公开(公告)号：US20160075766A1

公开(公告)日：2016-03-17

申请号：US14946957

申请日：2015-11-20

Applicant: Roche Diagnostics Operations, Inc.

Inventor： Mirko Ritter ,  Styliani Tournavitti

IPC: C07K16/00

CPC classification number: C07K16/00 ,  C07K2317/20

Abstract: Herein is reported a cultivation system for cultivating a pool of ovine B-cells or single deposited ovine B-cells in the presence of phorbol myristate acetate (PMA).

Abstract translation: 本文报道了在佛波酯肉豆蔻酸乙酸酯（PMA）的存在下培养绵羊B细胞池或单一沉积的B细胞池的培养系统。

公开(公告)号：US11560420B2

公开(公告)日：2023-01-24

申请号：US16017043

申请日：2018-06-25

Applicant: Roche Diagnostics Operations, Inc.

Inventor： Mirko Ritter ,  Styliani Tournaviti

IPC: C07K16/00 ,  C12N5/00

Abstract: Herein is reported a cultivation system for cultivating a pool of ovine B-cells or single deposited ovine B-cells in the presence of phorbol myristate acetate (PMA).

公开(公告)号：US20180305441A1

公开(公告)日：2018-10-25

申请号：US16017043

申请日：2018-06-25

Applicant: Roche Diagnostics Operations, Inc.

Inventor： Mirko Ritter ,  Styliani Tournaviti

IPC: C07K16/00

CPC classification number: C07K16/00 ,  C07K2317/20

Abstract: Herein is reported a cultivation system for cultivating a pool of ovine B-cells or single deposited ovine B-cells in the presence of phorbol myristate acetate (PMA).

公开(公告)号：US20180164314A1

公开(公告)日：2018-06-14

申请号：US15892829

申请日：2018-02-09

Applicant: Roche Diagnostics Operations, Inc.

Inventor： Elke Faatz ,  Peter Muench ,  Mirko Ritter ,  Gloria Tabares

IPC: G01N33/569 ,  G01N33/543

CPC classification number: G01N33/56983 ,  G01N33/54393 ,  G01N2333/015

Abstract: Disclosed is a method for detecting a capsid polypeptide of a non-enveloped virus in a sample from a subject which includes (a) contacting the sample with a base, and (b) detecting a capsid polypeptide of the virus in the sample. Moreover, the present disclosure relates to a method for pre-processing a sample from a subject for detection of a virus, including contacting the sample with a base. Moreover, the present disclosure relates to kits, uses and devices related to these methods.

公开(公告)号：US20220018851A1

公开(公告)日：2022-01-20

申请号：US17265154

申请日：2019-08-08

Applicant: Hoffmann-La Roche Inc. ,  Roche Diagnostics Operations, Inc. ,  Ventana Medical Systems, Inc. ,  Prothena Biosciences Limited

Inventor： Christian Czech ,  Sebastian Dziadek ,  Lidija Pestic-Dragovich ,  Lei Tang ,  Thomas Kremer ,  Wagner Marcelo Zago ,  Tsu-Shuen Tsao ,  Adriana Racolta ,  Marta Canamero ,  Ronald Torres ,  Mirko Ritter

IPC: G01N33/68

Abstract: Methods and compositions for accurate identification of Parkinson's disease are disclosed. More particularly, the disclosure is directed to the determination of Parkinson's disease in ante-mortem tissue samples.