvette 214 for disrupting cellular particles contained in the biological sample 2. According to the air-detection operating mode (AD) the piezo actuator 218 is configured to transmit ultrasonic waves 254 through the cuvette 214 and the controller 250 is configured to correlate changes in amplitude and/or shifts of phase of the ultrasonic waves 255, 255′, 255″ received by the piezo receiver 218′ relative to reference values with an eventual presence and quantity of air 3 in the cuvette 214, in order to determine if the optical measurement of the biological sample 2, 2′ is affected by the presence of air 3. A respective automated method of operating the in-vitro diagnostic analyzer 200 in order to determine if the optical measurement of the biological sample 2, 2′ is affected by the presence of air is herein also disclosed.

公开(公告)号：US11747377B2

公开(公告)日：2023-09-05

申请号：US17075303

申请日：2020-10-20

Applicant: Roche Diagnostics Operations, Inc.

Inventor： Michael Lambertson

IPC: G01R27/14 ,  G01R31/36

CPC classification number: G01R27/14 ,  G01R31/3648

Abstract: A method for determining system resistance of at least one power supply of a handheld medical device, the method including: a) generating at least one excitation voltage signal, wherein the excitation voltage signal comprises at least one direct current (DC) voltage signal, wherein the excitation voltage signal has a fast transition DC flank of 20 ns or less; b) applying the excitation voltage signal to at least one reference resistor having a predetermined or pre-defined resistance value, wherein the reference resistor is arranged in series with the power supply; c) measuring a response signal of the power supply; d) determining a signal flank from the response signal and determining an ohmic signal portion from one or both of shape and height of the signal flank; and e) determining the system resistance of the power supply from the ohmic signal portion.

公开(公告)号：US20210055336A1

公开(公告)日：2021-02-25

申请号：US17075303

申请日：2020-10-20

Applicant: Roche Diagnostics Operations, Inc.

Inventor： Michael Lambertson

IPC: G01R27/14 ,  G01R31/36

Abstract: A method for determining system resistance of at least one power supply of a handheld medical device, the method including: a) generating at least one excitation voltage signal, wherein the excitation voltage signal comprises at least one direct current (DC) voltage signal, wherein the excitation voltage signal has a fast transition DC flank of 20 ns or less; b) applying the excitation voltage signal to at least one reference resistor having a predetermined or pre-defined resistance value, wherein the reference resistor is arranged in series with the power supply; c) measuring a response signal of the power supply; d) determining a signal flank from the response signal and determining an ohmic signal portion from one or both of shape and height of the signal flank; and e) determining the system resistance of the power supply from the ohmic signal portion.